HFØ

The most focused place on earth.

[HFØ @hf0]

Everyone else is scaling up,
And we're scaling down

Applications close Sunday

[Kerna Labs @KernaLabs]

The mRNA that makes the most protein in a dish can lose its lead in the body. How can AI learn to predict that?

We built an in vivo data factory to measure protein output from hundreds of mRNAs in a single animal. Our co-founder @amitdeshwar explains how.

https://t.co/j5Wwle4seU

[Rissa Cao @rissa_cao]

Introducing @FishAudio Live 3: a full-duplex voice model that listens, says "mm-hmm," and knows when to shut up.

Enterprise? Book a demo for your free custom agent: https://t.co/2kyRhcFMxM

Reply with your use case - we'll build it free for the first 1,000 people.

[Josh Payne @joshpxyne]

The internet is dead. We’ve raised $35M total funding led by Khosla and Hanabi to bring it to life.

@coframe is a growth engine for your website/ads/more which tests, personalizes, & learns 24/7.

It’s working. Dropbox increased conversion by 158%. Replit, 410%. Cash App, 60%.

[Voltropy @Voltropy]

Introducing Vast-10M from Voltropy:

- The first frontier LLM with a ten million token context window

- Beats Anthropic's Fable 5.1 at long-context reasoning

- Early access opens TODAY

[ComfyUI @ComfyUI]

Comfy Router is live

One API for frontier image, video, 3D, and audio models.

Same model string. Same arguments. No new SDK, no new key, no redeploy.

What Comfy Router gives you:

→ Explicit routing. You name the provider, we call that provider. It's down? The request fails there. No silent fallback.

→ Every job returns the provider that ran it. Log it, bill it, debug it.

→ Async. submit() returns a request ID immediately. The queue retries 429s and transient errors until a slot opens. subscribe() submits and polls to completion.

→ Batch-friendly. Queue a few hundred jobs, hold the IDs, pull results as they land. Nothing blocking on a 5-min video render.

→ 24h retention on inputs and outputs, then deleted.

→ Comfy credits. No sub, no Router fee.

Providers at launch: Comfy. Runware, Wavespeed, Fal, Higgsfield. Multi-provider where the model supports it.

Get Your API Key with the link below. ⬇️

[HFØ @hf0]

Congratulations to @alexatallah, @louis_g_v and the entire @openrouter (F23) team!

[evan sc / 柳爱华 @stitesclay]

We were the first firm to invest in @OpenRouter.

When @alexatallah joined @hf0, he had already built a $13B company. He knew what he was doing. He didn't need help.

Alex joined HF0 because we're not an incubator. We don't work with founders who need help.

HF0 is a family...

We live under one roof. We eat around one table. We work tirelessly in pursuit of the singular ideal:

That by removing every distraction, and relentless and fearlessly training one's energy on the most important problem in each moment - massive, seemingly impossible feats of entrepreneurship become tractable.

OpenRouter's journey embodies the fruition of this philosophy.

Just 3 years ago, @alexatallah presented OpenRouter at HF0 demo day. Now, he's here.

[HFØ @hf0]

We opened a new house. Five spots left.

[HFØ @hf0]

Find your zero. Coming soon.

[Fish Audio @FishAudio]

Today we’ve raised $52M Seed and we are announcing the public launch of S2.1 Pro.

>It can clone a voice from 5 seconds of audio
>2x faster than Cartesia & 1/6th the cost of Eleven Labs
>most expressive model with word level control over emotion, intonation, pacing etc

We support frontier AI companies including HeyGen, LiveKit, Retell, Sanas, and OpenArt all run our model in production.

If you're a business and we can't cut your voice AI costs by 50%, we'll give you 1 year of Fish Audio for free.
Book a demo: https://t.co/vHkyZf9JoG

To celebrate our first birthday, we'll give you 1 month of S2.1 Pro for free. Like, retweet, and comment “Fish” to get it.

[Coframe @coframe]

We drove 410% conversion lift on @Replit's enterprise funnel, 2x-ing the number of demo requests. All in a matter of months.

"Coframe makes you feel like you have a team of 100 people. There's nothing on the market like it."

⧉ x ⠕

[Michal Cieplinski @m_cieplinski]

We started building @HiJenny_ai less than 6 months ago to fix American homeownership. Today, on the country’s 250th anniversary, we’re shipping the first-ever AI Home Manager for homeowners and renters.

Jenny itemizes everything in your home via voice, photos, and video so your electronics, art, and valuables are properly documented and insured. She books and manages service calls with plumbers, electricians, HVAC, landscapers, and handymen through an AI voice agent that calls and schedules on your behalf. And when you renovate, Jenny helps you scope the project, pick contractors, and manage the work end-to-end from your phone.

Think ServiceTitan‑class orchestration, but for everyone—homeowners, renters, contractors—without the call center. Already 1,000+ homes are managed with HiJenny. Try the app:

https://t.co/HH4v0se2pL

[BlockRunAI @BlockRunAI]

BlockRun has received an investment from the Base Ecosystem Fund by Coinbase Ventures @cbventures.

This represents a major milestone in our mission to enable AI agents to pay and get paid in @USDC.

We're the No. 1 AI agent payment company by transaction volume.

We're deeply grateful for @Base, @x402, and the @CoinbaseDev .

Our entire tech stack is built on x402 because of its frictionless design—it's what makes agent payments possible at scale.The journey is just beginning. We're building an entirely new economy for AI agents.

[HFØ @hf0]

On the other side of subtraction
Is quiet and rapturous clarity

[HFØ @hf0]

On the other side of subtraction
Is quiet and rapturous clarity

[Seth Blank @AntiFreeze]

We asked Claude to fix one file. It read 47, including the SSH keys.

Spotlight reads your Claude Code + Codex sessions and shows you what actually happened: what to fix, what's burning tokens, what's worth reusing. Free.

[BlockRunAI @BlockRunAI]

Honored to join @HF0 for S26

We're building @FranklinRun_ : an AI agent with its own wallet — it auto-picks the best model for every task and pays per action in USDC.

An AI agent that can pay and get paid. 👇

[HFØ @hf0]

Applications close tomorrow.

[HFØ @hf0]

5 of 10 teams at demo day broke $10M annualized

HF0 is not just for early stage companies

Interviews started yesterday.

[OpenRouter @OpenRouter]

Today we’re announcing our $113M Series B led by @CapitalGVC.

Over the last 6 months, weekly volume on OpenRouter grew from 5T to 25T tokens as AI rapidly shifts from experimentation into production.

We’re excited for what comes next.

[HFØ @hf0]

@goon_altman goon altman is mad.
goon altman is also wrong.
unfortunate.

[HFØ @hf0]

5 of 10 teams at demo day broke $10M annualized

HF0 is not just for early stage companies

Interviews started yesterday.