Top Tweets for #AACRepmet20
Read the recently published abstracts from the @AACR virtual Special Conference on Epigenetics and Metabolism: https://t.co/rQA5DG6AuK #AACRepmet20
Loss of #EZH2 reprograms branched-chain amino acid #metabolism to drive leukemic transformation.
@JianXuLab @CRI_UTSW #AACRepmet20
https://t.co/sRw6KAYNza
#Metabolomics performed on pancreatic juice from patients with #PDAC identifies #metabolic variables correlating with outcome and #TILs. This paper earned a #CIRReviewerStar ⭐
#metabolites #lactate #glycolysis #GLUT1 #PD1 #AACRepmet20
https://t.co/CaheAmkiYX
Global regulation of the histone mark H3K36me2 underlies epithelial #plasticity and metastatic progression.
@PennMedicine #Cancer #Epigenetics #Metastasis #AACRepmet20
https://t.co/hIZkYAfkAJ
Epigenetic switch–induced viral mimicry evasion in #chemotherapy-resistant #BreastCancer.
@MatLupien @pmcancercentre #epigenetics #TNBC #AACRepmet20
https://t.co/YWK9AQbTWj
Day 2 of #AACRepmet20 kicks off with a presentation by Alexandre Puissant.
Read his article: The folate cycle enzyme MTHFR is a critical regulator of cell response to #MYC-targeting therapies.
@LabPuissant #Metabolism
https://t.co/r9fWMimUlm
Tissue-resident memory #Tcells are associated w/ #GastricCancer prognosis. They rely on #FattyAcid #oxidation for survival. #PDL1 blockade promoted #lipid uptake by the cells. So, #metabolic #reprogramming might enhance #antitumor #immunity. #AACRepmet20 https://t.co/gGrhBasM0V
A #glioma #stemcell specific #superenhancer promotes polyunsaturated fatty acid synthesis to support #EGFR signaling.
@UCSDHealth @UCSDMedSchool #AACRepmet20
https://t.co/O4aWLBXUOD
We're watching #AACRepmet20 Plenary Session 3, chaired by Kathryn E. Wellen.
Read her paper: Acetyl-CoA #metabolism supports multi-step #pancreaticcancer development.
@WellenLab @acarrer @PennMedicine
https://t.co/yreng4pwZt
Top Influencers of #AACRepmet20: @CD_AACR @ElizSMcKenna @ElisaEspinet @DKFZ @hi_stem_lab @mcgillu @DFKZ More 📊 https://t.co/CjIkHIHouK
G34W mutation in the #Histone 3 variant H3.3 promotes growth and impedes differentiation of osteoblast-like mesenchymal progenitors in giant-cell tumor of bone.
@ClaudiaKleinman @mcgillu #Sarcoma #Epigenetics #Osteoclastoma #AACRepmet20
https://t.co/dGN0KP6SmU
Now published and presented at #AACRepmet20:
Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin.
@ElisaEspinet @DKFZ @hi_stem_lab #PancreaticCancer #Epigenetics
https://t.co/MMyRy9NaMB
Now published and presented at #AACRepmet20:
Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin.
@ElisaEspinet @DKFZ @hi_stem_lab #PancreaticCancer #Epigenetics
https://t.co/MMyRy9NaMB
#Tumor #metabolism leads to #adenosine production. Adenosine #A2B receptor on #immunosuppressive APCs inhibits #antitumor #Tcells, promoting tumor growth. Targeting adenosine A2B receptor may enhance immunotherapy. #AACRepmet20
https://t.co/9pjnS6gpbT
We're watching #AACRepmet20 and tweeting related articles:
Epigenetic suppression of transgenic T-cell receptor expression via gamma-retroviral vector methylation in adoptive cell transfer therapy.
@UCLAJCCC #epigenetics #immunotherapy
https://t.co/uORPqUsKVK
We're watching #AACRepmet20 and tweeting related articles:
Epigenetic suppression of transgenic T-cell receptor expression via gamma-retroviral vector methylation in adoptive cell transfer therapy.
@UCLAJCCC #epigenetics #immunotherapy
https://t.co/uORPqUsKVK
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