Top Tweets for #IntegraSE
Scientists at the Earlham Institute are investigating the potential for #integrase-based tools to influence #plantroot systems' response to external conditions.
https://t.co/Bv4qKYDCEI
Treatment Emergent #Dolutegravir #Resistance Mutations in Individuals Naïve to #HIV-1 #Integrase #Inhibitors: A Rapid Scoping Review
by Shafer et al:
👉https://t.co/qVqxkchCe7
#antiviralresistance #mutations
14/ In #PASTE Prime Editing creates the landing site so that an #integrase can come in and insert a new segment of DNA. Then the DNA repair machinery will kick in an repair the mismatch in the DNA.
More #phage curiosity -2 related phages likely have #integrase at a location (based on clustering, alignment of related, better studied phages and hmm screening) - but they're split into pieces. Are there examples of split/mulit-part integrase?
#microbiology #bioinformatics
El Delegado Territorial de @EmpleoJunta @AAGustinV asiste a la Inauguración de la Semana del Grupo Social @ONCE_oficial en Andalucía
Una exhibición de perros guía ha mostrado la importancia que tienen para la #movilidad, autonomía y #seguridad de las personas ciegas
#IntegraSE
Congratulations to Dr. Jennifer Nemhauser and her team at @UWBiology on their new @NatureComms paper! 🎉
It describes a newly developed #integrase toolbox to record #GeneExpression during plant development. 🧰
Learn more: https://t.co/bTmu3BVo2S
Here you have the crystal structure of the catalytic core of HIV integrase in complex with a small molecule inhibitor (PDB code: 4CJE)
Rendering by @fenguita made with #proteinimager
https://t.co/PWluAUX9DL
#molecularart #HIV #AIDS #integrase #treatment #genome #cadd
Different Pathways Conferring #Integrase Strand-Transfer #Inhibitors Resistance
Richetta and colleagues describe the mode of action of INSTIs and some typical resistance #mutations, such as #substitution and #insertion mutations.
Check it here:
👉https://t.co/SLBnp7iSeg
Here comes another, #Twin_PE, for performing diverse precise editing job.
#CRISPR #Cas #Integrase #dual_pegRNA
Today we report in @biorxivpreprint twin prime editing, a variant of prime editing that enables in human cells targeted large DNA deletion and replacement, as well as gene-sized integration and inversion when combined with site-specific recombinases. 1/9
https://t.co/z03e338cga
...curious to know what the C-terminal domain of HIV-1 integrase is capable of?
Look here! :)
@frances54442526
#HIV #integrase #TAR #RNA #Tat #biochemistry
https://t.co/mj7w3UjCAC
The HIV-1 Integrase C-Terminal domain induces TAR RNA structural changes promoting Tat binding. https://t.co/YeC1b0KSg3 #bioRxiv
Congratulations @Cecilia_Rocchi for winning the RNA 2021 Poster Award 👏from @RNASociety!
#TAR #Integrase #Tat #HIV #LoveRNAworld
our results will be soon online! 🤞
5 June marked 40 years since the first five cases of #HIV were reported by the CDC.
Continuing the fight.
#sequencing #HIVDR #integrase
Find out more here https://t.co/EVbVlW8mg6
We're thrilled to announce that we've launched several upgrades to our Exatype Sanger platform for HIV drug-resistance reporting. Read more: https://t.co/np0HVVu35D
#hivaids #resistance #sequencing #hiv #integrase
#Integrase #Inhibitors stop #HIV from making copies of itself by blocking a key #protein that allows the virus to put its DNA into the healthy cell's #DNA. They're also called integrase strand transfer inhibitors (#INSTIs).
Any chance you could help break down this exchange in the $SGMO R&D day Q&A last december for me? I'd love to understand this better. TIA #integrase #targetedintegration
@biologycentury @MaxPowerNGS @geneeditor @drecwalsh @JamesEKrause
A small targeting domain in Ty1 #integrase is sufficient to direct #retrotransposon integration upstream of tRNA genes - find @pascale_lesage, Joël Acker and colleagues
https://t.co/oF5gYxcy3Q
Grand keynote by Anna Maria Skalka to close the #cshlretro! #retroviruses #hiv #integrase #protease #recombination #reversetranscription #RNAviruses. Read more about the #cshlretro in my blog https://t.co/NGdbqTXLpY
Today's #shoutout to #WomenInSTEM goes to Nicola Cook for her @Sciencemagazine paper on the structural basis of 2nd generation #HIV #integrase inhibitor action & #viral #resistance. https://t.co/4BmkGwSDa4
It’s been spotted! After months of optimisation, a step in the right direction.
Thin-section EM attempt of MVV
@TheCrick @AcademicChatter
#lentivirus #integrase #phdchat #phdlife #microscopy #virus #AcademicTwitter
Os novos esquemas, incluindo inibidores de #integrase, como o #dolutegravir, são potentes e conseguem reduzir a carga rapidamente.
Incrível, né? Parabéns, ânja! E quem tá indetectável por seis meses não transmite o vírus por via sexual!
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