Online today! Isolate mitochondria from your cell type of interest by using the MitoTag mouse model. Many thanks to all authors from the Perocchi & Misgeld labs for making this protocol possible. https://t.co/LRoE9CbplV
RESEARCH | R Nakai, T Yokota, J Brestoff et al. (Osaka Univ, JPN; @washu_pathology)
Administration of exogenous #mitochondria 💉or mitochondrial transfer from wild-type mice improves morbidity and mortality in a mouse model of #Leighsyndrome🐁
https://t.co/leWzOeET9U
The Vollum Institute is accepting applications for multiple faculty openings. We are interested in individuals whose research focuses on molecular and cellular neuroscience, genetics, neurodevelopment or signal transduction. #sciencejobs#neurotwitter
https://t.co/LnicYkonhZ
High mtDNA replication frequency is deleterious for newborn heart, causing dilated cardiomyopathy & ferroptosis. Our paper out in @NatureComms, outstanding work by @jclandoni. Thanks for crucial results @seminerkul@ASW_lab@HelsinkiUniMed@helsinkiuni
https://t.co/Ly8mLYDn1d
I'm excited to unveil the new lab art - "mitoclock" - created by talented @HSalmonowicz. This piece beautifully represents the inevitable passage of time and the dynamic nature of mitochondrial plasticity. Official postings coming soon - but we are hiring at all levels. R/T🙏
Excited to share our latest preprint, led by @MitoMonika Rachel Guerra & @mitocollier in collaboration with the Wittig lab & @Pagliarini_Lab
https://t.co/PnFtk6HlFT
If you are new to extracellular vesicle research and want some guidance on how to study them in metabolic regulation check out our comment in @NatMetabolism. Thank you Dan Lark @ERM_Lab, Kerstin Stemmer, and Wei Ying for these insights!
https://t.co/D3YG8So726
The application for summer 2025 Grass Fellowships is now live at https://t.co/tXUTvv8Y4N! Applications are due November 15. Please share with promising early-career neuroscientists. The Fellowship provides 14 weeks of sponsored research support at @MBLScience in Woods Hole, MA.
Researcher at @Coon_Labs @sinitcynlab @PatrickForny@Pagliarini_Lab@Morgridge_Inst apply new mass spectrometer technology to detect and quantify tens of thousands of protein phosphorylation sites within one hour or less of analysis
https://t.co/EQCegDgBi8
congratulations to Xhoela Bame on her amazing paper that defines the mitochondrial dynamics occurring during oligodendrocyte and myelin generation. https://t.co/HB0pyOEb6m
@MCBDartmouth@dartmouthartsci@NatureComms
Congratulations to Dr. Abigail Bartlett on receiving the WISL Award for Communicating PhD Research to the Public! Dr. Bartlett's thesis chapter is available to read here: https://t.co/EIWtdNKBzg
We wrote this to wrap our heads around the role of lipids in organelle communication. This field is growing so exponentially that several new major studies were published in the meanwhile during production.
Role of lipids in interorganelle communication https://t.co/KQgRaH3wcU
Neuronal activity-driven O-GlcNAcylation promotes mitochondrial plasticity https://t.co/auHxJUbS36
A sweet way to boost neuronal #metabolism and #mitochondria
Delighted to share new work led by Josh Meisel w/Gary Ruvkun using forward genetics to discover a new mode of post-transcriptional gene regulation. The mechanism involves mRNA methylation and P-bodies to allow neuron-specific mitochondrial gene expression.
https://t.co/umm7U7g9Wi
Protein structures reveal incredible mechanisms, but system-level questions were tough. How much can you generalize from one protein at a time? With AlphaFold that's changed. We predicted 11k enzymes and explore how evolution shaped them #AlphaFold https://t.co/QWifzcI7ct
Mitochondrial complex I construction relies on a patchwork of poorly defined "assembly factors." In work led by @andrew_sung, we used deep mutational scanning to elucidate NDUFAF6 function and predict variant pathogenicity.
@taylorlabncl@melogrammatical
https://t.co/0cFzaamamF