Heather Gustafson

Scientist. Engineer. Mom. Wife. Lover of macrophages. I run a pediatric cancer lab. Goal = get kids home. Views are my own.

[Heather Gustafson @hhgustafson]

The following video was created for world EoE day to raise awareness and demonstrate the lived experience of EoE: https://t.co/i0uy5SlDSm

[Prof. Hao Wu @WuLabHarvard]

Ever wondered why only inflammasomes that use ASC, but not those that do not use ASC, can mature IL-1β? ASC helps to recruit pro-IL-1β to ASC for caspase-1 processing! See: "Inflammasome adaptor protein ASC is a mechanistic checkpoint in IL-1β maturation" https://t.co/2wWDusQMaJ

[Daniel Barber, PhD @danielleobarber]

So we blocked IFNγ in Mtb infected macaques and….the animals were fine. Turns out mice overestimate the importance of IFNγ in TB because IFNγ drives iNOS in mice but not macaques or humans. This means we don’t actually know how T cells suppress Mtb. https://t.co/vbdpLKjQCa

[Olivier George @brainaddiction]

The new @NIH SciENcv Biosketch pissed me off so much today (lost 4 hours of my life) that I built a quick NIH Biosketch format converter. It lets you format each section while seeing both the preview and the HTML code at the same time.

It restored my sanity, a little.

Enjoy.

[Heather Gustafson @hhgustafson]

These findings suggest that approaches used for HLH may help guide treatment strategies for ICANS, especially when tailored to a patient’s unique immune profile.

Reach out if you are here—we’d love to see you!

[Heather Gustafson @hhgustafson]

We are so excited for #ASH25! If you are here, we’d love to connect and talk about our work on ICANS, IEC-HS, and hyperinflammation following cancer therapy.

Publication #2390 – “Fraternal but not identical twins: HLH and ICANS look a lot alike”

[Heather Gustafson @hhgustafson]

Using scRNAseq from pediatric B-ALL patients treated with CAR-T, we found that HLH and ICANS share biology despite clinical differences. We also show patients can reach similar toxicities through different immune pathways—offering insight into why events are difficult to predict

[nature @Nature]

A huge project has analysed more than 1,000 claims about the immunity of Drosophila fruit flies in scientific papers published over some 50 years

https://t.co/zBju4Kenln

[Heather Gustafson @hhgustafson]

If you cant be at @ASH_hematology today at 2pm to see @seattlechildren and @COGorg own rockstar ⁦@RachelRau3⁩ it’s worth checking out the paper! Out today in the NEJM. Blina for the win! https://t.co/oC8Mki14pb

[Seattle Children's @seattlechildren]

#ASH24 attendees! Don’t miss @RachelRau3 presenting research that’s shaping the standard of care for pediatric #leukemia.

Learn more at today’s Plenary Scientific Session about this study out of @SeattleChildren, @SickKidsNews and @COGorg

[CincyChildren's CBDI @ChildrensCBDI]

Emapalumab extends ‘intervention-free’ survival for children with HLH. @BethanyVerkamp @Mjordanlab

Learn more: https://t.co/He1CIUGyUj

[Petter Brodin @BrodinPetter]

New paper out @Nature - why are males more vulnerable to severe infections (ex acute #COVID), while females suffer more from autoimmunity (SLE, MS etc and also #LongCovid)? sex chromosomes or hormones?

Here we studied adaptation of human immune systems to gender-affirming testosterone treatment in trans-men assigned female sex at birth: https://t.co/HzCQI6GUwn

[Heather Gustafson @hhgustafson]

Congratulations Aya and Blair! ⁦@UW_M3D⁩ is so lucky to have you. I am so proud to have been a small part of your journey. Best of luck as you move into the future. Medicine is a bit brighter today! :)

[Kanneganti Lab @KannegantiLab]

We enjoyed reviewing NLRs @ImmunityCP. Check out NLR evolution, networks, and diverse roles in #cell death, #immunity, and #disease. Congrats to first author @BalaTejashiva, along with @RebeccaTweedell, Prasanth Kumar, & @ThiruKanneganti @StJudeResearch!
https://t.co/KpX1uCOm2O

[Heather Gustafson @hhgustafson]

Utah you are always so beautiful. I miss spending time in the mountains! Thank you @UtahBME and @H_Ghandehari for the invite. I am super excited to see the department and to share our work on HLH tomorrow.

[The American Association of Immunologists (AAI) @ImmunologyAAI]

Samantha Yeligar from Georgia and several other AAI Public Policy Fellows had the opportunity to meet with @SenatorWarnock during #PPFPHillDay. Thank you, Senator Warnock, for taking the time to talk with us and supporting biomedical research!

[Derek Theisen @stave000]

Had an excellent meeting with staff from @SenEricSchmitt's office about the importance of robust federal funding for biomedical research. @ImmunologyAAI and the immunology research community appreciate your support. #PPFPHillDay

[Molecular Pharmaceutics - University of Utah @PHCEUutah]

Applications for our Summer 2024 Undergrad Internship are due March 15. We are excited to welcome another fantastic group of students in 2024!
https://t.co/KEO0deUhQG

[National Organization for Rare Disorders (NORD) @RareDiseases]

The rare pediatric #PRV program offers incentives for companies to develop therapies for children living with #RareDiseases, less than 5% of which have treatments today.

NORD urges Congress to reauthorize the PRV program before it sunsets in September! #RareDiseaseWeek