Carson Renaud

[Carson Renaud @carson_renaud]

@Jimbo_Wise Funny enough I was going to say thats when I read it also, everyone of those guys in it was either broke or on borrowed money before they made there big hit

[The Food Professor @FoodProfessor]

Dominic LeBlanc faced questions from the American media that he would never face in Canada—and it was painful to watch.

[Carson Renaud @carson_renaud]

@GaryMarcus Don’t worry all the important minerals and oil & gas come from provinces that don’t vote for Liberals/Carney and have zero intention of joining the easterners trade war.

[Mr Crumbsworth @MrCrumbsbody]

The beauty of No Deal is that it's unending. You can deliver No Deal every day for years, and campaign on delivering No Deal for years to come.

It's like fighting climate change, or reconciliation.

[Geiger Capital @Geiger_Capital]

Incase you’re confused…

Under Sheinbaum, Mexico has shifted toward greater alignment with the US and taken steps to restrict Chinese goods and investment into North America.

Under Carney, Canada has deliberately expanded their economic ties with China.

[Ben Bankas @BenBankas]

Carney didn’t want to do the trade deal because he knew it would help fix Canada. US was asking Canada stop draconian speech laws and outdated environmental laws hampering investment but Carney doesn’t want Canadians to realize how easy it is to unfuck everything..

[J.J. McCullough @JJ_McCullough]

All the Canadian pundits are braying in unison that “no deal is better than a bad deal!” I have no idea what this means, or what their definition of “bad” is. 50% tariffs are “better” than what, exactly? Getting rid of the Online News Act that gives them their precious subsidies?

[J.J. McCullough @JJ_McCullough]

Prime Minister Carney is admitting he pulled out of the trade talks with the US in order to protect subsidies for the Canadian media, Bill C-11’s provisions to force online streamers to push “Canadian content,” and bilingual packaging. He said this stuff was beyond compromise.

[Jamil Jivani @jamiljivani]

This is a solemn moment for hundreds of thousands families across Canada.

In homes on every corner of this nation, working people are having tough conversations about what their future looks like and how they will provide for their families.

Make no mistake. Since the beginning, in their public communications, Liberal politicians like Mark Carney and Doug Ford have put their political self-interests ahead of Canadian workers.

As leaders, I believe it's incumbent on us to be servants for the people who elected us, and the families who are relying on us to bring home the dignity that comes with a paycheque.

I'm not giving up. I will continue fighting for hardworking people in my community and across Canada.

I know what it means to have real questions about putting food on the table and for working people to endure hardships. Canadians should know that Conservatives are in your corner. And I want to thank Pierre Poilievre for encouraging me to continue fighting for this country's working people.

In your service,
Jamil

[Murtaza Hussain @MazMHussain]

Opinions of AI are much more positive in Asian countries where the technology is being described as a public utility made available open-source.

In the U.S. views are dismal as also seen in data center backlash and its no wonder as the main message is that AI will be used as a tool to eliminate jobs and consolidate power within a small circle of oligarch-run companies whose leaders seem to hate and fear the general public.

[Carson Renaud @carson_renaud]

@Graff2023 If we get rid of supply management that’s a win for Canada

[Carson Renaud @carson_renaud]

Agreed, China will be limiting there replenishment capacity of advance missiles via rare earths. US requires large quantities of rare earths for the standard missile based defence (think Germanium, etc).

US cannot restock, replenish or re-industrialize with the US dollar as strong as it is. US must pull back from the Eastern hemisphere rebuild their industrial base and try and focus on the Western hemisphere and utilizing there advantages in that region before thinking about re-engaging the emerging global superpowers in the east.

[QtSciG @QtSciG]

@stephen_taylor With KXL resurrected, Carney can argue increased export capacity for Alberta and renege on the pipeline to Tidewater keeping his Net Zero Climate Jihadists pacified.

Trump keeps Alberta oil below world price.

AB gets screwed but @ABDanielleSmith could claim she got something.

[Paul Vieira @paulvieira]

Canada is getting more information about trade talks from USTR Greer than from Canadian officials, like Dominic LeBlanc.

[Carson Renaud @carson_renaud]

@KamilPawlo72429 @Thorkill65 Russia easily could turn of gas flows to Europe. Europe is buying all Russian LNG cargoes out of Yamal. Europe is at 59% of gas in storage for winter for this time of the year well below targets. 40% of Europe’s gas/energy comes from Russia.

[Mongo Like Sheriff Bart @boyko_tim84075]

Raymonde Gagné
Unelected Senator of Canada
$260,000 per year
Approx $900,000 in travel expenses!
Japan $107k
South Africa $56k
Switzerland $52k
France $30k
Spain & UK $105k
Brazil $60k
New Zealand $118k
Switzerland (again) $25k
Africa $101k
UK/Ireland $82k
Belarus/Romania $108k

[tobi lutke @tobi]

dystopian

[Toronto Sun @TheTorontoSun]

Canadians spent more on taxes than basic necessities in 2025: Study https://t.co/4hKAyt2eTt

[Patrick Hsu @pdhsu]

Today in @ScienceMagazine, we report a new DNA editing technology to seamlessly write massive changes into the right place in the human genome.

The reason gene editing hasn't transformed human health is that current gene editing technologies like CRISPR are very limited.

The problem with CRISPR is that it cuts up your DNA, and then hopes that unreliable cellular DNA repair will make the wanted edit. @geochurch famously called it genome vandalism. More precise versions of CRISPR only edit less than 100 bases - often only a single base. Therefore, it's not suited to make large changes safely.

However, most diseases are not the result of mutations in one location. Instead, their causes are spread all across the 3 billion base pairs in the genome.

We found bridge RNAs in bacterial “jumping genes” that allow us to make safe and arbitrary changes (insert, cut out, or flip) to every nucleotide within (up to) a 1 million bp sequence in your DNA.

In the paper, we show that we can correct the disease-causing DNA repeats that cause Friedreich's ataxia (which is a rare neurological disease). The same approach could be applied to Huntington’s and other repeat expansion disorders.
At @arcinstitute, we're working towards a full Turing machine for biology. Evo, our DNA foundation model, helps us design the optimal healthy DNA sequences. And Bridge recombination gives us the ability to seamlessly write these changes into the right place in the genome.
This work was a wonderful collaboration with my @arcinstitute cofounder @SKonermann and led by the indefatigable @ntperry13, alongside our amazing bridge editing team: @BartieLiam @dhruvakatrekar @Gabogonzalez515 @mgdurrant @james_jw_pai @AlisonFanton Juliana Martins Masa Hiraizumi @chiaroscurale @hnisimasu