Yane-Shih Eric Wang

Protein Chemistry, Protein PTMs, and Biocatalysis

[Nature Reviews Drug Discovery @NatRevDrugDisc]

For readers interested in bispecific antibodies in oncology, here's a review #ASCO26
https://t.co/ybCSH28xRg
https://t.co/BD7jrqQWa4

[Yane-Shih Eric Wang @ericyswang]

@InfosysPrize @KamatLab_IISER @IISERPune Congratulations!

[Yane-Shih Eric Wang @ericyswang]

Our new JACS paper online! So exciting! A human ferritin-based #metalloenzyme catalyzing site-specific #histidinePTMs in proteins designed by @ericyswang @IBCSinica @AcadSinica sets the stage for novel in vivo #EnzymeTherapies. | @J_A_C_S

[J. Am. Chem. Soc. @J_A_C_S]

Site-Specific Histidine Aza-Michael Addition in Proteins Enabled by a Ferritin-Based Metalloenzyme | Journal of the American Chemical Society #SiteSpecific #Histidine #AzaMichael #Proteins #Ferritin #Metalloenzyme https://t.co/W5b7K0FB1M

[The Nobel Prize @NobelPrize]

Remembering biochemist Har Gobind Khorana who helped us to crack the genetic code.

Khorana shared the 1968 #NobelPrize in Physiology or Medicine with Robert Holley and Marshall Nirenberg "for their interpretation of the genetic code and its function in protein synthesis."

[Todd L. Lowary @Lowarylab]

Come join us in at @AcadSinica and @IBCSinica for PhD studies in English. Great science, great infrastructure, great city.

[Asaf Levy אסף לוי اسف ليڤي @AsafLevyHUJI]

A new Legionella protein toxin that mimics tRNA and blocks translation

https://t.co/b3AQYBj61U

[Luis Escobar @luisescobar1992]

I am delighted to share our work “A prebiotically plausible scenario of an RNA-peptide world” published in @Nature today. @CarellGroupLMU @AvHStiftung https://t.co/CTFxXjLfmL

[Kazuaki Amikura @amikura1986]

Congratulations, Xian Fu (Felix)!
tRNA discriminator base defines the mutual orthogonality of two distinct pyrrolysyl-tRNA synthetase/tRNAPyl pairs in the same organism https://t.co/JmhGcRKwz0

[nature @Nature]

Nature research paper: Reversible RNA phosphorylation stabilizes tRNA for cellular thermotolerance https://t.co/GzxcS5VyiZ

[Code script @nonstandardcode]

Nanobody assemblies with fully flexible topology enabled by genetically encoded tetrazine amino acids https://t.co/OVIkzsLrtE

[Frontiers - Chemistry @FrontChemistry]

New Research: Ferritin Conjugates With Multiple Clickable Amino Acids Encoded by C-Terminal Engineered Pyrrolysyl-tRNA Synthetase: This study reports the application of expanding genetic codes in developing protein cage-based delivery systems.… https://t.co/bQp537OWuU #chemistry

[Yane-Shih Eric Wang @ericyswang]

Thrilled to shared our new publication: Ferritin Conjugates With Multiple Clickable Amino Acids Encoded by C-Terminal Engineered Pyrrolysyl-tRNA Synthetase https://t.co/yTt4eHQmz2

[drug hunter @drughunter_com]

FDA Approved ADCs and Warheads - 2021 | https://t.co/7LgcpEjCMG

A whopping 8 ADCs were approved in the last 4 years and ADCs are back on the front pages of the news.

Here's a visual “rest-stop” to catch up on what’s currently approved.

#biotwitter #chemtwitter

[Yane-Shih Eric Wang @ericyswang]

Open for submission: #Biocatalysis: Exploring and Designing Biocatalysts for Molecular Synthesis, and DNA/Protein Bio-Macromolecule Modifications https://t.co/k8Y0fSb32D #mdpicatalysts via @Catalysts_MDPI #syntheticbiology #proteinPTM #DNAPTM #chemistry #enzyme #proteindesign

[Ethan Goddard-Borger @ethangbaus]

Our latest work on tryptophan C-mannosylation is out today in @J_A_C_S. It describes photoreductive cross-coupling methods for the late-stage C-mannosylation of peptides. Congratulations to Runyu @mryzjjs and the rest of the team. 1/4
https://t.co/KhDLfkiHuG

[Yane-Shih Eric Wang @ericyswang]

All the best to lab graduate student Han-Kai Jiang. He will start his oversea exchange study at Yale on August this year. His research is supportdled by MOST Taiwan and TIGP-CBMB program, Academia Sinica. #research #oversea #PhDlife #IBC #AS #NTHU #TIGP

[Enzyme Chemistry @EnzymeChemistry]

Unlocking Iminium Catalysis in Artificial Enzymes to Create a Friedel–Crafts Alkylase by @reubenlg, @Zhi_Jason_Zhou, @IvanaDrienovska, and Gerard Roelfes @RoelfesGroup @univgroningen in @ACSCatalysis https://t.co/sxvlFMo4Gf

[Yane-Shih Eric Wang @ericyswang]

Having a mug gift from ACS @AmerChemSociety today. It makes my day. Wondering who have 50th element mug or more....
#realchemlife #ACSmug #ACS

[Yane-Shih Eric Wang @ericyswang]

Exciting to see our #CoverArt published with #first issue of new volume of @BiochemistryACS. Also check out the associated #Ub-#SUMO2 dimer synthesis and using for probing #USP7 #DUB selectivity. https://t.co/kaHkBn1lDr

[Biochemistry @BiochemistryACS]

Issue 1 of volume 60 is live! Authors include Gerald Joyce, Paul Park, Jan Raap, Sergei Dzuba, @SobradoLab, Michael P. Stone, Julian Eaton-Rye, Alexey Aleksandrov, Zhengren Xu, Chin-Yuan Chang, and William Atkins. https://t.co/lwtVFPciYQ

[Yane-Shih Eric Wang @ericyswang]

I choose our second @BiochemistryACS paper published in 2020 that describing #Ub-#SUMO2 unbiased synthesis and their interactions with #USP7. We are so thrilled to see our #CoverArt was selected to published here. So exciting! #Biochemistry https://t.co/qG6PeEAi3B

[Biochemistry @BiochemistryACS]

Happy 2021, the 60th Anniversary year of @BiochemistryACS, to all of our authors and readers! What is your favorite Biochemistry manuscript from our 60 year history?