🕰️🚆🦠 Excited to share our new preprint: “Optimal transport fate mapping resolves T cell differentiation dynamics across tissues”!
We use OT to infer realistic CD8 T cell differentiation and migration trajectories from scRNA-seq timecourses.
https://t.co/rGzKrQV5qO
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Huge thanks to my my mentors Natalie Stanley (@natstann, @comp_cy) & Justin Milner (@JJMilnerLab) and to my co-authors Genevieve Mullins, Will Green (@greenwilliamd), Huitong Shi, Haidong Yi, and Kay Chung (@HKayChung1) 🙏
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Amazing work by talented graduate student @Pratt__Brandon and team from the @JJMilnerLab@HKayChung1. Be sure to check it out how they devised a way to unlock the therapeutic potential of CD8 T cells!
Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment @ImmunityCP@JJMilnerLab
https://t.co/QNWtsnnG8D
Excited to share the first of many works out of @JJMilnerLab. Be sure to check it out!
Enhancer-driven gene regulatory networks reveal transcription factors governing T cell adaptation and differentiation in the tumor microenvironment: Immunity https://t.co/y65fGS4kl4
Thrilled we were part of #KSTCells25 @KeystoneSymposia in Vancouver 🇨🇦 and reunited with T cell friends & colleagues! Huge thanks to co-organizers @theLundLab, @Joshilabyale & @DelgoffeLab. We can’t wait for the next one!!
Delighted to share that our feature selection method for improving inference of cellular trajectories is out today in @NatureComms! Biggest thank you to @natstann@purvislab @WStallaert @JJMilnerLab + team 😊
Paper: https://t.co/krTAphq5Wv . 🧵below.
Congratulations @alecplot for winning a best poster award at data science day for work predicting CD8 T-cell fates with @JJMilnerLab :) Truthfully, this a picture from last week, but is the same poster. Great job Alec.
So pleased to announce that @JJMilnerLab has earned our 2023-24 @theNCI SPORE CEP Award for his project, "Molecular regulation of T cell activity in pancreatic ductal adenocarcinoma." Congratulations, Dr. Milner, we're excited to watch your progress this year! @UNC_Lineberger
Happy to share that our story is out! @SciImmunology
Our study demonstrates that sustained CD28 signaling, is required to maintain PD-1+ CD8 T cells during chronic antigen stimulation (1/)
https://t.co/egNA7mJFYs
Here at UNC M&I, we're proud of our inspiring community of scientists who are changing the way we think about infections! We teamed with @kathaskfilms to provide an inside-look at how they do it. 📽️🔬
Full video: https://t.co/d3eOFOkMIa and at https://t.co/cGB3y0yann
@UNC_SOM