Happy to share the final version of our paper describing that the widely used Ucp1-CreEvdr transgene unfortunately elicits complex developmental and metabolic phenotypes. This work was mainly driven by @ManasiHalurkar (now a PhD student at Purdue). https://t.co/gDIrJBIxBH
Hi everyone!!! We are excited to re-introduce ourselves as the PhD Program in Development, Stem Cells, & Regenerative Medicine (DSRM) at Cincinnati Children’s! (formerly Molecular and Developmental Biology). Stay tuned for more info on applying to our program🎉🧬!!
We're honored to once again been named to @usnews Best Children’s Hospitals Honor Roll for the 2024-25 rankings. We ranked No. 1 in three specialties, and we placed in the top 10 for all 10 ranked specialties - https://t.co/D0GyBklkv3
Our Human Bone Marrow CITE-Seq Portal (https://t.co/23otvo8YLI) now hosts video and step-by-step walk through tutorials for:
1) Supervised scRNA-Seq annotation (Azimuth)
2) Comparative visualization of RNA & ADTs (ShinyCell).
Please see the on-page and Synapse download links.
My best article @ScienceMagazine. It took ~1 year for me to publish it since its 1st submission. I hope it will positively change the #culture. I hope you will work together with me to make a better world for the next #generations. Please retweet broadly.
https://t.co/EGEC6HC7hg
Thrilled to unveil our latest endeavor: crafting vascularized lung, intestine, and colon organoids with organotypic endothelial and mesenchymal cells via a mesoderm-endoderm co-differentiation approach. Huge thanks to our collaborators @CuSTOMOrganoids@Kottond@YaWenChenMSSM
Can mutant splicing factors programs exist in the absence of mutations? In our new preprint https://t.co/OwDvVZXzsT with @LeeGrimesLab@dstarczynowski@Amitvermamds, we show these programs exist broadly in AML, impact LSC survival and can be reversed. #OncoSplice#PRMT5#IRAK4
Pleased to share our new study @ImmunityCP led by Dr. Emily Eshleman @emeshlem on tuft cell regulation in the intestine. Many thanks to our wonderful collaborators on this project! https://t.co/VB8iQZVD5x
Cincinnati Children's is a cradle of discovery! Our new Research Annual Report showcases a year of innovation fueled by record-high funding. From FLASH #ProtonTherapy to driver safety training for teens with #ADHD, we're improving outcomes together: https://t.co/Tpes4mbaR0 #RAR23
(1) We are excited to finally share “Splicing neoantigen discovery with SNAF reveals shared targets for cancer immunotherapy” at Science Translational Medicine (https://t.co/PMTYM0qkl5). SNAF is an end-to-end workflow for splicing neoantigen & transmembrane epitope prediction...
Very happy to see this four-year collaborative work with Iwafuchi lab is finally published in @MolecularCell
"Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate"
@CincyChildrens
https://t.co/ay36lNz1lG