Changliang Guo

[Changliang Guo @GuoChangliang]

3/3 COMET enables large-scale single-neuron network studies during natural behavior, with potential applications in learning, memory, social behavior, disease models, and longitudinal brain-wide circuit tracking.
https://t.co/OXciaInCOg
#neuroscience #miniscope

[Changliang Guo @GuoChangliang]

1/3 We built COMET (Cortex-wide Observational Miniature Epifluorescence Technique), a 3.75-g head-mounted mesoscope for cortex-wide, cellular-resolution calcium imaging in freely moving mice.
φ10-mm FOV, single-cell resolution.
https://t.co/OXciaInCOg
#neuroscience #miniscope

[Changliang Guo @GuoChangliang]

2/3 COMET combines wide-field optics, uniform excitation, compact electronics, and a dedicated analysis pipeline. In 5-min recordings, it can capture activity from >15,000 L2/3 neurons during natural behavior.
https://t.co/OXciaInCOg
#neuroscience #miniscope

[Changliang Guo @GuoChangliang]

3/3 COMET opens a route to longitudinal, cortex-wide single-neuron imaging during natural behavior, with potential applications in learning, memory, social interaction, and neurological disease models.
https://t.co/OXciaInCOg
#neuroscience #miniscope

[Science Advances @ScienceAdvances]

Scientists have developed an open-source microlens-array miniature microscope that can image the brains of freely moving mice with both a large field of view and cellular-level resolution. @NBIC_PKU @Orangeroad2017 https://t.co/LOJvfLWBMc

[Liangyi Chen @Orangeroad2017]

1/3 MIMAS is out in Science Advances: a 2.31-g open-source microlens-array miniscope for cellular-resolution imaging across ~4 × 4.5 mm² of dorsal cortex in freely behaving mice. https://t.co/tCtj8thGT8

[Weisong Zhao @weisong_zhao]

Out at @nature just now!

https://t.co/6E9s9rCPz8

We present #RIED, a new paradigm for excitation-free super-resolution microscopy.

We establish chemical super-resolution microscopy using electrochemiluminescence (ECL), chemiluminescence (CL), and bioluminescence (BL).
(1/n)

[Liangyi Chen @Orangeroad2017]

The formal announcement of Sino-France
2nd Joint Meeting on Biolmaging! A great symposium with a great lines of speakers! Thanks to @SalameroJean and Laurent Bourdieu for working together to make it possible.👏

[Changliang Guo @GuoChangliang]

@weisong_zhao Congratulations! Prof. Weisong Zhao.

[Liangyi Chen @Orangeroad2017]

Congrats to everyone who has come along this far to make it happen! I have also written a detailed behind-the-paper story, summarizing the difficulties and the long journey to leave a permanent mark on my project that has taken the longest to accomplish! https://t.co/N6C7jErKvL

[Liangyi Chen @Orangeroad2017]

Here is the research briefing: https://t.co/qP2f3NSHn0.

[Liangyi Chen @Orangeroad2017]

Our fourteen-year-old work is out in Nature Metabolism! Using zinc dye to image hundreds of insulin secretions within the intact islet, we reveal only a portion of islet b-cells exocytosis upon glucose stimulation (readily releasable b-cells).
https://t.co/dho6IbDqqd

[Changliang Guo @GuoChangliang]

@Orangeroad2017 Really brilliant work! Congratulations!

[Optica Publishing Group @OpticaPubsGroup]

Volume 48 Issue 24 of #OPG_OL is now live: https://t.co/MYPqXdeX3v

The featured image shows a diagram of a highly flexible integrated light-field endoscope. For details, see Su et al., https://t.co/HSAIChb8zN

[Weisong Zhao @weisong_zhao]

Out at @LightSciAppl just now!

Very happy to share a nice tool we recently developed, the #rFRCmetric, evaluating the super-resolution (SR) quality at the corresponding SR scale.

The upscaled resolvability of super-resolution imaging requires a more elaborate evaluation!
(1/n)

[Weisong Zhao @weisong_zhao]

It's a great pleasure for our recent work #SACDimaging to be selected as the cover article of Volume 17 Issue 9, September 2023
@NaturePhotonics

https://t.co/42yq7EXhVa

[Liangyi Chen @Orangeroad2017]

On my academic trip to Gottingen, I was delighted to meet Jorg and tour his department. Viewing the Great Man's Relics was also a fantastic experience!

[Liangyi Chen @Orangeroad2017]

A little advertisement for the third HuaiRou Forum, focusing on future technologies and talents. Here is the list of international speakers. We also have an equally good list of Chinese speakers. Welcome to join😀

[Nikon Microscope Solutions @NikonInst]

Researchers introduce a new method for high-resolution light field #Microscopy #LFM, demonstrated for fast live cell imaging of single cells with resolution between 300-700 nm in each dimension. Learn more: https://t.co/wkPmWum2f7

[Changliang Guo @GuoChangliang]

@NikonInst Thanks for sharing!