Top Tweets for #LongnoncodingRNA
#LongNonCodingRNA Liver Fibrosis
LncRNA TILAM
👉Enriched in Activated Hepatic Stellate Cell
👉Located near COL1A1
👉TGFβ-inducible
👉Physically binds to PML➡️maintains PML protein & TGFβ signaling
TILAM LNA or KO➡️⏬Fibrosis in Liver organoid
TILAM KO ➡️⏬ Fibrosis in🐭 + choline-deficient, L-amino acid-defined, high-fat diet or +CCl4
Alan Mullen lab @HEP_Journal 2023
https://t.co/mOVCjet6Sl
The LINC01612-DVL2-WNT regulatory axis promotes human endoderm differentiation – a key modulator of human definitive endoderm differentiation. #longnoncodingRNA #DVL2 #WNT #endoderm https://t.co/wNDj99FYBC
@ISSCR @CellPressNews @GairdnerAwards @SickKidsNews
The emerging roles of long non-coding RNAs in the nervous system. #LongNonCodingRNA #NervousSystem #Genomics #NatureReviewsNeuroscience
https://t.co/BuRjUwSd5K
Long Noncoding RNAs Linked to COVID-19 Severity and Diagnosis
https://t.co/8rvE9xIXX2
#COVID19 #News #SARSCoV2 #Health #Diagnosis #Research #LongNonCodingRNA
Could #NoncodingRNA shape more than moths and butterflies? New research links it to #evolution and #speciation—raising questions about its role in #HumanCognition and beyond. A PNAS Inner Workings: https://t.co/MKU2FKFws1
#microRNA #LongNoncodingRNA #NewVoices @NewVoicesNASEM
#NoncodingRNA plays a crucial role in #butterfly #speciation and #evolution. But what about other #flora and #fauna—or even the #evolution of human #cognition? A PNAS Inner Workings: https://t.co/cdnOEK33TD
#microRNA #LongNoncodingRNA #PepperedMoth #MonkeyFlower
#NoncodingRNA plays a crucial role in #butterfly #speciation—but what about other #flora and #fauna? A PNAS Inner Workings: https://t.co/68FXPkXcl7
#microRNA #LongNoncodingRNA #evolution #PepperedMoth #MonkeyFlower
Just published!🐾
LINC02167 stabilizes KSR1 #mRNA in an m5C-dependent manner to regulate the ERK/MAPK signaling pathway and promotes #colorectalcancer metastasis
Open access🔓
https://t.co/fT6ifPRMXV
#LongnoncodingRNA
#Metastasis
#Transcription
Sequencing CURLY LEAF-associated RNAs in Arabidopsis revealed prevalent intergenic RNAs from the nuclear mitochondrial sequence
https://t.co/Ecow2u8j7c
#Curlyleaf #LongnoncodingRNA #Nuclearcopyofthemitochondrialgenome #PolycombgroupcomplexRNA #immunoprecipitation
#LongNoncodingRNA #SmoothMuscleCell #Seneascence #Atherosclerosis
LncRNA JPX (just proximal to XIST), in complex with #BRD4 NF-κB, acts as a ROS-Cytosolic #mtDNA-STING downstream to transcriptionally activate #SASP genes (IL-1β/-6/-8 MCP1 TNFα) in senescent SMCs
SMC Jpx KO protects against Apoe-/-🐭#Atherosclerosis +⏬lesional SMC senescence SASP
No sex-specific effects
@atvbahajournals 2024
https://t.co/MBedgGRWua
New study!🍉
Regulatory role of lncH19 in RAC1 alternative splicing: implication for RAC1B expression in #colorectalcancer
Look here👇
https://t.co/tAZYoRC1jY
#LongnoncodingRNA
#Alternativesplicing
#RNAbindingproteins
#LongNonCodingRNA #Senescence #Atherosclerosis
JPX, a chromosome-associated regulatory RNA, complexes with BRD4 & p65 (NFκB subunit) to mediates 3D chromatin remodeling &⏫transcriptional activation of senescence secretome genes (CCL2/IL-1β/-6/-8/TNFα) in #SmoothMuscleCell
A prosenescent cascade by HRasV12-#OxidativeStress-mtDNA leak-activated cGAS-STING signaling
SMC JPX KO or JPX gapmeRs i.v. ->⏬🐭atherogenesis & lesional cell senescence SASP
@atvbahajournals 2024
https://t.co/MBedgGRWua
#LongNonCodingRNA #LncRNA transcriptomics Lower-extremity #PeripheralArteryDisease -/+ T2D #Diabetes
Iliac artery n=79
T2D->⏬ACTA2-AS1
#SmoothMuscleCell microdissected from FFPE section
T2D->⏫LINC00910/RUFY1-AS1/MZF1-AS1 ⏬HIF1A-AS3/XIST!/NEAT1/MIR222HG/MIR28B2CHG
More under-annotated LncRNAs to explore!😄
@JaroslavPelisek @SciReports 2024
https://t.co/Wg8n1HZ5SW
Sun et al. delineated role of #lncRNA #PVT1 in enhancing cell proliferation, colony formation, cell migration & invasion & EMT in #colorectalcancer. PVT1 sponges miR-3619-5p & increases TRIM29 levels.
https://t.co/PXtln90l3w
#CancerReports #Wiley #OpenAccess #LongNonCodingRNA
🌟#notablepaper on #ProteinKinaseInhibitor
📚Long Non-Coding RNA #KCNQ1OT1 Regulates Protein Kinase CK2 Via miR-760 in #Senescence and #CalorieRestriction
🔗https://t.co/rlU3KgETKz
👨🔬By Prof. Young-Seuk Bae et al
@MDPIOpenAccess
@MDPIBiologySubj
#inhibitor #longnoncodingRNA
#LongNonCodingRNA #SmoothMuscleCell
LncDACH1⏬SMC proliferation+migration & #Neointima of #ArterioVenousFistula, partially via ⏬HSP90 abundance & sequestrating SRPK1 in the nuclei in an HSP90-dependent manner
LncDACH1 physically binds to SRPK1 (RNA-IP assay)
LncDACH1 is transcriptionally activated by KLF9
A similar pro-intimal role in #Atherosclerosis?
Writing reads a bit confusing; just interpret the data by yourself 😆
@NatureComms 2024
https://t.co/EwDNGIohcP
Latest issue online!📲
LINC00606 promotes #glioblastoma progression through sponge miR-486-3p and interaction with ATP11B
Check it out here👇
https://t.co/N8EVZp6yXt
#GliomaCell
#LongnoncodingRNA
Key point: There is abundant evidence for lncRNA functions other than those stipulated by the competing endogenous RNA (ceRNA) hypothesis in human #epilepsy.
https://t.co/HHIE0ingof
#longnoncodingRNA #neoplasms #neuroinflammatory #ILAE @IlaeWeb @epilepsiajourn @WileyNeuro
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