hilal

itu MSc • molecular biology and genetics 🧚🏻‍♀️🧬🌷

[Science Magazine @ScienceMagazine]

Proteins, with their varied structure and chemistry, are the prime actors of biology and have long been targets for in vitro and in silico engineering. Generative protein models and other artificial intelligence tools are now being integrated into experimental workflows.

In a new #ScienceReview, researchers take a look at advances in AI methods and discuss how statistical principles are being used to transform protein engineering through conditional generative modeling.

Learn more: https://t.co/1LxXJtMHVD

[Science Magazine @ScienceMagazine]

For decades, biology textbooks have enshrined a simple rule: DNA is made by copying a template. After one enzyme unzips a DNA double helix into separate strands, another called a polymerase builds a complementary sequence, base by base, for each strand. Presto: two copies of the original DNA.

But new research into how bacteria defend themselves from viruses now shows this synthesis rule isn’t absolute.

Now, a team describes a bacterial enzyme that synthesizes DNA without a nucleic acid template, using its own structure as a guide.

Learn more on #DNADay: https://t.co/ksN5lBxRw3

[Mohammed Ali Alshehri د.محمد الشهري🇸🇦 @maab515]

Top databases every bioinformatician should know, whether you’re working in genomics, proteomics, or systems biology, essential resources

[gen0m1cs @gen0m1cs]

Happy DNA Day.

[Jake Wintermute 🧬/acc @SynBio1]

Of @plasmidsaurus he is a fans
He pipette too big for he tiny hands

[World of Science @Science_TechTV]

The complexity of the human brain.

[Oz @oznova_]

This is what amino acids look like if you let the side chains flop around on the page

[Science Magazine @ScienceMagazine]

Can internet use become addictive?

A 2022 #SciencePerspective discusses the addictive potential of the internet and how it can be best conceptualized and evaluated. Learn more: https://t.co/Fv3BzuPSR4 #ScienceMagArchives

[Nick Desnoyer @NickDesnoyer]

"Imagination is everything. It is the preview of life's coming attractions" -Albert Einstein

[Jeffrey Millman @JeffreyRMillman]

Our qPCR data is now protected by sharks!

[Sebastian S. Cocioba🪄🌷 @ATinyGreenCell]

biblically accurate mRNA be like

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

[Nature Reviews Drug Discovery @NatRevDrugDisc]

Today's Nobel Prize for Physiology or Medicine relates to research on regulatory T cells https://t.co/rUp92Opbx3

For readers interested in harnessing the biology of regulatory T cells to treat disease, here's a comprehensive review https://t.co/4CVfcN5Y2r
https://t.co/z83V1d8cOQ

[Simon Maechling @simonmaechling]

Huntington’s disease is brutal.

A single DNA error → toxic protein → dead brain cells.
No cure. Always fatal. Always inherited.

But now? Science has flipped the script.
How the new gene therapy works:

1️⃣ Huntington’s mutation makes a toxic protein that kills neurons.

2️⃣ Doctors infuse gene therapy directly into the brain through a catheter.

3️⃣ Neurons absorb the genetic code - and turn into mini drug factories.

4️⃣ The therapy blocks the faulty messenger RNA → less toxic protein.

The result?

A 75% slowdown in disease progression.
Patients still walking when they should be in wheelchairs.

One man back at work after being medically retired.

This is not science fiction.
It’s genetic medicine, delivered in real time.

Advanced science…
To families living with Huntington’s, it feels like magic.

[nature @Nature]

Scientists have created a tool that manufactures working proteins directly on the surfaces of cells

https://t.co/NPRsz7Ew9B

[Kathy Y. Wei, Ph.D. @KathyYWei1]

Proteins are the new yarnballs?

[hilal @hilalbadoglu]

49th FEBS congress in Istanbul ✨

[allen institute @AllenInstitute]

The fireworks in your mind. 🧠✨ This sparkling video shows the neurotransmitter glutamate being released into synapses, made possible by an indicator developed by @abhi_aggarwal1, @PodgorskiLab, and team.

#HappyNewYear #NYE

[Danielle Beckman @DaniBeckman]

Amyloid-beta: Villain or Hero?
Aβ can act as an antimicrobial peptide by trapping pathogens like bacteria, fungi & viruses in extracellular fibrillar proteins. But chronically, it can lead to neuroinflammation & degeneration.
Image: Human #Alzheimer brain
#FluorescenceFriday

[Science News @SciencNews]

Inside Out🥂