Many (belated) thanks to the organizers and everyone at @VoM_2024 for rekindling my stoke for phages and providing an excuse to finally visit Australia and dive the GBR
Congrats @kr_gerbino on your first 1st-authored paper. Krista found that our molecular model for how lambda evolves to use new receptors applies to phi21 too! 🧵
https://t.co/zejoKfAxCW
Please share! Here's our latest preprint on the university-wide mentorship program @bummp_ucsd, highlighting its profound impact on biology students from all backgrounds. In 4 years, this pioneering initiative has served over 1,350 mentees!!!
https://t.co/lC040QeITh
New @biorxivpreprint on optimizing experiments to infer multiphasic decay of infectious viruses, led by Jeremy Seurat & @justinrmeyer team, we leverage synthetic sims to design, implement and identify a hidden majority of rapidly decaying phage
https://t.co/v1NlqVTnyV
Niche theory does not explain how species evolve to exploit unique niches. Using experimental and computational approaches, Doud et al. show that resource competition can deform fitness landscapes, promoting ecological speciation.
@justinrmeyer
https://t.co/r4PSFXRzmH
Amazing work @ScienceMagazine from @ucsdbiosciences Josh Borin @jm_borin@justinrmeyer lab
In just 21 days of laboratory coevolution, Escherichia coli and bacteriophage Φ21 coevolve and diversify to form elaborate cross-infection networks.
https://t.co/WbVhxu1REk
Our newest paper was published today, a capstone to our work on gain-of-function evolution, phage-bacterial interaction network formation, and microbial diversification.
Today in @ScienceMagazine: Rather than a slow, gradual process as Darwin envisioned, biologists can now see how evolutionary changes unfold on much more accelerated timescales. @justinrmeyer@jm_borin@UMDscience https://t.co/Yf52JQuoas
.@EnustunEray (@ucsdbiosciences) and colleagues have used proximity labelling and localization mapping to systematically map out the protein interaction network of the ‘#phage nucleus’ made by jumbo phages.
https://t.co/WD9SowaHYT
Congrats, Infectious Disease Fellow Mike Doud on an incredible paper quantifying the fitness landscape underlying bacteriophage lambda speciation. Also congrats to @anigupta12 and several talented coauthors who made important contributions. 🧵https://t.co/B8m8X7OToN
3rd chapter from my PhD is published! We used mouse models to test the effect of fecal VIROME transplants on the microbiome and host physiology.
💉🐁💩🦠
https://t.co/BSwFedBY4E
Some jumbo #phages have evolved a protein shell that encloses their replicating genome. @EnustunEray etal have used proximity labeling to identify a ‘phage nucleus protein interaction network’, including 6 uncharacterized nuclear shell-associated proteins
https://t.co/LUwIwfzgV4
📢New review alert 📢
Developing Phage Therapy That Overcomes the Evolution of Bacterial Resistance (proof posted online)
My first piece of publication from @PaulTurnerLab@QbioYale@YalePhage 🎉🥳
https://t.co/UsdKpQqWCA