Gavin Ray

Work @PromptQL (@HasuraHQ)
OSS Contributor. I have a Postgres tattoo 🐘🎨

🔬🧪🧬Passion for Molecular Bio, Health, Fitness, Longevity
💪Aspiring Bodybuilder

[Gavin Ray @GavinRayDev]

Pretty cool 👀

[Gavin Ray @GavinRayDev]

@DadBodWorx My E2 would be single digits at 350 T + 350 Primo...

[Gavin Ray @GavinRayDev]

@BenBikmanPhD Thorough evidence of the contrary compiled in:

"Pleiotropic effects of GLP-1 receptor agonists — a narrative review of extra-metabolic outcomes in adults"

https://t.co/KXvMsMQr0V

[Gavin Ray @GavinRayDev]

@DrKERMD Reminds me of the guy who went to the Olympia and asked to check random bodybuilders' blood pressures:

https://t.co/Jzw9xiGeUw

One of them almost had her beat: 187/118

[Gavin Ray @GavinRayDev]

@DrKERMD > a blood pressure of 200/100 and a blood sugar of 500

Wow, she was really gunning for a high score, huh?

Besides: are you truly living if you're not walking around in a hypertensive crisis? 🤡

[Gavin Ray @GavinRayDev]

I just experienced something novel with LLM's I've never seen before:

For a single word, Gemini Argon 4 invented a term by combining a different language root with an English suffix:

> "банаl", from common Slavic "бана"-root with a Latin "l" suffix, for "banal"

[Gavin Ray @GavinRayDev]

@BowTiedArepa > What worked? I don't have a freaking clue. If it comes back I'll be more scientific for sure.

Hey, props for being honest at least.
Awesome that you feel better.

[Gavin Ray @GavinRayDev]

@DrKERMD @PuckReportNHL Close friend fainted due to vasovagal syncope after dropping something on his foot. Wild.

[Gavin Ray @GavinRayDev]

@NocturnalNelly So then how are you intending to discriminate whether any increase in muscle size is due to this drug or would have occurred regardless?

[Gavin Ray @GavinRayDev]

@NocturnalNelly This has some interesting literature behind it

Seems to be one of the few compounds that causes local effects:

"MID-35 acts locally within the injected muscle compartment rather than clearing through systemic circulation"

For science, will you do only one side of body?

[Gavin Ray @GavinRayDev]

@BevTchangMD https://t.co/BLvDV4bWWa

[Gavin Ray @GavinRayDev]

@RetailGaslight For those curious: https://t.co/L6OK8Petqf

[Gavin Ray @GavinRayDev]

@EsotericHarambe > "... blood work panels at every 12 weeks, continuous blood donation, blood glucose readings every day, blood pressure readings EOD, health supplement protocols we don’t skimp on"

If you don't have these RX'es are you truly BB'ing?

[Gavin Ray @GavinRayDev]

@GaintrustMikey I usually skip the gym when sleep-deprived too

But there is good news: @BradSchoenfeld recently looked at the impact of sleep deprivation on muscle

It turns out you can still make solid gains if you feel like lifting that day

https://t.co/eYOCKotXbD

[Brad Schoenfeld, PhD @BradSchoenfeld]

Does sleep really matter for muscle growth?

Our new critical review, just pubbed-ahead-of-print in SCJ, takes a deep dive into the evidence linking sleep and muscle hypertrophy.

Here’s what we found:

Severe sleep deprivation can reduce muscle protein synthesis and negatively affect hormones, strength, and training performance. Moreover, observational research links both short and excessively long sleep with poorer muscle health and greater sarcopenia risk.

But here’s the catch: there is surprisingly little direct evidence that habitual sleep duration actually affects resistance training-induced muscle growth. In fact, one of the few longitudinal studies found that sleeping ~1–2 hours less per night did not impair hypertrophy or strength gains over 5 weeks of resistance training in untrained men.

So, while adequate sleep almost certainly plays an important role in supporting recovery and training quality, we currently cannot prescribe a specific amount as “optimal” for maximizing hypertrophy. A reasonable starting point appears to be ~7–9 hours per night. However, individual sleep needs likely vary considerably based on the interplay between genetic predispositions and lifestyle factors.

Bottom line: The mechanisms suggest sleep matters, but we still need long-term controlled studies—especially in trained lifters—to determine how much it actually affects muscle growth.

https://t.co/lTNc9G8cWd

[Gavin Ray @GavinRayDev]

@shortniggarizz @DrCamRx My ex was an alcoholic. It caused all sorts of problems in her life.

I don't drink, not because I have anything against it -- I just don't enjoy it

Saying "just don't drink" makes it seem as if the effort involved is equal for everybody, when the truth is not so black and white

[Gavin Ray @GavinRayDev]

@bowtiedmeathead Upper/Lower twice a week was the split?

[Gavin Ray @GavinRayDev]

@tywoosley23 Creatine and GH tho

[Gavin Ray @GavinRayDev]

@RetailGaslight @Oxandrolonely @tonymission Have you considered taking IGF-1 directly a-la IGF-1 LR3 or similar?

I've been running it at 100-200mcg/day. When you're taking multiple things, you can't objectively point towards one thing as causative, though.

[Gavin Ray @GavinRayDev]

@Krysia830073 Any chance I could get the TG link? 👀

[Gavin Ray @GavinRayDev]

@finkd I use Muse models through https://t.co/kQTmmoUW3m web chat

Are these models available there?
Or only through https://t.co/57XsWNcmdr?

[Gavin Ray @GavinRayDev]

@BrandonLuuMD Wearables like these are the first step we need to enable the future:

Continuous biometric data stored, along with your health records, so that personalized AI can give you tailored health advice for preventative medicine