Top Tweets for #RetFusion
The FDA has granted traditional approval to selpercatinib for RET fusion-positive solid tumors in patients 2 and older after prior treatment. LIBRETTO-001 data showed a 47% response rate over a median 24.5 months.
https://t.co/tbnjuNclUd
#RETFusion #PrecisionOncology
First positive adjuvant pIII study wth selpercatinib in stage IB–IIIA RET-positive NSCLC: LIBRETTO-432. Impressive results!, now in #NEJM. Nicely discussed @christine_lovly TKI duration, MRD, screening, and broader biomarker testing in early-stage #ASCO26 #NSCLC #RETfusion
👉AcceleRET-Lung
👉first line pralsetinib vs chemo +/- IO in RET+ NSCLC with optional crossover
👉Study terminated by sponsor at 90% accrual
👉PFS favors pralsetinib 18.7m vs 9m (HR 0.59) with RR 66% vs 42%, DOR 20.6m vs 9.7m
#LungCancer
#NSCLC
#RETFusion
#ASCO26
Phase III #AcceleRETLung presented at #ASCO26 by @DrSanjayPopat. Upfront pralsetinib in RET+ adds further evidence supporting precision therapy upfront in lung cancer (mPFS 18.7 vs 9.0 months; HR 0.59). Infection-related AEs deserve careful attention. #NSCLC #RETfusion
🗣️Join our Plenary Oral Presentation at #ASCO26. Learn more about a phase 3 study of adjuvant selective RET TKI in stage IB–IIIA RET fusion-positive NSCLC.
May 31, 2:13-2:25 PM CDT, Hall B1, LBA3
Full program info: https://t.co/2qdCGMYpfZ
#RETfusion #NSCLC #LCSM
🎥 Dr. Christina Bestvina shares expert insights on using RET inhibitors to improve outcomes in patients with RET fusions.
🧪 Learn how to optimize care with targeted therapy.
👉 Watch now: https://t.co/DErL36v7ox
#LungCancer #NSCLC #RETfusion #OncologyEducation #CancerCare
Highlights of our 139th Support Group Meeting- Mumbai Chapter
#Lungconnect #LungCancer #RETfusion #Cancerawareness
@DrDarshitshah @trikha_mehak @Sanjeev_33 @oceanblue11oct
#Selpercatinib for RET fusion+ NSCLC: Continuing treatment beyond progression shows promise, especially for oligo & CNS PD. Median post-PD ToT: 9.8 months for oligoPD. Local RT boosts outcomes.
https://t.co/FIkTtfQCW7 #RETfusion
@BenjaminBesseMD
@danieltanmd @JCO_ASCO
The FDA has approved Selpercatinib for treating RET-linked thyroid cancer - @ahmedshahrin
@CR_UK @cancersociety @AmericanCancer @ASCO @OncEd @JCO_ASCO @oncodaily @CancerAdvocacy
https://t.co/79A7f5yTk8
#ThyroidCancer #Cancer #OncoDaily #Oncology #RETFusion
Patients with #RETfusion positive #solidtumours other than #NSCLC do poorly on standard therapy, and could benefit from targeted therapy.
In England these patients can be detected in line with #NTRK testing guidelines thanks to RNA fusion panel testing. #genomics #NHS
DRUG TARGETS: real world data indicate that patients with RET fusions do badly with non-RET inhibitor therapy, highlighting the need to detect this rare but targetable alteration across all epithelial cancer types.
https://t.co/eyvaQNDiRj
Tumor agnostic approvals are becoming more common. 4 new drugs/indications were approved by @US_FDA @FDAOncology for mutation driven malignancies and 3 for skin/soft tissue cancers, here is a summary!
#BRAF #RetFusion #PrecisionMedicine #MedTwitter #OncEd #MedEd @OncoAlert
Updated results of pralsetinib in RET+ NSCLC. 100% (100%!) of treatment-naive patients experienced a disease shrinkage. The CT scan of the first patient we treated in the trial is still on my desk, reminder of the transformational power of good science.
https://t.co/msqRIRpGpd
JULY ISSUE: #RETFusion-Positive #PapillaryThyroidCancers are Associated with a More Aggressive #Phenotype. https://t.co/ucMGJ5hJ2t @McMastersKelly @SocSurgOnc
Amazing effort @VivekSubbiah @JustinGainor @StephenVLiu 👏🏽
This is so incredible for our patients #RETFusion #NoOneMissed
🚨🥁🥁🥁Huge win for RET+ patients.
So honored to present 2 concurrent publications @TheLancetOncol + @TheLancetEndo 👉 Pralsetinib for RET + Lung & Thyroid cancer ARROW trial leading to FDA approval🎯@ASCO #ASCO21 #LCSM #thycsm https://t.co/Qlagq9GiIP https://t.co/XnBhKF0Vt1
Terrific data on intracranial efficacy of selpercatinib in #RETFusion #NSCLC
@ASCO #ASCO21
@VivekSubbiah @alexdrilon
#LCSM @RETpositive @RetRenegades
Fresh off the presses, @MLadanyi and team describe patient-derived models of #RETfusion+ lung cancer & identify how RET drives MYC upregulation:
📰https://t.co/YupHJC0WeI
#OpenAccess #DiseaseModelling @RETpositive @sloan_kettering
How it started.........How it’s going. Thanks to all who got me here. @n8pennell @ClevelandClinic @WrightPattMC #10yrcancerversary #LCSM #retfusion
Genomic testing for all patients with cancer specially rare tumors ( might I add ) 👉🏽with access to high quality clinical trials 🚨 #RETfusion #ASCO20
#asco20 #retfusion #mNSCLC.#selpercatinib preRx mDOR 20.3m,90% ORR Rx naive,93% intra-cranial disease!#pralsetinib Rx naive ORR 88%,12% CR rate!Does v804 gatekeeper=higher CR?2% #nsclc failed by prev TKIs @BlueprintMeds @LillyPad
https://t.co/kGuO0j3bPM
https://t.co/dtaLbjRp4n
Dr. Gainor discussed the significance of identifying RET alterations in patients with NSCLC and the prevalence of this molecular target.
https://t.co/SQlkU7bobj #lungcancer #RETfusion
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