Assistant Professor @USC | Postdoc with Joe Gleeson | PhD with YeGuang Chen | Focus on neurological disorders and brain organoids | Opinions are my own
Congrats @SimonsFdn 2025 Fellows-to-Faculty Awardees, especially @HarryKiv from @jogleeson_ucsd lab (red). Harry was selected based on his proposal to map origins of neural crest derived neurons in #autism relevant conditions. https://t.co/Qwzgq2djsu
Dr. @ErinLWang and a team in Dr. @JoGleeson_UCSD's lab generated a brain #organoid atlas from patients with neurodevelopmental disorders. 🗺️
Read the @CellStemCell article: https://t.co/HFTFAD4hRq
Learn more in this week's episode: https://t.co/hMbd02QRbO
Grateful for a long journey of joyful collaborations with @emukamel, Junhao Li, Yuji Nakamura (UCSD) & students Yang Liu, Kevin Camey @USCNGP. Huge thanks to Joe @jogleeson_ucsd for his generous support & training!!
Thrilled to share our new paper in @CellStemCell! We present a brain organoid atlas for NDDs, integrating hBO phenotypes, transcriptomics, WES, and brain imaging. We hope this resource inspires new studies and therapies for NDDs!
Check out our new resource paper @CellStemCell, where we present a brain organoid atlas of human neurodevelopmental disorders. Surprising was that nearly all patients had abnormal organoids. The challenge was aligning defects to clinical. https://t.co/0YtGTd4Dwb
Skull derived immune cells in brain tumors of patients... Therapeutic implications could be major, once we figure out how to manipulate skull bone marrow and its associated immune cells || Cranioencephalic functional lymphoid units in glioblastoma https://t.co/26I9n92c6A
New publication in Cell Stem Cell! 🎉
"Vascular architecture regulates mesenchymal stromal cell heterogeneity via P53-PDGF signaling in the mouse incisor"
https://t.co/MFPYmn82RV
Our latest @Nature paper is out! We show that transplanting mitochondria into endothelial cells boosts their ability to form blood vessels in ischemic tissues, with mitophagy as the key mechanism. A potential game-changer for vascular cell therapies. https://t.co/ViscFIc9sv
In our new Resource Article @CellStemCell we describe an expandable nephron progenitor cell-based kidney organoid platform with broad applications. Unlimited supply of human nephron progenitor cells makes us one step closer to making a synthetic kidney for transplantation.
Did you know that Mary Beth Hatten (@khats97) was the first woman to be named head of a laboratory at Rockefeller? Watch her discuss her life and work in this interview from our #oralhistory project.
https://t.co/1hz0oETjFO
Exciting breakthrough: A new microfluid-based human pluripotent stem cell model now allows researchers to accurately model both the rostral-caudal and the dorsal-ventral features of early human central nervous system development. https://t.co/zhCblLgRf7