Top Tweets for #Trypanosomes
Thrilled to share our latest work in Nucleic Acids Research! π
We demonstrate that VSG transcripts in trypanosomes play a non-coding role in controlling allelic exclusion, revealing a new layer of RNA regulation.
π https://t.co/Faja7fkXw5
#Trypanosomes #RNA #GeneRegulation
The Dewar lab uses #trypanosomes to investigate molecular mechanisms involved in keeping vital mitochondria working. The extraordinary single tryp mito helps illuminate novel features of mitochondrial quality control pathways while informing drug discovery for #sleepingsickness
African trypanosomes cause disease in humans and animals characterised by waves of high parasite burden accompanied by host fever. Research in the @MickUrbaniak lab funded by #BBSRC is revealing how African #trypanosomes survive host fever, which may lead to new treatments
In our January issue: Do tissue-dwelling #trypanosomes sustain #transmission populations? authored by Stephen Larcombe @jane_munday & @rmc9z highlighting @MonicaMugnier & colleaguesβ @Nature article. #Antigenic #Variation #VSG #Antigen #Differentiation
https://t.co/Rn7TMNkxMn

Our 2025 January issue https://t.co/cbi2BSoKXJ reviews type2 immunity in gut homeostasis & Plasmodium transmission, malaria elimination in Thailand, male & female schistosome interactions, placental malaria & CSP-specific immunity, community ecology of invasive ticks, & more.

Are you interested in #trypanosomes #biomolecularcondensates and/or #geneexpression? We are looking for a highly motivated postdoc to work with with us in the beautiful city of York!
@UniOfYork @YBRI_UoY @BiologyatYork
Please RT!
https://t.co/qaSLw5b1p0

How do #trypanosomes restrict #IFT to only 4 doublet microtubules? 2 hypotheses were proposed (restriction @ the flagellum base or @ the injection) but @Aline_A_Alves reveals it is a third way! It all happens in the proximal portion of the flagellum! (BioRxiv link@ end of thread)

π¨ Postdoc job opportunity - York, UK π¨
- PDRA role available in the lab of Dr Mathieu Cayla at @UniOfYork
- Investigating adaptation of African #trypanosomes to progress through their life cycle in their host
- All details at: https://t.co/qRF3R8hwye
- Apply by 3rd Jan '25
#MeetTheResearcher
Happy to introduce Beth Bakewell-Smith (@bethbkwellsmith) from the Higgins lab this week.
Beth is a DPhil student, investigating how components of human serum provide protection against infection by #trypanosomes.

Read the latest paper from @UoDLifeSciences @WCAIRDundee Anna Trenaman, Michele Tinti, Richard Wall & David Horn in @NatureComms
https://t.co/QSzGULJeIn
@BSParasitology@AmSocParasit @wiparasitology #trypanosomes

Very proud of @cbarnes_5 presenting her PhD project at an International Kinetoplast meeting in Woods Hole, Massachusetts #Trypanosomes #Immunology
Excellent talk by @BLSLancasterUni PhD student Chloe Barnes @cbarnes_5 at KMCB host response session, proud supervisor moment for @LucyHJackson_J @neilneuro @MickUrbaniak

Image shows nanobody-based targeting of Aurora B AUK1 to the inner or outer #kinetochore. From Ballmer, @BungoAkiyoshi et al. showing that Aurora B controls anaphase onset and error-free chromosome segregation in #trypanosomes https://t.co/fmYWCfVlJr
#CellDivision #Microbiology

Aurora B controls anaphase onset and error-free chromosome segregation in #trypanosomes, say Daniel Ballmer, Bungo Akiyoshi @BungoAkiyoshi @BiochemOxford @WTcell and colleagues: https://t.co/DbseRqUZKo
#Microbiology #Genetics #CellDivision #kinetochores

Pam16 & Pam18 are essential for #mitochondrial protein import in eukaryotes, but not in #Trypanosomes. @aschneiderlab show that TbPam16/18 have been repurposed to regulate #replication of #maxicircles within the T. brucei mitochondrial genome #PLOSBiology https://t.co/j65irulVyp

Pam16 & Pam18 are essential for #mitochondrial protein import in eukaryotes, but not in #Trypanosomes. @aschneiderlab show that TbPam16/18 have been repurposed to regulate #replication of #maxicircles within the T. brucei mitochondrial genome #PLOSBiology https://t.co/j65irulnIR

Pam16 & Pam18 are essential for #mitochondrial protein import in eukaryotes, but not in #Trypanosomes. @aschneiderlab show that TbPam16/18 have been repurposed to regulate #replication of #maxicircles within the T. brucei mitochondrial genome #PLOSBiology https://t.co/j65irulVyp


Incredible tribute to phospholipids

Multifunctional Organometallic Compounds Active against Infective Trypanosomes: Ru(II) Ferrocenyl Derivatives with Two Different Bioactive Ligands | Inorganic Chemistry https://t.co/u2ROMs2SQH Gambino & co-workers @InorgChem #ruthenium #ferrocene #trypanosomes #fumarate_reductase

Protein phosphatase PP1 regulation of RNA polymerase II transcription termination and allelic exclusion of VSG genes in #trypanosomes | Rudo Kieft, Yang Zhang, Haidong Yan, Robert J Schmitz, Robert Sabatini
https://t.co/5jFoAIn2lH
Last week I volunteered at the Primary School Parasite Labs. Here I am learning all about #trypanosomes and #leishmania with @jezielbqi and @lvcarruthers π @Hammarton_lab @claireldonald @UofGSii

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