Bivona Lab

The Bivona Lab at @UCSF, @UCSFCancer and @czbiohub. Defining signal transduction properties that underlie tumor evolution and therapy response and resistance.

[Bivona Lab @BivonaLabUCSF]

Our latest paper is out now in @NatureGenetics! We investigate how APOBEC3B affects EGFR mutant non-small cell lung cancer evolution, from tumor initiation to targeted therapy resistance.

https://t.co/E5RS66qTEC

[Acquired Resistance to Therapy Network (ARTNet) @NCIARTNet]

Dr. Trever Bivona @BivonaLabUCSF presents on the progress of the BAATAAR-UP Center, which focuses on acquired resistance in lung cancer.
#ARTNetAnnual

[Collin Blakely MD, PhD @collin_blakely]

Pleased to report the results of our clinical trial: Neoadjuvant Osimertinib for the Treatment of Stage I-IIIA Epidermal Growth Factor Receptor–Mutated Non–Small Cell Lung #JCO #EGFR
https://t.co/gFT1kM0M9E
Thank you to all of the patients who participated.

[UCSF Helen Diller Family Comprehensive Cancer Ctr @UCSFCancer]

Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer | @BivonaLabUCSF @roose_jeroen @UCSF via @NatureComms https://t.co/aX3xSs38AI

[Acquired Resistance to Therapy Network (ARTNet) @NCIARTNet]

Just out in @NatureComms! Drs. Trever Bivona @BivonaLabUCSF, Jack Roth @JackARothMD and team uncover how the FAK-YAP signaling axis drives drug-tolerant cells and residual disease in lung cancer. #lungcancer #cancerresearch #ARTNetPublication
👇
https://t.co/oHyUl2Jp4p

[Acquired Resistance to Therapy Network (ARTNet) @NCIARTNet]

Just released on @NatureCancer:
"PERCEPTION predicts patient response and resistance to treatment using single-cell transcriptomics of their tumors in myeloma and breast cancer in both pre-clinical and clinical models."
Congrats to @BivonaLabUCSF!
https://t.co/YVkdwSrgV2

[Bivona Lab @BivonaLabUCSF]

Members of the Bivona lab at #AACR24 last week!

[Bivona Lab @BivonaLabUCSF]

@crispinhiley @drmcaswell @JulianDownward @CharlesSwanton Please also credit @DrPhilippeGui and #ManasiMayekar from our lab who are also first co-authors with @drmcaswell!

[The Francis Crick Institute @TheCrick]

In an international collaboration between @bivonaLabUCSF and @HarrisLabUTHSA in the USA and @Drmcaswell @SwantonLab and #DownwardLab at the Crick, researchers found that the mutagenic enzyme APOBEC3B can contribute to targeted cancer therapy resistance
https://t.co/0kPBfRjK9w

[Philippe Gui @DrPhilippeGui]

Very proud to have this work finally out in @NatureGenetics! This was a wonderful team effort; I would like to thank Manasi Mayekar and @BivonaLabUCSF. It was a privilege to work with our collaborators @drmcaswell and @CharlesSwanton from @TheCrick!

[Bivona Lab @BivonaLabUCSF]

Great work from @DrPhilippeGui and Manasi Mayekar, with @drmcaswell and @CharlesSwanton @TheCrick!

[Bivona Lab @BivonaLabUCSF]

Our latest paper is out now in @NatureGenetics! We investigate how APOBEC3B affects EGFR mutant non-small cell lung cancer evolution, from tumor initiation to targeted therapy resistance.

https://t.co/E5RS66qTEC

[UCSF Helen Diller Family Comprehensive Cancer Ctr @UCSFCancer]

This Friday, June 2 @UCSF Cancer Research Seminar | Silvio Gutkind, PhD @UCSDCancer @SilvioGutkind "Exploiting Cancer Signaling Circuitries in the Era of Precision Medicine: Novel Multimodal Targeted and Immunotherapies"
Hosted by @BivonaLabUCSF https://t.co/rAqcGhsN5t

[Tulpule Lab @TulpuleLab]

Finally this preprint! We describe functional ATM deficiency in Ewing sarcoma, a famously chemo-sensitive tumor, and link to native FET protein biology in DNA repair. Led by stellar postdoc @Shruti_menon09, in collab w/ @BivonaLabUCSF @SweetCorderoLab. https://t.co/yqliWmh3SH

[Turja Chakrabarti MD MS @DrTurja]

Excited to learn from all the innovation at #AACR2023 We describe T-cell clonal expansion and tumor neoantigens in lung cancer as a potential clinical frontier - learn more at our poster session! section 21: abstract #605 @BivonaLabUCSF @UCSFHospitals #immunology #CancerResearch

[Bivona Lab @BivonaLabUCSF]

Happy holidays from the Bivona lab! 🎄🎅

[Bivona Lab @BivonaLabUCSF]

Saying farewell and wishing the all the best to @TulpuleLab for the next step of his career at @MSKCancerCenter! Looking forward to more great science!

[Turja Chakrabarti MD MS @DrTurja]

Check out our abstract and poster EP08.02-217 Grateful for my mentor @collin_blakely , teammates @DanielLucasKerr and advocates @LAGurwitch @IASLC

[Bivona Lab @BivonaLabUCSF]

Fun day of hiking at the Bivona Lab! Good luck to @3doralb and @DanielLucasKerr for the next step in their promising careers 😀❤️

[Bivona Lab @BivonaLabUCSF]

Please read our latest work from @Shigeki04860554 out now in @jclinicalinvest: Inactivating genetic alteration of mRNA splicing factor RBM10 co-occuring with mutant EGFR limits EGFR inhibitor response in lung cancer https://t.co/QEBLC8QXrn

[Dian Yang @dianyang1117]

Excited to share our work using a CRISPR-based lineage tracer to track tumor evolution from a single transformed cell to an aggressive tumor in a genetically engineered KP-Tracer model. It is a great collaboration of the @JswLab, @LabJacks and @YosefLab.
https://t.co/at5yMZmtlF