I am so happy to share my first author paper published at Genome Research last week about the roles of a transcription factor encoded by EBV in autoimmune diseases
I would like to thank all of the co-authors especially to Dr. Matt Weirauch my PhD advisor, and Dr. Leah Kottyan!
I am excited to share this new study on how EBNA2 rewires chromatin at autoimmune risk loci from our group with co-corresponding author Matt Weirauch https://t.co/L0SRalUfcb @CincyKidsGenomX
@CincyMedicine@CincyChildrens 1/7
Exited to share our review "Human Virus Transcriptional Regulators" done in collaboration with the Weirauch and Marazzi labs and led by @XingLiu45796855 and @joyer04 https://t.co/ASEVpqv23d
Looking forward to continue/initiate our collaborations with the Weirauch, Marazzi, @Kottyan_Lab , @EmilyMiraldi , @TrevorSiggers , and Emili labs to functionally characterize these vTRs.
We provide a catalog of 419 viral transcriptional regulators (vTRs) from human DNA and RNA viruses, describe their functions, roles in regulating viral and host gene expression, and impact in human disease.
Great review by Ted Hong @joyer04 and Xing Liu from Weirauch lab and Fuxman Bass lab @fuxmanlab! Viral proteins can act as host transcriptional regulators. They attempted to annotate these factors and discuss their importance in human disease. It will be a valuable resource.
Epstein-Barr virus nuclear antigen 2 (EBNA2) extensively rewires the human chromatin landscape at autoimmune risk loci https://t.co/JADSPliSE8 #bioRxiv
Epstein-Barr virus nuclear antigen 2 (EBNA2) extensively rewires the human chromatin landscape at autoimmune risk loci https://t.co/XdjhNhlTLh #biorxiv_genomic
@Kottyan_Lab highlight a critical role for EBNA2 in rewiring human gene regulatory programs through rearrangement of the chromatin landscape and nominates components of genetic mechanisms that influence the risk of multiple autoimmune diseases. https://t.co/Ho8e2ZfTB6