We are searching for computational PhDs and Postdocs to join our group in collaboration with @TreutleinLab . We have exciting single-cell technology projects that incorporate bioengineering, computation, biology, translation. Send CV to [email protected]
Thank you everyone for the congratulations and the large number of applications! I want to specifically encourage applications for these positions:
* Postdoc in structural biology (cryoEM, ideally with X-ray too)
* Full time lab manager/technician with wetlab experience
Diet/microbes place the gut epithelium as a nexus for evolutionary change. With @TheSpenceLab@genomeCraig, we use #organoids to explore how evolution prepared the developing human intestine for exposure to the environment. @ScienceMagazine#evodevo 🧵1/11 https://t.co/VKQtZ3LMaW
Thrilled to see #SAVANA out in @naturemethods🥳 SAVANA detects haplotype-resolved somatic SVs and copy number aberrations (SCNAs) and infers tumour purity & ploidy in clinical samples using long-read sequencing with or WITHOUT a matched germline control 👇https://t.co/AdZhqHUsDb
Modular integration of epithelial, microbial, and immune components to study human intestinal biology. Amazing team project with @_RubenL_, Marius Harter, @CY_Qianhui_YU, @mike_nikolaev, @TheLutolfLab, Nikolche Gjorevski, and many others @IHB_Research https://t.co/TUGJDzn93f
We are searching for 2 talented MSc students to join the group! If you are interested in using advanced organoid models to study regulators of intestinal differentiation or nutrient uptake, please apply! https://t.co/Wiz3VmYiDg and https://t.co/YQ3yG8KBek
@IHB_Research
A new peptide, BRINP2-related peptide (BRP) administered pharmacologically, reduces food intake and exhibits anti-obesity effects in mice and pigs without inducing nausea or aversion.
https://t.co/ZCT27ETW37
Great pleasure to host @SItzkovitz at @IHB_Research. Exciting talk & discussions on spatial transcriptomics of adult tissues. Including promising translational applications of using shed intestinal cells for longitudinal profiling of homeostatic and diseased cell states!
A big thanks to @SItzkovitz of @WeizmannScience visiting #TeamIHB! We were fascinated to learn how spatial and shed cell transcriptomics of the human digestive tract can illuminate how single cells in mammalian tissues collectively achieve physiological goals.
We are searching for a Master's Student/Intern to join the group for 6-12 months to work on large-scale bioimage analysis of complex human model system data!
Please send your CV to: [email protected]#IHB
Our first 2025 paper!
We discuss in @NatRevMCB how epithelial stem cells mechanically sculpt tissues, and how these forces are altered in cancer.
Great work from our former and current tumor mechanobiology experts Vince Fiore & @almagro_jorge
https://t.co/AJRBW8NVYK
iFlpMosaics are now published @naturemethods. A compendium of novel genetic tools and related methods for inducing and analysing genetic mosaics in a high-throughput manner. https://t.co/CjJWrW1o46 Tweetorial 👇
We updated our BindCraft preprint with lots of new exciting results! We release all our binder sequences and models, include more in silico analysis, novel design targets, and present AAV retargeting to specific cell types using de novo binders!
https://t.co/gg3KnI9keR
📢We are hiring a postdoctoral researcher 📢
Are your curious about the mechanisms driving metastatic spread? Do you have *bioinformatics* skills to help us unravel these mechanisms?
We (@Bergerslab, @ColindaScheele) may have your dream job @VIB_CCB!
https://t.co/BSqKGvFQ5x
Only 2 weeks left to apply for our junior & senior group leader calls! Join us in Basel to do cutting edge basic and translational research on human disease. In a very collaborative environment, where you can leverage state-of-the-art human model systems and technology platforms.
The GLP-1 drugs we've got now are just the beginning. The gut nutrient cell sensors ( a cellular instead of a peptide hormone target) have considerable potential.
Brief thread by @HansClevers on their new @ScienceMagazine paper