Escalante-AlcaldeLab

Last night I lay in bed looking up at the stars in the sky and I thought to myself, where the heck is the ceiling?~Dilbert

[nature @Nature]

Long thought of as support cells, astrocytes are emerging as key players in health and disease

https://t.co/XCrwQPrfMG

[Columbia University's Zuckerman Institute @ZuckermanBrain]

Collaborations are moving neuroscience forward. Scientists from 20 institutions (including ours!) created the first brain-wide map of individual neurons’ activity in mice for the @IntlBrainLab. Video from @SWC_Neuro https://t.co/bKaaZp3myK

[Escalante-AlcaldeLab @DiI63]

😮

[Martin Smith @martinalexsmith]

How cool is this? Michal Lipinski from @broadinstitute presenting stacked #Illumina spatial slides of the mouse brain with subcellular transcriptome resolution #AGBTGM

[MIT Picower Institute @MIT_Picower]

A new technology developed at MIT enables scientists to label proteins across millions of individual cells in fully intact 3D tissues with unprecedented speed, uniformity, and versatility. https://t.co/oDsdgpYNmN #neuroscience @MITChemE @ScienceMIT @MIT_IMES @mitbrainandcog

[epithelial mechanics fan club @EpiMechFC]

Chuai, M., Serrano Nájera, G., Serra, M., Mahadevan, L., & Weijer, C. J. (2023). Reconstruction of distinct vertebrate gastrulation modes via modulation of key cell behaviors in the chick embryo. Science Advances, 9(1), eabn5429. https://t.co/dXKEr8DboJ #EpithelialMechanics

[Escalante-AlcaldeLab @DiI63]

🤩

[Trends Cell Biology @TrendsCellBio]

Single cell lipid biology https://t.co/QmgWqyiDvv

[Elisabeth Kugler @KuglerElisabeth]

Curious about Biomedical Image Analysis?

Join our Introductory Course and gain hands-on experience with essential techniques like:
🔹 3D Image Understanding
🔹 Image Filtering
🔹 Image Segmentation
🔹 Image Quantification in 3D+ with Fiji

Register: https://t.co/V0hhnm3oGI

[Marissa Gredler @mlgredler]

The Gredler Lab @Harvard @MCB_Harvard is hiring Postdoctoral Fellows! If you are interested in using high-resolution imaging of live embryos to ask how cells build tissues, please apply at the link below. #DevBio #sciencenews https://t.co/KlRwdAPN2y

[Ali Max Erturk @erturklab]

Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵👇@cellhostmicrobe https://t.co/IEGx7HIrXf

[Eric Topol @EricTopol]

The #SARSCoV2 spike protein can persist in the brain—skull bone marrow and meninges—to induce neurologic damage https://t.co/FtsftML1m4 just published @cellhostmicrobe @erturklab open-access

[HHMI | Janelia @HHMIJanelia]

In a new review, Group Leaders @computingnature & @marius10p examine methods for analyzing large-scale neuronal recordings, how these tools have enabled progress in answering longstanding questions in neuroscience, and what advances & challenges lie ahead. https://t.co/ExI0dfTzRy

[Escalante-AlcaldeLab @DiI63]

Exciting work of this long time no see colleague.

[Heiko Lickert @LickertHeiko]

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”.
https://t.co/GKx6eslJz0
A tremendous collaborative effort led by @JohannaSiehler, @BilekovaSara and other members of the @LickertHeiko lab.

[Escalante-AlcaldeLab @DiI63]

🤩

[Matthew Stower @MSTO89197800]

Feeling festive! Happy to share our new bioRxiv pre-print - investigating the role of calcium in the early embryo (with a festive themed post)
https://t.co/2D0t8iNqsY

[Escalante-AlcaldeLab @DiI63]

👏🏼👏🏼👏🏼

[Mackenzie Weygandt Mathis, PhD @TrackingActions]

✨🥰 check out our article - and cover 🤩- about Decoding the Brain in @CellCellPress

https://t.co/HWBquErj0f

We review the mathematics, current approaches, and muse about the future…

#BCI #neuraldecoding #neuroAI

Thanks to my awesome co-authors Adriana Perez Rotondo, Edward Chang, @AToliasLab & @TrackingPlumes

[eLife - the journal @eLife]

The components of a synapse revealed by expansion microscopy of a single synaptic contact. https://t.co/kJGdohHKHR

[Escalante-AlcaldeLab @DiI63]

The power of AlphaFold

[Victoria Deneke @deneke_v]

The life of each one of us began when a sperm and an egg came together. But what actually happens at a molecular level?
Our latest work @PauliGroup @CellPress reveals a conserved fertilization complex that bridges sperm and egg in vertebrates! (1/8)
https://t.co/FT5oxJb1dx

[nature @Nature]

Glucose has a surprise role in directing cell fate and migration https://t.co/dYhI6HAgb3

[Escalante-AlcaldeLab @DiI63]

Of metabolism and gastrulation. Very exciting work.

[Berna Sozen @BernaSozen_]

Our latest out today @Nature!
We revisit a century-old theory and show that metabolic gradients work hand-in-hand with genetic&signalling instructions to shape the embryo. Glucose isn't just an energy source, it acts as a major conductor of the body plan🍬
https://t.co/mfx6Hk7nma

[Perez-Martinez Lab @mitocondrias204]

🧪¿Te has preguntado para qué sirve respirar y oxigenarnos? ¿Porqué morimos si no respiramos?

Resulta que respirar sirve para obtener la energía que necesitamos. Sigue el hilo 🧵👇🏻. #HilandoCiencia2024

[Eric Betzig @Eric_Betzig]

10/ With adaptive optical lattice light sheet microscopy (AO-LLSM), we’ve opened a stunningly beautiful and humblingly complex world of 4D subcellular processes viewed with high definition in living transparent multicellular organisms such as zebrafish.
https://t.co/bB5q4sXuQI