#Axonal - Twitter Hashtag

10 months ago

#Research by Christoph T. Block et al. investigated saltatory #axonal conduction in the avian #retina 👁️ 🐦 📜 Read the study here: https://t.co/Hls1Bi4Kkl

JPhysiol's tweet photo. #Research by Christoph T. Block et al. investigated saltatory #axonal conduction in the avian #retina 👁️ 🐦

📜 Read the study here: https://t.co/Hls1Bi4Kkl https://t.co/lWnXsmCfMy

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Albert Vamanu @VamanuAlbert

over 1 year ago · Camberwell

Mechanically, #TBI results from external forces causing rapid acceleration-deceleration or direct impact (coup-contrecoup), leading to primary #injuries such as #contusions, #axonal #shearing, and #vascular #damage. At the molecular level, the initial #trauma triggers a cascade of secondary injury mechanisms, including #excitotoxicity (excessive #glutamate release), oxidative stress (free radical production), mitochondrial dysfunction, and #neuroinflammation (activation of #microglia and release of pro-inflammatory #cytokines). These processes insult the blood-brain barrier, enhance neuronal cell death, and impair synaptic function. Anatomically, TBI can show focal #lesions (hematomas) or diffuse injuries (diffuse axonal injury), affecting regions like the cortex, hippocampus, or brainstem, depending on the injury's severity and location. The heterogeneity of TBI ranging from mild concussions to severe penetrating injuries creates variations in #clinical #outcomes, making it a challenging condition to diagnose and treat effectively.

VamanuAlbert's tweet photo. Mechanically, #TBI results from external forces causing rapid acceleration-deceleration or direct impact (coup-contrecoup), leading to primary #injuries such as #contusions, #axonal #shearing, and #vascular #damage. At the molecular level, the initial #trauma triggers a cascade of secondary injury mechanisms, including #excitotoxicity (excessive #glutamate release), oxidative stress (free radical production), mitochondrial dysfunction, and #neuroinflammation (activation of #microglia and release of pro-inflammatory #cytokines). These processes insult the blood-brain barrier, enhance neuronal cell death, and impair synaptic function. Anatomically, TBI can show focal #lesions (hematomas) or diffuse injuries (diffuse axonal injury), affecting regions like the cortex, hippocampus, or brainstem, depending on the injury's severity and location. The heterogeneity of TBI ranging from mild concussions to severe penetrating injuries creates variations in #clinical #outcomes, making it a challenging condition to diagnose and treat effectively.

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Neural Cell News

@NeuralCell

almost 2 years ago

Kick back with a new #review this weekend. 📖 @UnivAveiro scientists summarize the intrinsic mechanisms driving #axonal regeneration, interplay between these mechanisms, and barriers to axonal regeneration. 👀 Find it in @TrendsNeuro: https://t.co/3QObYKH8Qr

NeuralCell's tweet photo. Kick back with a new #review this weekend. 📖

@UnivAveiro scientists summarize the intrinsic mechanisms driving #axonal regeneration, interplay between these mechanisms, and barriers to axonal regeneration.

👀 Find it in @TrendsNeuro: https://t.co/3QObYKH8Qr https://t.co/xeYIqIAGPJ

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University of Toronto Neurosurgery @UofTNeuroSurge

almost 2 years ago

@AristotelisKal1 @gelarehzadeh and Dr. Paul Kongkham’s recent study reveals direct #axonal connectivity between the #precuneus and temporal pole via the CB-V pathway. Read more about their findings in the Human #BrainMapping Journal: https://t.co/PrpF6OdwE5

UofTNeuroSurge's tweet photo. @AristotelisKal1 @gelarehzadeh and Dr. Paul Kongkham’s recent study reveals direct #axonal connectivity between the #precuneus and temporal pole via the CB-V pathway.

Read more about their findings in the Human #BrainMapping Journal:

https://t.co/PrpF6OdwE5 https://t.co/bO4QNDt3DC

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Neural Cell News

@NeuralCell

almost 2 years ago

Dalian Medical University researchers uncovered the molecular mechanisms underlying the contribution of WD repeat domain 45 (WDR45) deficiency to #axonal degeneration. 📚 Read about their findings in @MolNeuro! https://t.co/nvThQmQbGm

NeuralCell's tweet photo. Dalian Medical University researchers uncovered the molecular mechanisms underlying the contribution of WD repeat domain 45 (WDR45) deficiency to #axonal degeneration.

📚 Read about their findings in @MolNeuro!

https://t.co/nvThQmQbGm https://t.co/tU0tqRTUoM

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Molecular Neurodegeneration @MolNeuro

over 2 years ago

'NMNAT2 supports vesicular #glycolysis via NAD homeostasis to fuel fast #axonal transport' Sen Yang, Zhen-Xian Niou... Hui-Chen Lu @IndianaUniv @IU_GillCenter #GlutamatergicNeurons https://t.co/rIjnkM4BTK

MolNeuro's tweet photo. 'NMNAT2 supports vesicular #glycolysis via NAD homeostasis to fuel fast #axonal transport'

Sen Yang, Zhen-Xian Niou... Hui-Chen Lu @IndianaUniv @IU_GillCenter #GlutamatergicNeurons

https://t.co/rIjnkM4BTK https://t.co/bD9KFdF9gL

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ZEISS Microscopy @zeiss_micro

almost 3 years ago

Watch how #axonal growth cones explore the environment to determine the direction of #neural growth. Image courtesy: M. Kengaku, Kyoto University, Kyoto, Japan. Imaged with ZEISS Lattice Lightsheet 7. Read the full story of this acquisition here: https://t.co/j1axCaQLg9

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Luka Cicin-Sain (cicin-sainlab.bsky.social) @CicinSain_Lab

about 3 years ago

#IHW2023 Greg Smith Keynote talk on mechanisms of #HSV-1 #axonal #transport. Proposes that Kinesin-I (K-I) gets packaged into virions by gE/gI resulting in motility, but pUL37 R2 represses retrograde transport by K-I, resulting in anterograde transport. Lots of audience questions

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Molecular Neurodegeneration @MolNeuro

about 3 years ago

New publication for our ALS Review Series Collection! 'Looking for answers far away from the soma—the (un)known #axonal functions of TDP-43, and their contribution to early NMJ disruption in #ALS' @ArielIonescu @AltmanTopaz @LabPerlson @TAUMedFaculty https://t.co/gwr1ZTkEqR

MolNeuro's tweet photo. New publication for our ALS Review Series Collection!

'Looking for answers far away from the soma—the (un)known #axonal functions of TDP-43, and their contribution to early NMJ disruption in #ALS'

@ArielIonescu @AltmanTopaz @LabPerlson @TAUMedFaculty

https://t.co/gwr1ZTkEqR https://t.co/8mqsr54mRg

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Mario Del Rosario @_mariod

over 3 years ago · Oeiras

@christlet as expected, amazed us with gorgeous #microscopy to elucidate the #axonal and #presynaptic actin nano-structures, better tags for super-resolution microscopy, @BrunoCombettes from @AndorTechnology presenting the versatile Dragonfly 600 #celldyn2023 2/2

_mariod's tweet photo. @christlet as expected, amazed us with gorgeous #microscopy to elucidate the #axonal and #presynaptic actin nano-structures, better tags for super-resolution microscopy, @BrunoCombettes from @AndorTechnology presenting the versatile Dragonfly 600
#celldyn2023 2/2 https://t.co/Fqzm0SBorI

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Annovis Bio @AnnovisBio

almost 4 years ago

High levels of #neurotoxic proteins disrupt #axonal transport and lead to #neurodegeneration. At $ANVS, we believe that targeting these proteins simultaneously is the key to treating neurodegenerative diseases.  Read more https://t.co/1cwwiKglFD

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Saudou Frédéric @SaudouLab

almost 4 years ago

@FtimaMesaHerre1 If you are interested to study the cell biology of #Huntingtonsdisease and develop innovative therapies based on #axonal transport and energy metabolism please see my lab @GINeuroGrenoble

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The EMBO Journal @embojournal

almost 4 years ago

How do proteasomes affect stress resilience of damaged #motorneurons? Sumiko Kiryu-Seo, Hiroshi Kiyama et al @NagoyaUniv find them to dismantle barriers that block #axonal entry of #mitochondria https://t.co/MItTtS6jtY

embojournal's tweet photo. How do proteasomes affect stress resilience of damaged #motorneurons?
Sumiko Kiryu-Seo, Hiroshi Kiyama et al @NagoyaUniv find them to dismantle barriers that block #axonal entry of #mitochondria
https://t.co/MItTtS6jtY https://t.co/tqpPGhPntQ

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Jerome Staal @NeuroStaal

about 4 years ago

Interesting study identifies a conserved endocytic clearance mechanism in the #AxonInitialSegment that maintains #neuronal polarity by reinforcing #axonal and dendritic compartment membrane boundaries. https://t.co/SNKyKSGGej

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Hybrigenics Services

@HGX_services

about 4 years ago

The role of FIGNL1 in #axonal navigation? Performing our Ultimate #Y2H service for the lab of Dr. Coralie Fassier @filodelbene @Sorbonne_Univ_, we are proud to have supported their research in dynein transport velocity during #AxonNavigation. https://t.co/uy7IVt5xMI @JCellBiol

HGX_services's tweet photo. The role of FIGNL1 in #axonal navigation? Performing our Ultimate #Y2H service for the lab of Dr. Coralie Fassier @filodelbene @Sorbonne_Univ_, we are proud to have supported their research in dynein transport velocity during #AxonNavigation. https://t.co/uy7IVt5xMI @JCellBiol https://t.co/Aw6DJVR01a

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Peptide Sciences @PeptideScience

about 4 years ago

#Peptide #Research for #Neurocognitive Improvement. “#Cortical thickness and #subcortical volume are shrinking 0.5–1% annually as a morphological sign of #cognitive decline with #plaques and #axonal #degeneration.” #Peptides #Dihexa #TB4 #Selank #Semax https://t.co/fFUQvWApAK

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stmpub @STMPUB

about 4 years ago

#pharmacological #axonal #stroke #neuronalinjuries #nrr #openaccess #perspective [Title: Nogo-A receptor internalization by cyclic adenosine monophosphate in overcoming axonal growth inhibitors after stroke] https://t.co/35rNReGKxB

STMPUB's tweet photo. #pharmacological #axonal #stroke #neuronalinjuries #nrr #openaccess #perspective [Title: Nogo-A receptor internalization by cyclic adenosine monophosphate in overcoming axonal growth inhibitors after stroke]
https://t.co/35rNReGKxB https://t.co/p2oTXFLeMq

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LIMES Institute Bonn @LIMES_Bonn

over 4 years ago

A quantitative model of #sporadic #axonal #degeneration in the #Drosophila #visual system @SfNJournals @GTavosanis @UniBonn @DZNE_en #neurodegenerative #diseases https://t.co/0usFwWIYOM

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Idylle @IdylleLabs

over 4 years ago

#ResearchTech YOU like😍 a #BLOG post by🙏Helene Vitet who shares this #Microfluidics #ResearchTool it recreates a physiological neuronal network to control the neuronal connectivity & function👏 https://t.co/AEvZSq4tR6 #Axonal #Dendritic #Mitochondria #Glutamate #BDNF #Synapse

IdylleLabs's tweet photo. #ResearchTech YOU like😍

a #BLOG post by🙏Helene Vitet who shares this #Microfluidics #ResearchTool
it recreates a physiological neuronal network to control the neuronal connectivity & function👏
https://t.co/AEvZSq4tR6
#Axonal #Dendritic #Mitochondria #Glutamate #BDNF #Synapse https://t.co/fFwfX2L3Bw

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FEBS Letters @FEBS_Letters

over 4 years ago

▪Mutations in the nuclear matrix protein MATR3 are associated with #neuromuscular disease ▪This study finds that in #Drosophila models, the knockdown of genes involved in #axonal transport enhances the toxicity of mutant MATR3 ➡https://t.co/hLn1kgv1rv #Dros22 #motorneurons

FEBS_Letters's tweet photo. ▪Mutations in the nuclear matrix protein MATR3 are associated with #neuromuscular disease

▪This study finds that in #Drosophila models, the knockdown of genes involved in #axonal transport enhances the toxicity of mutant MATR3

➡https://t.co/hLn1kgv1rv

#Dros22 #motorneurons https://t.co/ML9tJScRZf

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