Top Tweets for #LongNoncodingRNA
Plasma Long Non-coding RNAs for Molecular Diagnosis of Colon Cancer: A Validated Multivariable Model
🌷https://t.co/crFqEGm5Eb
Ann Lab Med. October 7, 2026. Madalin Alexandru Cobzariu
#ColonicNeoplasms #EarlyDetectionOfCancer #LiquidBiopsy #LongNonCodingRNA #StatisticalModels
Directed evolution has worked for proteins and small #RNA what about #LongNoncodingRNA?? Join us to find out!
3 #Postdoc opportunities in #DirectedEvolution, #Epistasis, #FitnessLandscapes, #GenomeEditing, #VariantEffects, #DeepMutationalScanning.
Details: https://t.co/duHUrp4JGf
New Epigenome Technologies Blog! https://t.co/5X3JKbKhtC
"XIST Activity in Males: Towards the Evolution of Dosage Compensation"
#Epigenetics #XIST #PairedTag #EpigenomeTech #lncRNAs #LongNonCodingRNA #Chromatin
#LongNonCodingRNA Liver Fibrosis
LncRNA TILAM
👉Enriched in Activated Hepatic Stellate Cell
👉Located near COL1A1
👉TGFβ-inducible
👉Physically binds to PML➡️maintains PML protein & TGFβ signaling
TILAM LNA or KO➡️⏬Fibrosis in Liver organoid
TILAM KO ➡️⏬ Fibrosis in🐭 + choline-deficient, L-amino acid-defined, high-fat diet or +CCl4
Alan Mullen lab @HEP_Journal 2023
https://t.co/mOVCjet6Sl
The LINC01612-DVL2-WNT regulatory axis promotes human endoderm differentiation – a key modulator of human definitive endoderm differentiation. #longnoncodingRNA #DVL2 #WNT #endoderm https://t.co/wNDj99FYBC
@ISSCR @CellPressNews @GairdnerAwards @SickKidsNews
The emerging roles of long non-coding RNAs in the nervous system. #LongNonCodingRNA #NervousSystem #Genomics #NatureReviewsNeuroscience
https://t.co/BuRjUwSd5K
Long Noncoding RNAs Linked to COVID-19 Severity and Diagnosis
https://t.co/8rvE9xIXX2
#COVID19 #News #SARSCoV2 #Health #Diagnosis #Research #LongNonCodingRNA
Could #NoncodingRNA shape more than moths and butterflies? New research links it to #evolution and #speciation—raising questions about its role in #HumanCognition and beyond. A PNAS Inner Workings: https://t.co/MKU2FKFws1
#microRNA #LongNoncodingRNA #NewVoices @NewVoicesNASEM
#NoncodingRNA plays a crucial role in #butterfly #speciation and #evolution. But what about other #flora and #fauna—or even the #evolution of human #cognition? A PNAS Inner Workings: https://t.co/cdnOEK33TD
#microRNA #LongNoncodingRNA #PepperedMoth #MonkeyFlower
#NoncodingRNA plays a crucial role in #butterfly #speciation—but what about other #flora and #fauna? A PNAS Inner Workings: https://t.co/68FXPkXcl7
#microRNA #LongNoncodingRNA #evolution #PepperedMoth #MonkeyFlower
#LongNoncodingRNA #SmoothMuscleCell #Seneascence #Atherosclerosis
LncRNA JPX (just proximal to XIST), in complex with #BRD4 NF-κB, acts as a ROS-Cytosolic #mtDNA-STING downstream to transcriptionally activate #SASP genes (IL-1β/-6/-8 MCP1 TNFα) in senescent SMCs
SMC Jpx KO protects against Apoe-/-🐭#Atherosclerosis +⏬lesional SMC senescence SASP
No sex-specific effects
@atvbahajournals 2024
https://t.co/MBedgGRWua
#LongNonCodingRNA #Senescence #Atherosclerosis
JPX, a chromosome-associated regulatory RNA, complexes with BRD4 & p65 (NFκB subunit) to mediates 3D chromatin remodeling &⏫transcriptional activation of senescence secretome genes (CCL2/IL-1β/-6/-8/TNFα) in #SmoothMuscleCell
A prosenescent cascade by HRasV12-#OxidativeStress-mtDNA leak-activated cGAS-STING signaling
SMC JPX KO or JPX gapmeRs i.v. ->⏬🐭atherogenesis & lesional cell senescence SASP
@atvbahajournals 2024
https://t.co/MBedgGRWua
#LongNonCodingRNA #LncRNA transcriptomics Lower-extremity #PeripheralArteryDisease -/+ T2D #Diabetes
Iliac artery n=79
T2D->⏬ACTA2-AS1
#SmoothMuscleCell microdissected from FFPE section
T2D->⏫LINC00910/RUFY1-AS1/MZF1-AS1 ⏬HIF1A-AS3/XIST!/NEAT1/MIR222HG/MIR28B2CHG
More under-annotated LncRNAs to explore!😄
@JaroslavPelisek @SciReports 2024
https://t.co/Wg8n1HZ5SW
Sun et al. delineated role of #lncRNA #PVT1 in enhancing cell proliferation, colony formation, cell migration & invasion & EMT in #colorectalcancer. PVT1 sponges miR-3619-5p & increases TRIM29 levels.
https://t.co/PXtln90l3w
#CancerReports #Wiley #OpenAccess #LongNonCodingRNA
#LongNonCodingRNA #SmoothMuscleCell
LncDACH1⏬SMC proliferation+migration & #Neointima of #ArterioVenousFistula, partially via ⏬HSP90 abundance & sequestrating SRPK1 in the nuclei in an HSP90-dependent manner
LncDACH1 physically binds to SRPK1 (RNA-IP assay)
LncDACH1 is transcriptionally activated by KLF9
A similar pro-intimal role in #Atherosclerosis?
Writing reads a bit confusing; just interpret the data by yourself 😆
@NatureComms 2024
https://t.co/EwDNGIohcP
Pleasure to speak at the #APSA 2024 Spring Research Seminar on our lab’s project on linc00152 #longnoncodingRNA in glioblastoma and share some insight into the #TURBOID proximal proteomics approach we’re utilizing to find RNA-protein interactions @A_P_S_A @UABSOM_APSA
#ArticlesInPress: Unlocking the Dark Matter: Noncoding RNAs and RNA Modifications in Cardiac Aging
Jiayi Kang, James Rhee, Chunyan Wang, Yolander Yang, Guoping Li, and Haobo Li
https://t.co/UBcldY7qAy
@lihaobo @MassGeneralNews
#NoncodingRNA #Aging #MicroRNA #LongnoncodingRNA
Enhancer-associated #LongNonCodingRNA #Atherosclerosis
PSMB8-AS1⏫promixal gene transcription of PSMB9 in #EndothelialCell->
Zeb1->
VCAM1/ICAM1->
#VascularInflammation #Atherosclerosis
Serum lipids also regulated by PSMB8-AS1
@CircRes 2023
https://t.co/7EG7oDwnaS
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