Brinda Bala, PhD

🎓Postdoc at @OrdonezMoranLab @GutSC_lab @UoN_BDI @MedicineUoN Stem cells using organoids and bioinformatics 🧬👩🏻‍💻🔬

[Brinda Bala, PhD @brindabala]

Exciting News! My thesis work on targeting #FGFRs in #cholangiocarcinoma has been published. Our study highlights phospho-FGFR as biomarker for targeted therapies and also the potential of dual RTK inhibition.
#PhDComplete
@Cancers_MDPI https://t.co/L4n0dpr7Yv

[Brinda Bala, PhD @brindabala]

Very excited to share our recent findings on stem cell dynamics in chronic inflammation! We used a combination of bioinformatics, mathematical modelling, and organoids to explore how stem cells adapt and respond in inflammation.

https://t.co/ikkbGEmemL

[Organoid News @organoidscience]

There are only a few days left to submit your abstract for a chance to present your research to an international audience at Organoids Are Us 2025.

📆23 - 26 September 2025
📍Glasgow, Scotland

Find out more about the invited speakers and program here: https://t.co/rS1T1kMnFB

[Organoid News @organoidscience]

Using patient-derived #ColorectalCancer (CRC) organoids and functional assays, researchers investigated the role of stromal-secreted Wnt5a.

Wnt5a suppresses CRC progression via TGF-β/NOTUM/OLFM4 axis in patient-derived #organoids.

👉 https://t.co/regP6wwpIF

[Brinda Bala, PhD @brindabala]

Had the pleasure of attending the London Gastrointestinal Organoid Network (LION) at the Francis Crick Institute 🦁🧬 Grateful to be part of a vibrant community pushing the frontiers of organoid research! A fantastic day science and gut instincts! #LION #Organoids

[Hans Clevers @HansClevers]

Daisong Wang et al report that BEST4/CA7+ gut cells regulate electrolyte and water balance in response to diarrheal bacterial toxins These cells greatly increase in number when exposed to IFNγ https://t.co/wELRJqugHR

[POM lab @GutSC_Lab]

Congratulations to @samna_sagadevan, a talented PhD student from our lab, for presenting her research at the BDI Early Career Researcher (ECR) Theme Event!

@UoN_BDI
#ECR #CancerResearch #Organoids

[Ali Stunt 💜🇺🇦 @AliStunt]

Delighted to attend the Pancreatic Cancer Congress at the Karolinska Institutet here in Stockholm. Great talk by Dave Tuveson about the hallmarks of #pancreatic cancer . I’ll be speaking tomorrow about the patient experience & @P_C_E_

[Cell @CellCellPress]

In the latest issue! Empowering biomedical discovery with AI agents https://t.co/MEQsYJeRV6

[Simon Duerr @simonduerr]

This is great! @NIAIDNews have launched a collection of public domain illustrations (currently 550 individual icons) https://t.co/qYzIsbr0TH

[Waggoner Lab @LabWaggoner]

Intestinal tuft cells do not normally divide but become proliferative when activated by immunological cues to serve as reserve stem-cell population @Nature
@AmirGiladi @HansClevers
https://t.co/8dsiHX4pGf
https://t.co/G0PXnYHT2p

[Mike Schumacher @schumacherama]

Macrophages in ulcerative colitis

#IBD #microscopy

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

[Brinda Bala, PhD @brindabala]

Wrapping up the week with an insightful and inspiring lecture on stem cells and organoids by the pioneering @HansClevers.

#Organoids #GutSC

[Genetic Engineering & Biotechnology News @GENbio]

Human Stem Cells Repair Retinas in Monkey Models of Macular Holes

Experiments in Japanese macaques showed that transplanting human embryonic stem cell organoid sheets resulted in successful hole closure.
https://t.co/gUB06L45z1

[Hans Clevers @HansClevers]

Exciting study! Organoid models reveal a novel role for human tuft cells in gut regeneration upon damage. Video: Tuft cell division is triggered by IL-4, visualized in human gut AVIL-Clover reporter organoids (Credit: Daniel Krueger) https://t.co/gXhem2rw0B

[The Francis Crick Institute @TheCrick]

Researchers from the Crick and @UCLIoN have developed DNA molecules that use ‘invisibility cloak’ sequences to selectively target diseased cells in motor neurone disease.

The study was led by first author @OscarWilkins16 from the @FrattaLab

https://t.co/8Djv2aGCwC

[Waggoner Lab @LabWaggoner]

Human intestinal organoids containing viable tissue-resident memory T cells will facilitate the exploration of tissue–immune interactions and clinically relevant immune pathologies @NatImmunol N&V
https://t.co/55Mv3rK1hY
on @Nature
https://t.co/1EnhQ0LdEg

[POM lab @GutSC_Lab]

As part of National Postdoc Appreciation Week, we’d like to acknowledge and celebrate our incredible postdoc, @brindabala 🎉 Your hard work, dedication, and contributions to our lab and research are truly appreciated. Thank you for all that you do! 🙌
#NPAW

[Brinda Bala, PhD @brindabala]

@GutSC_Lab Thank you so much! 😊 I’m grateful for the opportunity to be part of such a wonderful team. Looking forward to more science together! 🙌 #NPAW2024 #Grateful

[Open Targets @OpenTargets]

🚨 Open Targets Platform 24.09 is out today!