Vincent Lab

@unc_lineberger | Immunogenomics approaches to understanding tumor bio.
PI: @BenjaminGVincen | Lab Members:

[Benjamin Vincent @BenjaminGVincen]

Excited to release our software for tumor antigen identification using genomics data, a three-year @pirl_unc effort from amazing lead developer @spvensko in collaboration with @KOimmuno, @BortoneDante, @ChristofCSmith1, @ShengjieChai, @iskander... (1/n)
https://t.co/UGpoYWcTDq

[Vincent Lab @bgvincentlab]

Happening now!!!

[alex rubinsteyn @iskander]

Journal club for @pirl_unc will be a @TwitterSpaces today at 1pm: https://t.co/hXygWkct04

Neoantigen vaccine-induced CD4 T cells confer protective immunity in a [mouse MM via CD8 antigen spread to TAAs]

Paper: https://t.co/T98YEzIRjt

@ACIR_org summary: https://t.co/TY4iZ78kgj

[Vincent Lab @bgvincentlab]

Join us tomorrow (Mar 24) @ noon for a new twist on journal club! @TwitterSpaces

[alex rubinsteyn @iskander]

Trying something new for the @pirl_unc journal club, we're going to use @TwitterSpaces to talk about this paper:

"Neoantigen vaccine-induced CD4 T cells confer protective immunity in a [murine model of MM by antigen spread to TAAs]"

Thursday @ 12pm EST:

https://t.co/hXygWkct04

[Benjamin Vincent @BenjaminGVincen]

@KOimmuno is as brilliant and driven as they come, also an outstanding mentor and great person in general - It's exciting to see her hard work recognized. She's going to do great things in translational #AML research. Congrats Kelly! #doubledocs @pirl_unc

[Vincent Lab @bgvincentlab]

Big win for @KOimmuno Congrats!!! 👏👏👏

[Kelly Olsen, PhD @KOmudphud]

Feeling extremely psyched right now- got my score on my F30 grant resubmission! I’m really proud of my work on this one and how it came out, and super thankful for my lab’s help! ☺️ @bgvincentlab

[alex rubinsteyn @iskander]

Research crowd-funding experiment continues!

tl;dr Personalized cancer vaccines don't currently work, I want to fix that by testing (1) better vaccine types (2) better mutation sources from long-read sequencing.
GoFundMe: https://t.co/Oqqz9v7quu
Details: https://t.co/4Bc0RoqvYp

[Vincent Lab @bgvincentlab]

Check out some of our latest work!

[CRI iAtlas @iatlas_cri]

Explore immune analysis of 1142 samples, across 12 datasets, from studies of response to Immune Checkpoint Inhibitors (ICI) at https://t.co/TcSyKNPFGZ. Big thanks to our collaborators @bgvincentlab of the @UNC_Lineberger for all the work in processing and harmonizing these data!

[Vincent Lab @bgvincentlab]

Come join us!

[Benjamin Vincent @BenjaminGVincen]

Really excited to open this position with @BrianC_Miller and @JJMilnerLab, as part of building a core team in single cell immunogenomics in the @UNC_Lineberger Immunotherapy Group.

[Vincent Lab @bgvincentlab]

Congrats, @KOimmuno 🎉🎉🎉

[BBSP @ UNC @UNCBBSP]

@KOimmuno helps her mentees to keep a growth mindset, and she's a 2021-22 Science Mentoring Award winner. Read more about all of this year's honorees here: https://t.co/b2l2W4PXaP.

[Vincent Lab @bgvincentlab]

Way to go, @BenjaminGVincen 👏👏👏

[BBSP @ UNC @UNCBBSP]

Today we're honoring @BenjaminGVincen as one of our 2021-22 Science Mentoring Award winners, particularly for the flexibility he has offered mentees during the COVID-19 pandemic. Read more about all of this year's honorees here: https://t.co/b2l2W4yU8P.

[Benjamin Vincent @BenjaminGVincen]

This is fantastic

[Benjamin Vincent @BenjaminGVincen]

...and to @ReplicateBio for being ready for trials when our work is done. 4/4

[Benjamin Vincent @BenjaminGVincen]

Also many thanks to @DrLisaCarey, Chuck Perou, and @SeroBMT1 for leading and building an outstanding collaborative breast cancer clinical trials, translational biology, and immunology program @UNC_Lineberger to make this work possible... 3/4

[Benjamin Vincent @BenjaminGVincen]

Pam Kohl for leading this effort, for patient advocates Katie Mackin, Rhonda Howell, Missy Van Lokeren, and especially @paspears who believed in antigen-directed immunotherapy for breast cancer from the beginning, as well as to all the donors who supported this effort. 2/4

[Benjamin Vincent @BenjaminGVincen]

Deeply grateful to @SusanGKomen for this award to support developing precision immunotherapy in metastatic breast cancer. @SusanGKomen is critical in filling the gap between initial discoveries in the lab and new therapies being ready to deliver to patients. Huge thanks to 1/4

[William Y. Kim @WilliamKimMD]

💪work by Andrew Truong @UNC_PHCO & Mi Zhou in @jclinicalinvest & collaboration with @BenjaminGVincen showing class1 HDAC inhibition mediates antigen unlocking of tumor NeoAg and long term immunologic memory. Clinical trial NCT03978624 #bladdercancer

https://t.co/4ZcpvHE9HQ

[Kelly Olsen, PhD @KOmudphud]

Our paper is finally out! Last year I took a quick detour from cancer to covid and we did some vaccine design work with implications for future viral and cancer vaccines!

[Vincent Lab @bgvincentlab]

Fantastic tweetorial outlining our latest collaboration!

[alex rubinsteyn @iskander]

It's been a preprint for a while but a much improved version of our paper is out in @GenomeMedicine

"Landscape and selection of vaccine epitopes in SARS-CoV-2"

https://t.co/on6BQDi7VI

With @ChristofCSmith1 @KOimmuno @BenjaminGVincen + many others

Tweetorial:

1/

[Vincent Lab @bgvincentlab]

We wish you the best of luck in Boston! You will definitely be missed.