Top Tweets for #LoDoCo
#SaveTheDate for the debate: interesting after the results of #ClearSynergy apparently in contrast with #Colcot and #LoDoCo studies ☀️ #EAS
In this controversy, Prof. Paul Ridker & Prof. Ulrich Laufs brilliantly review the state of the art regarding the challenges of treating inflammation to prevent ischemic cardiovascular complications. The aim of the discussion is to address the question: Is the current knowledge consistent enough to initiate such treatments in addition to the existing therapeutic tools? Learn more: https://t.co/VpxjTetgqY @ProfKausikRay @KatiOorni
#TCT2024 results of #CLEARSynergy : after #COLCOT and #LoDoCo , is there still a place for #Colchicine in post #ACS ? https://t.co/B8o3znL1fJ
💥📜 Read our paper on #Colchicine in #CVD🫀& #atherosclerosis
#COLCOT #LoDoCo & #LoDoCo2 ➡️significant🫀benefit & #FDA approval in #2023 for CVD
More to come #Colchicine from our group..
@HarborUCLA @NCHRooneyHeart @BudoffMd @JairoaldanaMD @JonathonLeipsic @FloridaACC #yesCCT
Individual lifetime benefit from low-dose colchicine in patients with chronic coronary artery disease https://t.co/qCMQUBaoQU #REACH #LODOCO @ArendMosterd @aernoudfiolet @DLBHATTMD @frankLJVisseren @jannickDorrestein
All CAD patients get Aspirin, Statin and #Colchicine . FDA today approved colchicine 0.5 mg (#Lodoco) as the first anti-inflammatory indicated for reducing cardiovascular events among adults who have established CAD or are at risk of developing it. @AGEPHAPharmaUS
Colchicine Poll:
The FDA has approved the anti-inflammatory drug #colchicine 0.5 mg tablets (#Lodoco) as the first specific anti-inflammatory drug demonstrated to reduce the risk for myocardial infarction (MI), stroke, coronary revascularization, and cardiovascular death in adult patients with established atherosclerotic disease or with multiple risk factors for cardiovascular disease.
Will you prescribe colchicine for the indications listed above? Why or why not?
Breaking news today! @US_FDA approved #LODOCO as the first anti-inflammatory drug for #cardiovascular disease. Thrilled to be part of the team supporting this new treatment that addresses the challenge of reducing cardiac inflammation. #clientnews
Colchicine's approval @TCTMD: updated with thoughts from Dr. Paul Ridker & @MichaelJBlaha https://t.co/k1dXpuSvxD
Is Colchicine good for the #heart
The drug inhibits several inflammatory pathways known to be important in #atherosclerosis
#LoDoCo #LowDoseColchicine
#Colchicine 0.5 mg once daily was #SafeAndEffective for preventing #cardiovascular events in patients with #CoronaryArteryDisease
This is my HUGE concern - my brother-in-law was given a #prescription, last week, he took it Mon, Tues, & Wed, TERRIBLE reaction
The #statin & #Colchicine #drugs - they reacted and caused muscle breakdown in the heart #omg 💔💖
@elonmusk @neuralink Is there a cross reference🧰
@Mu7ibullah @abledoc @spkalantri @PriyankaPulla @drkrvcvijay Reassuringly there are 2 trials #LoDoCo & #LoDoCo2 that have established the safety of Low Dose #Colchicine
(Click on hashtags above for more details)
https://t.co/w5IBF0kXxA
@Mu7ibullah @abledoc @spkalantri @PriyankaPulla There is no moral hazard there
Diarrhea has known treatment /medications
The danger is colchicine overdose/poisoning. There is no cure for that.
Which is why its prescribed only in rare conditions
@drkrvcvijay
this @tablerounds connection is no brainer if you heard @thecurbsiders famous @MESternberg talk about it https://t.co/AKHjV8hIGd #lodoco #MedTwitter #medstudenttwitter
@RyanMarino @schneiderleonid @laxswamy
narrow therapeutic index
dose range is very narrow
#LoDoCo & #ColCot trials established acceptable low dose of Colchicine for heart problems @drrobinCCM
Also interactions with other medicines (such as Ivermectin) can create toxicity, I think
https://t.co/Iv9PKmNRCm
@laxswamy I am not sure there is an organ that colchicine won't shut down in an overdose.
@RobertAvramMD @G_MarquisGravel @jbbreau @nthibodeaujarry @jctardif_mhi @brianpotter11 Great study witg a slew of others coming. Absolutely reuqires in-depth read to fully appreciate scope of #LoDoCo but were patients controlled/guided for diet & exercise. 2 well known nonRx methods to quell #inflammation.
#LoDoCo 2 is out confirming the benefits of colchicine in the chronic coronary disease population. Will you start prescribing colchicine in the future in this population? @G_MarquisGravel @hunglymd @jbbreau @nthibodeaujarry @jctardif_mhi @brianpotter11
#LoDoCo 2 summary
LoDoCo-2:
stable CCS patients randomized to
- colchicine 0.5mg once daily
- placebo
#ESCCongress @drdargaray @ALEX_MISCHIE @rafavidalperez
@DrMarthaGulati @MihaiTrofenciuc @pabeda1 @SABOURETCardio @umityasarsinan1 @BiancaItariu @JGrapsa
https://t.co/EGujoUTDvM
Endpoint primario MACE en #LoDoCo trial, colchicina en enfermedad coronaria estable.
Colchicina 0.5 mg diarios redujo los eventos CV, principalmente por la disminución de la incidencia de SCA: 5.3% vs 16% (HR 0.33, IC 95% 0.18-0.59)
@PawanKu71851950 @drpablocorral @ethanjweiss @colcovidtrial @__ice9 @monarchdiaries @drakchaurasia @joex92_ Apparently other than #colcorona trial there seems to have been one more (non-corona) trial on Low Dose Colchicine #LoDoCo
@farid__jalali @drrobinCCM @julienpotet
https://t.co/RkUTA9pSO5
LoDoCo (Low Dose Colchicine) pilot trial showed that the anti-inflammatory drug #colchicine 0.5mg once daily appears safe and effective for secondary prevention of cardiovascular disease [Nidorf SM et al. Am Heart J. 2019] https://t.co/qfUh646Oik Find out about #COLCORONA
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