Top Tweets for #BAG3
>12% of adult & pediatric #cancer #patients w/ #chemotherapy-induced #cardiomyopathy (CCM) had PGVs in #BAG3, #LMNA, #MYH7, #TCAP, #TNNT2, #TTN.
#Patients treated w/ #anthracycline or #trastuzumab
Though recovery occurred, final LVEF was more depressed in #patients w/ #TTN PGVs
#Universal #cardiomyopathy #germline #genetictesting in all #cancer #patients prior to #anthracycline or #trastuzumab tx?
"...to define [#cancer] #patients...w/ high risk for CCM through #genetictesting...assess the efficacy of prophylactic cardioprotective drugs & treatment regimens to reduce CCM while providing effective #cancertherapy."
#access #reducedisparities #germlinetesting #precisionmedicine #precisiontherapy #clinicaltrials #precisionprevention
https://t.co/cMztpIr9aL #DrPabloGarciaPavia et al. @CircAHA
![EdEsplin's tweet photo. >12% of adult & pediatric #cancer #patients w/ #chemotherapy-induced #cardiomyopathy (CCM) had PGVs in #BAG3, #LMNA, #MYH7, #TCAP, #TNNT2, #TTN.
#Patients treated w/ #anthracycline or #trastuzumab
Though recovery occurred, final LVEF was more depressed in #patients w/ #TTN PGVs
#Universal #cardiomyopathy #germline #genetictesting in all #cancer #patients prior to #anthracycline or #trastuzumab tx?
"...to define [#cancer] #patients...w/ high risk for CCM through #genetictesting...assess the efficacy of prophylactic cardioprotective drugs & treatment regimens to reduce CCM while providing effective #cancertherapy."
#access #reducedisparities #germlinetesting #precisionmedicine #precisiontherapy #clinicaltrials #precisionprevention
https://t.co/cMztpIr9aL #DrPabloGarciaPavia et al. @CircAHA](https://pbs.twimg.com/media/G3oyKG8WgAA_s3q.jpg)
Time to lift a few weights? Study in @CurrentBiology shows #strengthtraining activates cellular waste disposal which is essential for maintaining our tissues and organs, preventing #heartfailure and some nerve diseases. It’s all about #BAG3. https://t.co/zm5X3QwvVc
✨Commissions Open✨ come get a trinket from this little Crow! 🐦⬛ #commissionart #commissionsopen #art #ocart #dnd #bag3

❤️The July issue is out❤️Read about how a common #BAG3 variant is #cardioprotective, how #calcineurin promotes the #brokenheart syndrome, the transition of #foam #macrophages to an inflammatory state in #atherosclerotic plaques and much more! https://t.co/bS91t9OQo2

News and Views by Xiao Wang and @kiranmusunuru @PennCVI on the recent study by @Juan_PerBer et al. presenting an in-depth functional analysis of a common variant in the #BAG3 associated with lower incidence of #HeartFailure|
https://t.co/fEILLZhVBO
👉https://t.co/cu6EtX1ly3
Join us today at noon at Main Baylor in Room M112 for the #JTWillersonCVSeminarSeries! We are excited to host @jonathankirk from @LoyolaChicago. Learn about #sarcomere protein quality control at #BAG3 and enjoy some light bites!

We are excited to host @jonathankirk from @LoyolaChicago as this week's #JTWillerCVSeminarSeries invited speaker. Join us Wednesday at noon at Main Baylor in Room M112 and learn about #sarcomere protein quality control and #BAG3.

Get ready for @JonathanKirk of @LoyolaChicago @ the #JTWillersonCVSeminarSeries Wed 10.19 @12pm! Venue @bcmhouston M112. Learn the latest about ❤️ #sarcomere protein quality control& #BAG3. @texas_heart @UTHHeart @UTHEPHEART @BCM_CTSurgery @BCMHeart @BaylorGenetics #cardiotwitter

Check out this great read + Behind the Bench podcast from @jonathankirk @Dr_TommyMartin & co-authors on #BAG3 expression and #sarcomere localization in the human heart are linked to HSF-1 and are differentially affected by sex and disease https://t.co/pPqtKCdXoF
Journal of Physiology and Biochemistry @JPBY_official
BAG3 protects chondrocytes against lumbar facet joint osteoarthritis by regulating autophagy and apoptosis
#Lumbar_facet_joint #Osteoarthritis #BAG3 #Apoptosis #Autophagy
https://t.co/21vDZeYkqE

Proud mentor, as @Tom_Martin315 successfully defended his dissertation and is now Dr. @Tom_Martin315! Going to miss him as he moves on from @LoyolaChicago, but can't wait to see what he accomplishes next! #BAG3 #AcademicChatter #CardioTwitter #PhDone

BEHIND THE BENCH Ep 10: Meet @Tom_Martin315, a trainee @LoyolaHSC. @matrixville & @char_lab get the scoop about life in The Kirk Lab, #BAG3 protein expression in sarcomeric proteins in #HF, and what to call @jonathankirk if he's about to get hit by a bus https://t.co/GihQt7T9Yg

Nearly finished grad student @Tom_Martin315 was interviewed by @char_lab & @matrixville for @ajpheartcirc's Behind the Bench podcast. He talked about his recent #BAG3 work, his path to a PhD, and his dream of working at an Italian restaurant! Listen here: https://t.co/YeZfmZXhQd
Proposed cancer therapeutic JG-98, which disrupts the interaction of #BAG3 and HSP70, has significant cardiotoxic effects, shows @Tom_Martin315's recent paper from the lab. #CardioOnc #autophagy #sarcomere https://t.co/x0QUv5ZyAj
Just dropped on @jclinicalinvest, our review on #BAG3 in heart and cancer. Our third BAG3 paper this year - with more to come! #cardioOnc #yearofthebag https://t.co/NjNWhLYVXg
#podcast Dr. Marc Semigran #Renovacor on #BAG3 associated #DilatedCardiomyopathy #DCM & the cardiac #GeneTherapy in development to treat this genetic disease. Lead asset REN-001 modified virus will specifically target the cardiac muscle cells #raredisease https://t.co/UGZYSAEN2n
Only 19 out of 51 evaluated genes from clinical DCM tesing panels were appraised as having a high evidence for validity https://t.co/7ThePgyNTq #AHAJournals @CSHeartResearch @drjamesware @NajimLahrouchi @jpvantintelen @tomlumbers @ProtonotariosA @roddywalsh @murray_bdye

Check out our new paper in JCB where we showed that loss of #BAG3 leads to #ciliogenesis and reduced EMT in #Glioblastoma and #BreastCancer cells https://t.co/0tPPvjLW1e
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