1/ Why can you encounter an allergen repeatedly before becoming allergic to it? In our new @ImmunityCP paper, led by the wonderful @XuepingZhu, we asked whether the sensory neurons that first detect allergens might carry a record of earlier exposures. 🧵
https://t.co/9lTuq2vf87
This was so much fun to write, thank you @SwirskiLab and @FGinhoux !!
A summary of the many surprising jobs that immune cells do after hours (and it is more than just cleaning up)
Immune system influence on physiology | Science https://t.co/YgL1nn9l9K
Tomorrow, I’ll be standing for science with my lab in NYC. Come learn what we do, why we need support to continue, and how this impacts everyone—because no one is immune to disease. Hope to see many New Yorkers, not just scientists, standing with us. https://t.co/lI0DLVq7dD
I'm elated to share that my postdoc work is now online @Nature!
https://t.co/3OoV6L5hDq
If you are interested in neuroimmunology (gd T cells, IL-3, sensory neurons) or allergy (allergic itch and initiation of the allergic immune response), this paper is for you! (1/16)
Looking forward to sharing some of our research in the last years on sensing, immunotherapy and connection of myeloid cell metabolism and function!!! Thanks @globalimmuno for the invitation!
The Spatial Human #Macrophage Map is finally online in @CD_AACR! We show how phenotypically distinct macrophage populations occupy spatially segregated tissue #niches, with #IL4I1 and #SPP1 TAMs predicting opposite outcomes in colon cancer!
Thrilled to have our work mapping tissue remodeling in intestinal inflammation online! An amazing collaboration between @SivanathanKisha and Paolo and Jeff in the @MoffittLab probing the diversity and origin of #inflammation associated #fibroblasts. https://t.co/9QbwgmEvp9
Extremely happy to share our latest work from the
@Transactivator lab! We show that the immunosuppressive PD-1/PD-L1 pathway is active in neonatal mouse hearts and required for regeneration 🫀Huge thanks to co-author @MiaoCui_713 and all other authors! https://t.co/oVeVBnRgrv
Breakthrough discovery by my friend Angelo Lombardo and team @nature!! Long-lasting gene silencing IN VIVO with "hit and run" epigenetic editing.
So many applications and therapeutic implications 🤯
https://t.co/jJtn0nE7V4
Touch sensation requires the mechanically gated ion channel ELKIN1 | Science https://t.co/wwfuaIGVsA
Super proud to present our latest work led by Sam @fluorescence_SC , we identified ELKIN1 as necessary for normal touch sensation in mice and in human sensory neurons too!