So a bit about the latest and greatest from the lab! Here we discovered the OAA family of lectins inhibit SARSCoV2 viral entry and characterized the mechanism of BOA and OAA mediated inhibition. https://t.co/lhGZjzxFBp
If this approach is as robust as these early results suggest, the impact on the molecular life sciences will be large. Not too long ago, a movie scene in which the hero asks a machine to create a protein with a custom function deserved major eye rolling. But now it’s happening.😳
Super excited to share my 1st first-author publication out today in @ScienceMagazine, in which we resurrect billion-year-old enzymes to study the evolution of Rubisco. Let me tell you how a 100 amino acid protein facilitated the rise of oxygenic life.
https://t.co/ZlXtteA8bw
So happy that this chemistry got the recognition it deserves. On a personal note super stoked for my friend and colleague Christian Tornøe who did the first copper catalysed reactions in the Meldal lab. Photo credit: Wouter Hogendorf
We keep on asking, #enzymes keep on giving! we asked an acylase to recognize 3 different amines on insulin and today we can share new strategy for enzymatic functionalization of native proteins #directedevolution#bioconjugation#merckchemistry https://t.co/viKwcfWaTC
Great opportunity for biophysics PhD students/early postdocs who are curious about drug development and working in the pharmaceutical industry: Novo Nordisk “Scientist of Tomorrow” – Biophysics and Formulation Symposium 2022! https://t.co/u3UzycYkzJ
Looking for a new job at the interface of Data Science, Molecular Modelling and biologics design? And a proven creativity and curiosity in getting most out of SAR data by visualization and ML-technologies? #drugdesign#biologics#cheminformatics https://t.co/j10XvlFyLn
Time for another pharmacology tweetorial, this time about the log-normal distribution and its importance to the interpretation, and aggregation, of assay data in drug discovery. 1/
Incredibly excited to share our paper ‘Somatic mutation rates scale with lifespan across mammals’ now published @nature.
https://t.co/a68IkkTt33
An illustrated & updated tweetorial… [1/24]
Interested in developing and applying next generation #machinelearning to #peptide design and prediction - we have multiple permeant positions at Novo Nordisk #machinelearning as well as summer intern
https://t.co/BvsQ5elymL
More on the intern position:
https://t.co/DFzS0LZyor
I'm excited to share our new paper - an incredible multi-year collaboration with the incomparable Philipp Korber (@KorberLab) driven by one of the most impressive graduate students I've had the pleasure of working with, Iris Langstein-Skora (@ILangstein) https://t.co/pfUfSgrk6Q