Adrian Gervais

PhD @casanova_lab, @InstitutImagine. @AgroParisTech, @UnivParisSaclay & @univ_paris_cite alumni. Auto-antibodies, viruses, innate immunity, IEIs🔬

[Adrian Gervais @grvsadrian]

Grateful to have had the chance to present part of my work @ESIDsociety, with over 2,400 attendees! It was an amazing experience connecting with scientists from around the world and having insightful discussions. Can’t wait for the next edition!

[Adrian Gervais @grvsadrian]

@ShenYingZhang1 Thank you SY for your mentorship!

[ESID @ESIDsociety]

The Phenocopies of IEI session at #ESID2024 features experts Steve Holland, @anne_puel, @BenHalePhD, Aude Magerus, Sophie Hambleton, and @grvsadrian exploring how similar phenotypes emerge from different genetic causes. #IEI #ESID

[Sébastien Nisole @SEBNisole]

Just published in @NatureComms!
We show that Usutu virus is the only mosquito-borne flavivirus to resist ISG20-mediated inhibition, thanks to a unique domain in its 3'UTR that protects its genome from degradation.
A project led by @JimZPhD at @IRIM_life.
https://t.co/X4Rqe8dWzh

[Jeremie Rosain @JRosain]

1/ Excited to report in @JExpMed more about the causes and consequences of human autoantibodies neutralizing type I IFNs through the study of a rare disease: https://t.co/lZb4RE79Js

[Eric Topol @EricTopol]

About 10% of people who develop severe Covid have autoantibodies to Type 1 interferon, which doesn't get diagnosed. Now there's a simple assay.
It's also relevant for other life-threatening viral illnesses, and these Abs exist in ~100 million people worldwide.
https://t.co/CUzaykgVac @PNASNews @grvsadrian @casanova_lab

[Adrian Gervais @grvsadrian]

We report here in @PNASNews a simple assay to detect human type I interferon (IFN-I) deficiency. This test could revolutionize the diagnosis and management of patients with autoantibodies against IFN-I and inborn errors of immunity (IEI) affecting the IFN-I pathway!

[Casanova Lab @casanova_lab]

1/ We are excited to share a simple yet powerful whole blood assay to detect human type I interferon (IFN) deficiency...

[Adrian Gervais @grvsadrian]

Thrilled to share my second first-author paper out in @JExpMed. We show that about 10% of severe tick-borne encephalitis cases are due to auto-Abs neutralizing type I IFNs. Thanks to all our wonderful collaborators!

[Casanova Lab @casanova_lab]

1/ We are excited to share our report in #JEM that about 10% of severe tick-borne encephalitis (TBE) cases, triggered by the TBE virus (TBEV), are due to pre-existing auto-Abs neutralizing type I IFNs (https://t.co/6PZrCTsB21).

[Nicolas Berrod @nicolasberrod]

🦟 5 cas d'infections à virus du Nil occidental ont désormais été rapportés dans le Var, et plus de 70 dans toute l'Europe (dont 8 décès).

L'infection, par piqûre de moustique, est généralement asymptomatique mais elle peut provoquer de rares formes neurologiques graves.

1/3

[Judith Aberle @AberleJudith]

West Nile virus season in full swing in Europe
Austria reports 7 West Nile virus infections after mosquito bites (Lower Austria, Burgenland), including 3 hospitalized with neurological symptoms. One imported from Hungary
Several others under investigation https://t.co/NM0QjesSdr

[Casanova Lab @casanova_lab]

The title tells it all !

Severe West Nile virus and Sars-CoV-2 infections in a patient with thymoma and anti-type I IFN antibodies https://t.co/bJGPlUYrMq

[Adrian Gervais @grvsadrian]

I was delighted to share my work about West Nile virus encephalitis at the @Encephalitis2023 in London! And this is an honor to be awarded with the best platform presentation🙏 I met great people in with outstanding scientific level. Thank you Ava and the team! 🧠🧑‍🔬🤩

[Encephalitis International @encephalitis]

#Encephalitis2023 is now underway. @encephalitisava & Dr Nick Davies are leading the first session.
Speakers include Dr Tarun Dua @WHO , Dr Sophia Michael, Dr Christine Strippel, @grvsadrian & Dr Tina Damodar.
Excited to hear what they have to say about #encephalitis research.

[Adrian Gervais @grvsadrian]

👏🙏🚀

[Casanova Lab @casanova_lab]

1/ We are excited to report in @Nature the discovery that human inborn errors of the alternative NF-κB pathway-dependent immunity underlie the development of auto-Abs neutralizing type I IFNs (https://t.co/TFUOnBPIFi).

[Adrian Gervais @grvsadrian]

I will have the great honor of presenting part of my PhD work at the @encephalitis 2023 meeting next December, in London. Thanks a lot for the amazing opportunity! 🤩

[Encephalitis International @encephalitis]

#WestNile virus #encephalitis will be the topic when @grvsadrian joins our panel of speakers at Encephalitis 2023.

Our annual conference, aimed at medical professionals of all levels, can be attended @RCPVenue #London or online in December.

Tickets 👇

https://t.co/fWfDBsaU1v

[Alessandro Borghesi @esiborghe]

Screening for auto-Abs neutralizing type I IFNs is key to design prevention strategies. Check out https://t.co/Xfl2CNP2dm @grvsadrian @BarzonLuisa @ShenYingZhang1 @casanova_lab @JExpMed

[Institut Imagine @InstitutImagine]

Félicitations à @casanova_lab pour leur nouvel article dans @JExpMed ! Après leur rôle dans les formes sévères de COVID et de grippe, ils éclairent le lien des autoanticorps avec les formes sévères d'encéphalites dues au Virus du Nil
@Inserm @APHP @univ_paris_cite

[Adrian Gervais @grvsadrian]

@esiborghe @casanova_lab shared pleasure, and I am beyond grateful for this collaboration 🙏

[Alessandro Borghesi @esiborghe]

One fantastic collaboration with @casanova_lab, @grvsadrian, @ShenYingZhang, and all the co-authors - just go through the thread to discover more !

[Casanova Lab @casanova_lab]

1/ We are excited to share our report in @JExpMed showing that about 40% of cases of #WestNilevirus (#WNV) encephalitis are due to pre-existing auto-Abs neutralizing type I IFNs, making WNV encephalitis the best understood human infectious disease (https://t.co/lqug2qZOMT).