Top Tweets for #sglt1
🔥 Read our Highly Cited Paper
📚 Dual-Targeting #GoldNanoparticles: Simultaneous Decoration with #Ligands for Co-Transporters #SGLT1 and #B0AT1
🔗 https://t.co/OXDoW9dzqs
👨🔬 Giuseppe D’Orazio, Marco Marradi and Barbara La Ferla
🏫 @LaStatale / @UNI_FIRENZE
#glycoderivatives #thiolenecoupling

Among patients with type 2 #diabetes and chronic #kidney disease with additional #cardiovascular risk, #sotagliflozin reduced total MACE and individual ischaemic outcomes of myocardial infarction and #stroke https://t.co/CZ5KleShIl
#SGLT1/2 inhibitor #T2D #CKD #CVD
Online—Effect of #sotagliflozin on major adverse #cardiovascular events: a prespecified secondary analysis of the SCORED randomised trial https://t.co/CZ5KleShIl
#SGLT1/2 inhibitor #T2D #CKD #CVD

New—Effect of #sotagliflozin on major adverse #cardiovascular events: a prespecified secondary analysis of the SCORED randomised trial https://t.co/CZ5KleShIl
#SGLT1/2 inhibitor #T2D #CKD #CVD

@DAICeditor #LexiconPhamaceuticals analysis adds to the body of evidence differentiating #INPEFA as a dual oral inhibitor of #SGLT2 and #SGLT1: https://t.co/snyYztBFtB
Genetic evidence of causal relation between intestinal glucose absorption and early postprandial glucose response: a Mendelian randomization study #SGLT1 #diabetes @Diabetes_ADA https://t.co/DeZKcgLwZ8
#Highlights of Review paper @Kidneydial_MDPI: "The Pathophysiological Basis of Diabetic Kidney Protection by Inhibition of #SGLT2 and #SGLT1" by 𝐘𝐮𝐣𝐢 𝐎𝐞 and 𝐕𝐨𝐥𝐤𝐞𝐫 𝐕𝐚𝐥𝐥𝐨𝐧 @ucsdnephrology
📗Full paper: https://t.co/hljoUJScEN
#DKD #CKD

Dr. Milton Packer: Dual #SGLT1 and #SGLT2 inhibitor #sotagliflozin achieves #FDA approval: landmark or landmine?
Comment by Dr. Milton Packer on the recent #FDA approval of #sotagliflozin (a dual #SGLT1 and SGLT2 inhibitor) with a broad #HeartFailure indication https://t.co/03TROXW9tm
👉https://t.co/4ZzuZzn3CL
Comment by Dr. Milton Packer on the recent #FDA approval of #sotagliflozin (a dual #SGLT1 and SGLT2 inhibitor) with a broad #HeartFailure indication https://t.co/03TROXW9tm
👉https://t.co/4ZzuZzn3CL
The relative increase in #SGLT1 inhibition with #sotagliflozin may provide greater protection from MI and #stroke than the currently available #SGLT2 inhibitors that provide a lesser degree of SGLT1 inhibition
https://t.co/jlbTwa6xAs
@minhaskh @JavedButler1 @djc795 @kaulcsmc @gcfmd @SantosGallegoMD @MasriAhmadMD @mvaduganathan @US_FDA @SJGreene_md @brendonneuen @ShelleyZieroth @ValleAlfonso @ankeetbhatt @SeguraCardio @GoggleDocs No H2H RCT comparison, little incentive for sponsors to do so. Network MA may help?
Trials of Sota in #HF & #CKD were limited to pts w/ #DM2. Empa & Dapa HF & CKD trials included pts without #DM2. PIs of these trials are here & may wish to jump in.
https://t.co/d6N8ZZthFC
🔥Another good news for #Christmas
🎅🏼#Sotagliflozin on the go!
Started the process for #TD2M & #HF approval
💫 1st #SGLT1 & #SGLT2i
https://t.co/OTl6ZT0C2O
@DLBHATTMD @gbiondizoccai @gcfmd @ShelleyZieroth @SABOURETCardio @iamritu @FrancescoPaneni @stefanocarugo @JavedButler1

Latest curated articles👇🏽
📰Thanks for the #NK cell memories (📷)
📰#Structural mechanism of #SGLT1 inhibitors.
🪱#Intestine-specific DAF-2 removal nearly doubles C elegans #lifespan with little #fitness cost
🔗https://t.co/ipXFaj4aIp
🙏🏽Thx @biomednews

Does #SGLT1 inhibition add to the benefits of #SGLT2 inhibition in the prevention and treatment of #HF? 💊
https://t.co/vqzZjw7INJ
#CardioTwitter #CardioTwitter @DLBHATTMD @MarcoMetra @escardio @ESC_Journals

@NephRodby @ASNKidney ~ 90% is oft-quoted but when inhibited, compensatory reabs’n by #SGLT1 kicks in. My point though was that in advanced #non-DKD: 1. little of the #flozin may get to #SGLT2 & 2. unlike in #DM, baseline #SGLT2 activity is not up-regulated, ie normal #Tmax.
Does #SGLT1 inhibition add to the benefits of #SGLT2 inhibition in the #prevention & #treatment of #HF 👉 https://t.co/tRQCKltalS #CardioTwitter @MarcoMetra @DLBHATTMD @SABOURETCardio @rahatheart1 @DrLindaMD @HanCardiomd @kamleshkhunt @ESC_Journals @gbiondizoccai @DrMarthaGulati

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