Researchers from the Mattiroli group discovered that DNA packaging in cells can directly impact the speed of DNA copying during cell division. The packaging sends signals through an unusual pathway, affecting the cell’s ability to divide and grow. More: https://t.co/Fgv1RynmHK
In situ sequencing measures the 3D location and genomic position of each DNA fragment, letting us trace the path of every chromosome in the nucleus
We also do expansion IF imaging to measure which fragments co-localize with protein landmarks
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Ready to establish your own research group at the Hubrecht Institute for molecular and developmental biology? We’re seeking a tenure-track group leader to develop an innovative research line within our vibrant scientific community. Learn more & apply!
https://t.co/hXb5jz43oG
🎉Big news!
Dr. Peter Zeller, soon joining us at the IES, has been awarded the prestigious #ERC Starting Grant for #scEpiTarget!
His groundbreaking work in #epigenetics could revolutionize treatments for major diseases.
Watch the📽️👇
Stay tuned for updates & hiring opportunities!
Calling all emerging scientists - it’s time to send us an application! 😉😎 Lead your own #MaxPlanck Research Group w/ €2.7M in funding over 6 yrs, full independence & resources to hire staff. State-of-the-art infrastructure awaits you!🌟 Apply today➡️https://t.co/cHxPLyRj9x
Congrats to my postdoc Cecilia Pessoa Rodrigues on her Science paper. We show that dsRNAs from endogenous viral elements bind to TLR3, inducing the don't eat me signal, B2m, on HSCs. This protects the stem cell from phagocytosis by macrophages. https://t.co/eNvPmXtTM5
Erasmus Virtual Hematology Lectures starts again on Monday September 2 at 16.00 CET!
We have MAXIM PIMKIN from Harvard/Boston with: "Gene-regulatory networks in leukemia maintenance and immune escape".
Link: https://t.co/ICOMFc5jv5
Spread the news!
@pimkin
New paper from our group! Fantastic work by @gioacchino_e@ckoyunlar Wei Zhang and many others
https://t.co/3d08Xdz5pf
a #zebrafish model showing a feed forward mechanism regulating ectopic expression of Gata2b in HSPCs driving #MDS in #GATA2deficiency, a 🧵
Very happy our scEdU-seq manuscript is published in @naturemethods! Big shoutout to @BVincentv, @AlexandervanOu1 @marcelvanvugt, @Acebron and @Anchel_91 for their contribution to the final product! For those interested here is the link to the paper https://t.co/T0doDjjiiM
We are excited to share our latest preprint on a new solution to next-generation peptide/protein sequencing.
Peptide sequencing via reverse translation of peptides into DNA https://t.co/IFtp2hGZ4I
“This is crazy molecular biology. I would have never guessed this type of mechanism existed”
Bacterial defensive systems scramble the standard workflow of life https://t.co/Rel9sdDYRo
June 10/11:
PhDs and postdocs will present their work at the "7th Molecular Hematopoiesis Workshop" in Rotterdam.
Special guests: Ari Melnick, Iannis Aifantis, Els Mansell, Irene Roberts, George Vassiliou, Jamie O'Sullivan, Charles Mullighan.
Join? Go to https://t.co/CFA0WHM2Hk
🚨🚨🚨🚨
Our new preprint is out!
“Pre-existing stem cell heterogeneity dictates clonal responses to acquisition of cancer driver mutations”
🩸🧫🧪🧬
https://t.co/CYOsKcssPy
The superteam of @cancer_curious and Dani Fernandez tackled a major unanswered question in HSC bio.
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"success" means different things to different scientists. It could mean winning prizes & curing diseases, it could also mean a TT job at an Ivy, running a big lab, or publishing a lot. But to some it means running a small lab, being a good teacher/mentor, working on a topic you❤️