Exciting to see these results out! Lots to build on - congratulations @ superb MSK pancreas team (no biases!) and complex insightful analyses led by @CentralParkWMD@MSKCancerCenter and as #ASCO23 winds down…. back to the real work of implementing all the learnings to practice!
Pembro + olaparib maintenece #POLAR trial (B&C) in non-BRCA potential #HRD stage IV #PancreaticCancer n=30. Well-tolerated. 30% had no progression for > 6mo WITHOUT chemo. Deep science & POLAR A #BRCA awaited. #gratitude & 💜to MSK team & patients #ASCO23 https://t.co/kxLxxCLa4n
Honored and proud to be part of this amazing team❤️ It is never too late, or too early, to target RAS: this perspective provide an overview of the current and future features of pancreatic cancer interception @HopkinsMedicine@hopkinskimmel@KRASKickers@CD_AACR
Thanks to @medpagetoday for highlighting our @JCO_ASCO article. Need to write more soon on how primary palliative care looks/works in a busy oncology clinic. Shout out to my amazing clinic team (including Irena quoted) who are the reason we can provide this comprehensive care.
Welcome to @Perlmutter_CC@rutikamehtaMD!
So excited to have you as our new director of upper GI medical oncology, delivering exceptional cancer care, clinical trials & translational research for patients with gastric and esophageal cancers.
@JohnPLeonardMD@DrMhidalgo
This will be absolutely a fun 🤩 event.
Looking forward to interactive and insightful discussions 🎙️with the KOLs 👑 who shape this field in K/RAS 🧬 field!
Happy 😆 to join Toni @GIcancerDoc Eileen @EileenMOReilly and John Strickler 👏
KRAS-mutant GI malignancies are one of the fastest-moving areas in oncology right now.
Let’s dig into the biology, the evolving treatment landscape, and real-world case discussions with colleagues at our 2026 ISGIO Spotlight CE Session: Precision Pathways in RAS-Mutant GI Malignancies.
Bring your toughest questions (don’t be kind. @GIcancerDoc will take it 🤣) and we will talk through it together. I hope to see you there October 2-3! Register with code PARK for free registration: https://t.co/V3c1IjJ7xl
#GRIT #PancreaticCancer #GIcancers #RAS #KRAS #biliarycancer #coloncancer #appendicealcancer
Very grateful for this @JamesClearyMD means a lot coming from you. 🙏
We think the most interesting question now is how to turn this biology into the next generation of strategies for HRD pancreatic cancer. There is so much still to understand across DNA repair, neoantigens and immune engagement. 🧬
Would love to compare notes and think together about where this can go next.
You have super exciting work so would love to connect. Maybe at DFCI BRCA symposium around 11/11 if you are around? 😉
Pancreas cancer patients, families, loved ones, carers &the general public all welcome to a very special event Weds Sept 23 @HerbertParkHotel Ballsbridge 630pm Drs Eileen O’Reilly from New York & Grainne O’Kane from Vincent’s will discuss new treatments.
RAS therapies are reshaping pancreatic and colorectal cancer treatment. Get your pressing questions on testing, sequencing, and managing toxicities answered by topexperts at ISGIO 2026 on October 2. Free reg use code: PARK @CentralParkWMD@oncodaily@GIcancerDoc@EileenMOReilly
And if you're interesting in joining us in our adventure into toxicity, germline genetics, and precision safety, consider applying to this open postdoctoral position.
I’m incredibly grateful for your mentorship, trust, and support throughout this project. It has been such a privilege to build this story together with you and the whole team. 🙏🌟
Years of work distilled into one lesson. Finding expanded T cells was not enough. We had to trace the same clonotypes from blood into tumor, localize them spatially and ask what they recognized. Deeply grateful for the mentorship, trust and extraordinary team that made this possible!