Top Tweets for #SodiumChannel
In a child with a mutation in SCN1A, hippocampus demonstrates abnormal neuronal architecture.
https://t.co/SlvgEdtD0r
#epilepsy #ilae #epilepsiajourn #Ammonshorn #development #Dravetsyndrome #hippocampus #SCN1A #sodiumchannel
Pleased to share our new paper in @PNASNews on #phytocannabinoid targeting of #sodiumChannel Nav1.8 @YaleMed @NeurologyYale:
https://t.co/AYtrn3QKYI
https://t.co/hw4fLJQ1os
One week to go! Get ready to submit your sodium channel manuscripts to this Special Issue at JGP!
With @SwissIonChannel Jeanne Nerbonne, and David Eisner we are editing this collection.
We look forward to your submission by Oct 15! #WWSCC #sodiumchannel #ionchannel #WWNav
📣 #CallForPapers 📣 Deadline approaching! We welcome papers on the role of voltage-gated sodium channels in the broad physiological and pathophysiological context. Submit your work by October 15, 2024 to be highlighted in a special issue 📙 ➡️ https://t.co/ZpnRCHClkJ
@MarlaBroadfoot, @sciam published an article conflating chronic pain patients/prescription opioids w/ “addicts” / the ILLICIT opioids that poison them. Interesting news about new #SodiumChannel med, but lay off us! Opioids work. CPP ≠ SUD https://t.co/ICnmqD5Ezw
@LampertLabRWTH @G_Rossetti_ Extremely interesting finding! By the way, did you know that one can "see" cholesterol molecules in another #SodiumChannel, i.e. #TRPM4 - in yellow below - full ref (Fig. 1): https://t.co/y3SA6pe6qo
Nav1.6 #sodiumchannel @ionchannel can be targeted in
the #heart #drugtherapy for #SUDEP #suddendeath #prevention in #Dravet #Syndrome #SCN1A #seizure #epilepsy #raredisease. @CureEpilepsy @curedravet @DSFeu @DravetUK @dravetsuisse @FundacionDravet @HRSonline @American_Heart ...
Did you ever wonder when Nav1.7 is expressed on the surface of your iPSC-derived sensory neurons? You can find the answer in our latest paper https://t.co/BOnwphjvoh, CRISPR/Cas HA-tagged Nav1.7 and Airyscan for 2 differentiation protocols. @PflugersArchiv #sodiumchannel #pain
A new study from Prof, Deschenes lab. Persistent PKA activation redistributes NaV1.5 to the cell surface of adult rat ventricular myocytes https://t.co/vIcTyYQiDB
@nih_nhlbi @OhioStateDHLRI @OSUWexMed #sodiumchannel @ionchannellib
Trending this week in @physiolrev
New insights into the physiology and pathophysiology of the atypical sodium leak channel NALCN
https://t.co/RVgXDTipQo
#CellExcitability #NALCN #SodiumChannel #Channelopathies
So honored to have @zojaselimi join our lab! Looking forward to advancing our understanding of #sodiumchannel biophysics with @nanocardiology and @SHWeinbergLab. Shout-out to Dr. Jan Kucera and @SwissIonChannel for providing Zoja with solid EP training.@OhioStateDHLRI @OSUWexMed
Also check out our previous work demonstrating the relevance of the microtubule plus end binding proteins EB1/MAPRE1 and EB2/MAPRE2 for #cardiac #sodiumchannel Nav1.5 function #SCN5A and #Brugadasyndrome
https://t.co/2Yw7uxEXDn
and
https://t.co/qPMLPUolYg
@GA_Marchal
Our review published in this week's issue of #CardiovascularResearch
The interplay of microtubule plus end binding proteins and #sodiumchannel interacting proteins mediates NaV1.5 delivery at subcellular domains
summary ⬇️by @GA_Marchal
@CVR_TomaszGuzik
https://t.co/7OhQxzKc3Y
Our review published in this week's issue of #CardiovascularResearch
The interplay of microtubule plus end binding proteins and #sodiumchannel interacting proteins mediates NaV1.5 delivery at subcellular domains
summary ⬇️by @GA_Marchal
@CVR_TomaszGuzik
https://t.co/7OhQxzKc3Y
Finally! Our review which is now out in Cardiovascular Research! It’s about the regulation of the Cardiac Sodium Channel Nav1.5 by Microtubule Plus-End Tracking Proteins. It’s one of the products from my PhD I’m most proud of, so let me give you a short summary: 🧵(1/8)
RESEARCH| Lenaeus et al. define the structural basis for inhibition of the cardiac #SodiumChannel NaV1.5 by the atypical antiarrhythmic drug #Ranolazine, combining #cryoEM, mutagenesis and electrophysiology. @UWPharmacology https://t.co/NyVjvKNN8P
👉https://t.co/4BvdwDycWc
Very happy to announce our next speaker at the WWNavSeminar: Dr. Silvia Priori (Pavia, Italy) will talk about "Inward cardiac sodium current in health and disease." We look forward to seeing you there! #sodiumchannel #ionchannel @SwissIonChannel @IamshanovaO Jannis Körner
Me: Write a haiku about sodium channels
ChatGPT/@OpenAI:
Electric pulses flow,
Sodium gates open wide,
Nerve signals go.
#ENaC #sodiumchannel #sodiumchannels #ScienceTwitter #AcademicTwitter #poetry #haiku #ChatGPT
Next Tuesday, we will have the first WWNav talk of the year 2023 with @LabRubinstein on Dravet Syndrome mouse models for gene therapy development. Come join us for a new round of #sodiumchannel discussions! With @SwissIonChannel @IamshanovaO #WWNav #ionchannels
Happy New Year! We will continue with our WWNav Seminar Series, and start 2023 with a talk on epilepsy and Sodium channels by Dr. Rubinstein on Jan 31st. Visit https://t.co/W3G6Q7RhDB for info and zoom link. @SwissIonChannel @IamshanovaO #WWNav #ionchannels See you there!
Risk of sudden unexpected death in epilepsy (SUDEP) with lamotrigine and other sodium channel modulating antiseizure medications https://t.co/5UQHZKujdn
#epilepsy #ILAE #Lamotrigine #SodiumChannel #AntiSeizureMedications #SUDEP #SuddenDeathinEpilepsy @IlaeWeb @WileyNeuro
Important and insightful work from Jake Miller, @moise_nick and @SHWeinbergLab systematically exploring how polygenic /epigenetic factors modulate #arrhythmia risk in the presence of different #sodiumchannel mutations. #Epeeps
Excited to share our latest work, from Jake Miller and @moise_nick investigating incomplete penetrance in cardiac channelopathies. We want to understand why some people with a genetic mutation in an ion channel present with symptoms and others don’t.@OhioStateDHLRI @OhioStateBME
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