Top Tweets for #CascadeTesting
@NiteckiRoni @MDAndersonnews highlights how streamline medically directed #cascadetesting for #BRCA carriers leads to ⬆️ familial compliance of follow through 🧬 testing by family members. Scaled implementation takes time. HOW we deliver #gyncancancer care matters!
A microsimulation model showed that #cascadetesting lowered #colorectalcancer cases by 61% and deaths from colorectal #cancer by 78.5%, showing how much testing can help family members of those with #Lynchsyndrome newly diagnosed with colorectal cancer ⤵
https://t.co/C4V7ielN3W
Thank you @HeartDocSadiya for a great presentation raising awareness to #VUS & #CascadeTesting in the context of #ReturningofResearchResults supported by powerful story from #patientrepresentative Alexandra @nih_nhlbi workshop session 2 w/ chair @iftikhar_kullo
Achille Manirakiza, MD presents another cool poster on identification of #geneticmutations in cancer patients and communication strategies to disclose this info to family members for #cascadetesting.
@avmanirakiza @folopade @UChicagoHemOnc @uchicago_obgyn @UCCancerCenter
#LynchSyndromeAwarenessDay #PublicServiceAnnouncement
>90% of individuals w/ #LynchSyndrome don't know they have it
...underscoring the recommendation for #universal #germlinetesting of all #patients w/ #colorectalcancer & #cascadetesting for their families
https://t.co/qaDt5TeJiW
https://t.co/tFSemI4b2i @JCO_PO @Invitae
https://t.co/wa8YmWUWs3
@JCO @VivekSubbiah @Dr_R_Kurzrock
#access #genetictesting #reducedisparities #CRC #precisionmedicine #precisiontherapy #clinicaltrials #precisionprevention #ColorectalCancerAwarenessMonth
@FightCRC @CGAIGC @CCAlliance @ColonCancerCoal
@ColonCancerFdn
#PublicServiceAnnouncement -
90% of individuals w/ #LynchSyndrome don't know they have it (https://t.co/O2Q0bWJT0q, h/t @HHampel1), underscoring the recommendation for #universal #germlinetesting of all #patients w/ #colorectalcancer & #cascadetesting for their families
https://t.co/wa8YmWUWs3 @VivekSubbiah @Dr_R_Kurzrock
https://t.co/tFSemI4b2i @Invitae
#access #genetictesting #reducedisparities #CRC #precisionmedicine #precisiontherapy #clinicaltrials #precisionprevention #ColorectalCancerAwarenessMonth @FightCRC @CGAIGC @CCAlliance @ColonCancerCoal @ColonCancerFdn
I could not agree more! The best #cancer treatment is prevention and #genetic knowledge is necessary to identify additional risks - for that patient and their families #GeneticTesting #cascadetesting
Universal Germline and Tumor Genomic Testing Needed to Win the War Against Cancer: Genomics Is the Diagnosis | Journal of Clinical Oncology https://t.co/ZAeRzyGzys
If your patient carries a a pathogenic mutation - what's your role in helping to identify family members who may also be at risk? Guidance on how to approach relatives
https://t.co/c1QKR6tp6s
#genetics #womenshealth #cascadetesting
In our latest blog, we explore the barriers to cascade testing and how access to multi-gene analysis, such as next-generation sequencing (NGS), can help detect pathogenic variants early. Read more: https://t.co/MujQNuMRTw
#HereditaryCancer #CascadeTesting #CancerPrevention #NGS
The results are in! Families do communicate with relatives about genetic testing results. #hereditarycancer #geneticcounseling #cascadetesting https://t.co/1DOsV2pNc4
#CascadeTesting can be an important tool for identifying individuals who have an elevated #cancerrisk. If doctors find that someone’s cancer is related to a harmful mutation, close family members can then be tested for that same mutation. Learn more at https://t.co/lZMWBQjCzK.
This is cascade testing and the only way to ensure the family gets an accurate and complete diagnosis. Please don’t shy away from testing. Spread awareness. You can truly change lives. Share this now. #cascadetesting #genetics #fragilexsyndrome #autism #inherited #fragilexindia
#Germline #genetictesting essential for #cancer care
-#TargetedTherapies, #PARPi, #ICIs
-#SecondaryPrevention
-#CascadeTesting for family
1.3M #patient study, % #patients w/ #germlinetesting:
#ovariancancer (38.6%)
#breastcancer (26%)
#endometrialcancer (6.4%)
#pancreaticcancer (5.6%)
#colorectalcancer (5.6%)
#prostatecancer (1.1%)
#lungcancer (0.3%)
Rec'd for 100% of #ovarian, #pancreatic, #CRC, #breastcancer (@ASBrS) #patients
Large number of #patients w/ #cancer that still need #germlinetesting...
@AllisonKurian @StanfordMed @ASCO #ASCO23 @Invitae
Cascade #genetictesting signficantly lower in Black (11.9%) vs White (21.7%) #patients, and low uptake persisted for both groups after no-charge #cascadetesting program was introduced.
Barriers to #cascade #genetictesting for all #patients, including historically underrepresented & underserved populations, need to be identified and eliminated, for #access to #precisionprevention.
@NawalKassem et al. @IUMedSchool & @Invitae #PreventiveMedicine @ElsevierConnect
https://t.co/RuObjZtU0F
Are at-risk relatives being tested after a family member's positive #exomesequencing? What can be done to improve uptake of #cascadetesting https://t.co/vZI2hQbJ93
"#RacialDisparities in #cascadetesting for #cancerpredisposition genes"
"...marked #racialdisparity in...#cascadetesting for #cancerpredisposition...cost...is not the primary driver of disparate rates." @NawalKassem @IUMedSchool @Invitae
Preprint-https://t.co/Y0L8psxmrb
From U of C's Monogenic Diabetes Registry: participant experiences on obtaining correct diagnosis and treatment for #MODY and perceptions on disclosure of genetic results to family members. What can we learn to improve #cascadetesting in #MonogenicDiabetes?https://t.co/uKpPkM1aiS
Informational needs are dynamic and vary amongst individuals in families with pathogenic BRCA variants #HBOC #personalizedcare #cascadetesting https://t.co/YygTwvYw8R
@FASinicropeMD describing a direct-contact study with @HHampel1 to improve family member #cascadetesting uptake in NGS diagnosed germline PV carriers #insight2022 #lynchsyndrome
#UPDATE Just reaffirmed! The latest recommendations on how to inform relatives of patients about potential disease-causing mutations https://t.co/NDs7acdBDM #BRCA #cascadetesting #genetics #ObGyn #medtwitter
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