Check out our review in @UrologicClinics on adjuvant therapy for muscle invasive bladder cancer! IMvigor011 has defined a new disease state with MRD, and MODERN will provide key insights to further guide our management
https://t.co/ee8GHrXTRX
• The entire concept of Confidence Interval captured in a simple doctor–patient conversation
• Wide CI ≠ weak drug
• Often reflects fewer events.
Stats, explained the OPD way 👇
#Oncology#MedEd#ClinicalTrials#StatsSimplified
🌟🔵 TALAPRO-2: Who Should We Test? Ideal Candidates for Treatment
👨⚕️ Presented by Dr. David Lorente
🕐 #GUARDSymposium2025@OncoAlert
🔵 Test all metastatic prostate cancer patients ➡️ offers prognostic, predictive, and familial risk value
🔵 Test as early as possible (currently standard in mCRPC; implications for mHSPC expected soon)
🔵 HRR gene alterations identify candidates for PARP inhibitors (alone or combined with NHAs)
🔵 Talazoparib + Enzalutamide → the only PARPi + NHA combo showing OS benefit in a phase III trial
🔵 Best results in BRCA-mutated cases, but benefit also observed in other alterations
🔵 Key considerations to find ideal candidates:
🔹 What is the HRR alteration and its type?
🔹 What was the prior therapy (ARPi/APA/ENZA/DARO)?
🔹 What is the patient's general status and disease burden?
🔹 What are the treatment goals?
@tompowles1@ProfSyedHussain@MattGalsky@AndreaNecchi@DrFelixGuerrero@malvarezmaestro@urbano_anido@JaviMolinaC@Dav_Lorente@vital_hevia@AnaPlatabello1@dperfen@DrIacovelli@PBarataMD@Uro_Dominguez@Uro_Oncologist@RodriguezAntona@cdanicas@drenriquegrande@Ecastromarcos
📌 #ProstateCancer #mHSPC #HRR #PARPi #BRCA #TALAPRO2 #OncoTwitter
Nuevo León tierra del mejor acero, del mejor concreto, de ingenieros de lo mejor del mundo arruinados por la maldita corrupción en los gobiernos que no pueden hacer un puente vehicular bien hecho porque “así no deja”
A beautifully crafted review “Towards targeting the breast cancer immune microenvironment” in @NatureRevCancer by @LoiSher et al not only closes a gap in our up to date understanding of immune microenvironment, but is graphically 🔝
Bravo. Required read.
https://t.co/vu58ecGQ85
Es inaudito y frustrante por decir lo menos, el desenlace en el caso de María Elena Ríos @_ElenaRios.
Una vez más triunfó la injusticia y la impunidad en un caso extremo de violencia contra una mujer.
Qué pésimo mensaje para todas las demás...