Top Tweets for #PolyComb
Epigenetics Update - The dual trxG/PcG protein ULTRAPETALA1 modulates H3K27me3 and directly enhances POLYCOMB REPRESSIVE COMPLEX 2 activity for fine-tuned reproductive transitions https://t.co/w7IxfrHRK0
#Epigenetics #Plants #PolyComb #H3K27me3
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https://t.co/WmSYDGXnzb
RESEARCH PAPER: The conserved N-terminal SANT1-binding domain (SBD) of EZH2 regulates PRC2 activity
By Patriotis et al., and the late David Allis
➡️ https://t.co/jOPDRvxotn
@ael2b @RockefellerUniv @epicypher
#epigenetic #histone #polycomb #lymphoma

🆕 ADVANCE ONLINE 🆕
RESEARCH PAPER: The conserved N-terminal SANT1-binding domain (SBD) of EZH2 regulates PRC2 activity
By Patriotis et al., and the late David Allis
➡️ https://t.co/mkeojloefS
@ael2b @RockefellerUniv @epicypher
#epigenetic #histone #polycomb #lymphoma

Epigenetics Update - Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders https://t.co/wHQVlqu7BH
#Epigenetics #Chromatin #Polycomb #Neurodevelopment
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Gain deeper insights into gene regulation; https://t.co/WmSYDGWPJD

Epigenetics Update - DOT1L provides transcriptional memory through PRC1.1 antagonism https://t.co/hR0W0bobWa
Chen Davidovich/Omer Gilan (Monash University) in Nat Cell Biol
#Epigenetics #DOT1L #Polycomb
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Gain deeper insights into gene regulation; https://t.co/WmSYDGWPJD

Check this new work on BRD4's role in preventing the premature activation of developmental transcription factors via #Polycomb, providing new mechanistic insights into the pathogenesis of neurodevelopmental disorder #CdLS #NDDs, #chromatinopathies https://t.co/H3x3WJ9cUK
Epigenetics Update - Widespread association of Polycomb complex–deposited histone H2A monoubiquitylation with enhancers and neuronal gene regulation https://t.co/ZRrFEIsr2O
#Epigenetics #Polycomb
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Gain deeper insights into gene regulation; https://t.co/WmSYDGWPJD

Epigenetics Update - A chromatin-linked CPL2–PHD2/3 module sustains multiple DNA methylation pathways and Polycomb silencing https://t.co/CDg0IhHaWK
#Epigenetics #Chromatin #DNAm #Polycomb #Plants
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Perfect for cancer, immunology, and aging research; https://t.co/WmSYDGXnzb
RESEARCH PAPER: Dominant-negative effects of Weaver syndrome-associated EZH2 variants
By Deevy et al., Eric Conway and Adrian Bracken @conwayer1 @adrianbracken
➡️ https://t.co/UbX2WIap4q
#weaversyndrome #ezh2 #polycomb #mutation #epigenetics #congenitaldisorder #onthecover

Epigenetics Update - VEL-dependent polymerization maintains the chromatin association of Polycomb proteins for the switch to epigenetic silencing https://t.co/dHaudBYdxd
#Epigenetics #Polycomb #Chromatin
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High-resolution insights without cell sorting; https://t.co/WmSYDGWPJD

Epigenetics Update - SKP1A bound to Polycomb-silenced genes mediates degradation of PRC2 and preconditions their activation https://t.co/Md7qMxvJdx
#Epigenetics #Polycomb #Chromatin
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Gain high-res epigenetic insights at https://t.co/WmSYDGWPJD

Glad to participate in @eLife @eLifeCommunity study led by Luis G. Palma @BigSpinLab @HMar_research showing how non-canonical role for IκBα / NF-κB in #chromatin #histone #polycomb regulation shapes embryonic #stemcell #pluripotency and differentiation.
https://t.co/heWZG0ufKU

Epigenetics Update - The histone H3 lysine 36 demethylase KDM2A/FBXL11 controls Polycomb-mediated gene repression and germ cell development in male mice https://t.co/WWGyZAG7Ze
#Epigenetics #KDM2A #GermCells #Polycomb
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Gain high-resolution insight at https://t.co/WmSYDGWPJD

🆕 New publication from the Tchasovnikarova Lab!
CRAMP1 drives linker histone expression to enable Polycomb repression 🧬
Read the full study in Molecular Cell:
🔗 https://t.co/V0HsLtc1Xd
#Epigenetics #Chromatin #GeneRegulation #Polycomb #GurdonInstitute #SBS_Cambridge
Epigenetics Update - CRAMP1 drives linker histone expression to enable Polycomb repression https://t.co/mzd7VC22vy
Iva A. Tchasovnikarova (University of Cambridge) reproting in Mol Cell
#Epigenetics #Polycomb
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Empower your research at https://t.co/WmSYDGWPJD

Epigenetics Update – “Read–write mechanisms of H2A ubiquitination by Polycomb repressive complex 1” https://t.co/7nSl51z8m3
#Epigenetics #Chromatin #Polycomb
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Gain deeper insights into gene regulation with https://t.co/beJ4EayZs9
Epigenetics Update – “DNA methylation shapes the Polycomb landscape during the exit from naive pluripotency” https://t.co/7VeYZnABTc
#Epigenetics #Polycomb #Pluripotency
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Perfect for cancer, immunology, and aging research; find out more at https://t.co/beJ4EayZs9
👋Our October issue's out!
Cover: Heritable #Amyloids
👉🏻Comment on #EmbryoModels
👉🏼Review: #mitophagy #pink1 #neuroprotection
🔬on: #gastruloids #mechanobiology #Golgi #polycomb #epigenetics #HSF1 #antitumor #Pbodies #cancer & more!
https://t.co/LUPECJz2Uy

💫NEW: Combining degron-based depletion with live-cell transcription #imaging and single-particle tracking, @RobKlose, @AleksSzczurek & co show that #Polycomb keeps promoters in an OFF state by restricting the formation of the pre-initiation complex.
https://t.co/W9m2VQBDN6
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