Guido Serini

Cell adhesion dynamics, angiogenesis and cancer, University of Torino, Candiolo Cancer Institute - All opinions expressed are my own

[Cell @CellCellPress]

Now online! Ligand binding initiates single-molecule integrin conformational activation https://t.co/WTRxBTVTQs

[Giorgio Seano @GiorgioSeano]

Thrilled to announce our latest research just published in @NatureComms! We investigated how therapy induces therapy resistance via cell state transition and vessel co-option in glioblastoma. (1/11) https://t.co/ek1HdLCBg3 #GBM #btsm #Research

[Guido Serini @gserini]

Looking very much forward to my visit to @CIBIO_UniTrento of Thu July 20th, meeting and discussing with its scientists

[CIBIO - UniTrento @CIBIO_UniTrento]

We are glad to host "In search of normality: looking for molecular strategies to repair #cancer blood vessels" a seminar by @gserini

🗓️ July, 20th at 2.30pm
🏛️ Room A104, Povo 1
ℹ️ https://t.co/H7kNfkzlTp

#blood #bloodtumor

[eriksahailab @eriksahailab]

Now with pretty picture added. Delighted to announce the line-up for the 4th Crick International Cancer Conference @TheCrick
Great speakers, numerous short talk opportunities, and we've kept prices low. Hope to see you there! https://t.co/O7EeBKBJqp

[Guido Serini @gserini]

@SirioDupont @DMM_Unipd @UniPadova Congrats Sirio!

[Enrico Giraudo @GiraudoEnrico]

Our paper is now out!! Great and exciting collaborative work. Thank you all.
https://t.co/0l8tNow4YP

[Johanna Ivaska @johannaivaska]

Beautiful work from @gserini lab on how integrin antibodies and FAK modulate crosstalk between integrin endocytosis and fibrillar adhesion turnover in ECs. Beautiful imaging and unexpected observations 🤩 https://t.co/Pg5CnuzMqH

[Guido Serini @gserini]

@johannaivaska Thank you, Johanna!

[R. Wedlich-Soldner @RWedlichSoldner.bsky.social @RolandSoldner]

Check out our new @biorxivpreprint
on counteracting tetraspanner- and BAR domain - nanodomains that results in the formation of stable plasma membrane furrows:
https://t.co/CxDFZVGmKA

[Vineet Gupta 🧬🧫 @gupta__vineet]

Super interesting study showing a highly functional role of allosteric ally activated integrin bI/bA domain vs other domains!

[Serini Lab @adhynamic]

@LSAjournal Very pleased to share our latest effort to functionally disentangle β1 integrin activation and clustering: the extracellular βI domain is key! Great collab with @MJ_Humphries @humphrieslab @integrintraffic @wtccmr

[LifeScienceAlliance @LSAjournal]

@adhynamic @gserini @MJ_Humphries @integrintraffic @unito @wtccmr @CoulterBME https://t.co/wfe6y56dyY

[LifeScienceAlliance @LSAjournal]

Mana et al. show the extracellular headpiece βI domain is involved in conformationally active β1 integrin clustering, fibrillar adhesion formation, incorporation of soluble fibronectin dimers into fibrillar polymers, and extracellular matrix-dependent endothelial cell migration.

[Giorgio Seano @GiorgioSeano]

Very cool piece of literature on #GBM and #TME, great work of integration of knowledge from a large community!! Great job, @AndreasBikfalvi!! Honored to be part of it!

[Sara Zanivan @ZanivanLab]

Another fantastic collaboration with @DavidBryantLab! Have a read 👇🏻 #proteomics #MassSpectrometry

[Madeleine Oudin @MadeleineOudin]

Our first contribution to the cancer-nerve interaction field is out! We dissect the effect of sensory nerves on TNBC cell migration and metastasis and show that nerves drive changes in gene expression in tumor cells. https://t.co/IPES9jE9Tr

[Serini Lab @adhynamic]

📢A #postdoc position is open to join our lab to develop new exciting projects aimed at understanding how axon guidance cues and their receptors regulate #endothelial #celladhesion, #vascular permeability and #cancer cell invasion.

Thank you for sharing.

[Guido Serini @gserini]

📢A #postdoc position is open to join our @adhynamic lab to develop new exciting projects aimed at understanding how axon guidance cues and their receptors regulate #endothelial #celladhesion, #vascular permeability and #cancer cell invasion.

Thank you for sharing.

[Maurizio Giustetto @MaurizioGiuste1]

If you are interested in #Autism and #neurodevelopmentaldisorders you may enjoy reading our latest #research on #cdkl5 published with @SpringerNature in @npp_journal here https://t.co/cWZVAlqHXQ
@Telethonitalia
@AlberodiGreta
@FondazioneCRT
@CDKL5USA
@ITA_CDKL5_IVLC

[Fidel Lolo @FidelBio_83]

Check our last work on the role of caveolae in integrin mechanosensing, thanks to all contributing authors and @CaveoLab members for wonderful support over these years
https://t.co/ViAV5X19ih @eLife