Ethan Solomon

Research-track resident in psychiatry @ Stanford, MD/PhD @ Penn, SB @ MIT. Interested in the neural electrophysiology of cognition, perception, and psychiatry.

[Corey Keller @DrCoreyKeller]

New TBS findings w/ iEEG by brilliant @YuhaoHuangMD! TBS → plasticity in minutes; DLPFC stim affects ACC; Connectivity predicts response! 🧠⚡️Opens new avenues for TBS optimization. More w/ TMS-iEEG, 3x TBS & units soon! Thanks @ACPaulk & team for collaborating 🙏 @StanfordBrain

[Danny Huang, MD @YuhaoHuangMD]

Theta-burst stim (TBS) is used to treat depression, but how does it work? I dug into this question in my research yr with @DrCoreyKeller @ACPaulk, now out in @NatureComms, finding that TBS can produce plasticity-like changes in just minutes of stim. https://t.co/hDCFvqwsxJ

[Ethan Solomon @esolomon]

8/ This work was a huge team effort! Big thanks to all contributors from @StanfordBrain and @UIowaNeuro including @NickTrapp13, @Hiroyuki_O,  @JeffreyBondWang, @DrCoreyKeller, and others!

[Ethan Solomon @esolomon]

7/ A deep dive into nature of provoked rhythms -- big shoutout to FOOOF (https://t.co/DMzwOLNL6u, @Tomdonoghue ) -- revealed that single-pulse TMS caused the emergence of "true" theta oscillations in ACC and orbitofrontal regions.

[Ethan Solomon @esolomon]

6/ Anterior cingulate cortex -- a key node in networks mediating psychiatric illness like depression -- was specifically engaged in the theta band by DLPFC stimulation.

[Ethan Solomon @esolomon]

5/ TMS to the posterior parietal cortex -- specifically targeted to regions with maximal functional connectivity to the hippocampus -- caused increases in MTL/hippocampal theta power, while DLPFC stim caused decreases in hippocampal gamma power.

[Ethan Solomon @esolomon]

4/ TMS to the DLPFC caused frontolimbic increases in low-frequency (theta) power and temporal decreases in high-frequency (gamma/HFA) power.

[Ethan Solomon @esolomon]

Now out in @brainstimj from @KellerStanfordU and @boeslab! What does TMS do to the human brain? Using a combination of intracranial EEG and TMS, we published one of the deepest explorations of TMS-related change in human neurophysiology to date. 1/7 🧵https://t.co/vvcwAVE72t

[Ethan Solomon @esolomon]

3/ In 17 neurosurgical patients with intracranial electrodes, we gave single-pulse TMS and analyzed the ensuing neural activity to get a high-resolution picture of how TMS affects activity throughout the brain, including deeper structures like hippocampus, amygdala, and cingulate

[Ethan Solomon @esolomon]

2/ TMS is a powerful brain stimulation technique, but its effects have usually been studied with non-invasive EEG, which has limited spatial resolution and can't access deep structures beyond the cortical surface.

[Precision Neurotherapeutics Lab @ Stanford @PNTlabStanford]

Our work with @boeslab now out at @brainstimj! 👏

Using TMS w/ iEEG we show that single pulses evoke spectral responses throughout the brain, including deep brain structures such as hippocampus & cingulate https://t.co/FlInkGesaT

@StanfordBrain @Stanford_Neuro @UIowaNeuro 🧠⚡️

[Ethan Solomon @esolomon]

@psybalazs @US_FDA @MAPS To me, the fact that the study authors themselves made little/no effort to quantify the expectancy effect -- or even report basic data on it! -- is one of the most concerning things. Why is the onus on the public to try to impute the effect from other studies?

[Precision Neurotherapeutics Lab @ Stanford @PNTlabStanford]

🎉 We're excited to finally announce our lab's official name: Stanford Precision Neurotherapeutics Lab! 🧠🚀

Our website relaunch is now live 🌐 Check out our latest research and discoveries at https://t.co/IlOlpOUCI3

@StanfordBrain @StanfordMed #Neuroscience #StanfordScience

[Ethan Solomon @esolomon]

@RecoveryDoctor I've also seen some evidence that risk of agranulocytosis is actually on par with several of the SGAs.

[Ethan Solomon @esolomon]

Continue to be inspired by all of the amazing work @HannahGu15 has done in three years of @StanfordNeo fellowship!

[Ethan Solomon @esolomon]

Noa is an amazing scientist and Jefferson is an awesome place to do intracranial ephys! Go work with her!

[Noa Herz @Noa_Herz]

Interested in using intracranial recordings and stimulation in humans to study memory, and leveraging this knowledge to treat memory-related disorders like PTSD?
I am recruiting a postdoc to our emerging interdisciplinary team at @JeffersonUniv! RTs appreciated

[Ethan Solomon @esolomon]

@gershbrain Difference between believing these are true and asking if they can be alternatively explained by psychological phenomena following life-altering or traumatic events, like getting an organ transplant.

[Corey Keller @DrCoreyKeller]

Exciting times ahead in the lab! Anticipating valuable insights from behavior, invasive ephys, and video, as we deepen collaboration with @josef_parvizi & @scott_linderman. Thrilled to see @YuhaoHuangMD's vision unfold! 🧠 ⚡
https://t.co/wnBtqsYQzH @StanfordBrain

[Ethan Solomon @esolomon]

@DrLuisACenteno1 @AllenFrancesMD Does belief that schizophrenia is a "biological" disease need to be mutually exclusive with the idea that psychotherapy, in some cases, can be offered as effective treatment?

[Carolyn Rodriguez @CRodriguezMDPhD]

Check out @esolomon new research at Data Blitz @ACNPorg and all the exciting talks going on NOW! 11:30-1pm TM, Florida Ballroom #ACNP2023 👇👇👇