Preetish Murthy

Assistant Prof at University of Illinois Chicago.

[Maor Sauler @maorsauler]

Excited to share this work, now out in @NatureGenet . There is no cure for #COPD. To tackle this challenge, we performed nuclear sequencing, spatial transcriptomic, and proteomic analysis of lung tissue from 141 subjects to better understand this disease. https://t.co/XMPSDXzEkt

[Jason Spence @TheSpenceLab]

Excited to share our latest preprint:

A spatially-resolved blueprint of the developing human lung reveals a WNT-driven niche for basal stem cells.
https://t.co/ZrQGvftbW3

Led by a talented team: @PeggyPHsu, Tristan Frum and Ansley Conchola - and with many other contributors!

[Nick Banovich @NeBanovich]

I'm incredibly excited to share our most recent work: "Image-based spatial transcriptomics identifies molecular niche dysregulation associated with distal lung remodeling in pulmonary fibrosis"

https://t.co/GzxJFXuvDA

[jon kropski @JKropski]

Excited to share new work from our group led by terrific @VUMC_MedPSTP @VUMCLung fellow Scott McCall

Hypoxia-inducible factor-2 (HIF2) regulates alveolar regeneration after repetitive injury https://t.co/zb411mKtGS

[Lisa Sikkema @SikkemaLisa]

Today our Human Lung Cell Atlas (HLCA) paper came out in Nature Medicine https://t.co/PAb5zP53p5! The HLCA includes 2.4M cells from 486 individuals and 49 datasets. Check out this tweetorial to learn more about how we built it, and how you can use it (1/21)

[Jason Spence @TheSpenceLab]

A new manuscript from the lab led by MSTP student, Ansley Conchola, with @tristanfrum @PeggyPHsu and others...

Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung

https://t.co/d2q7f8T8IJ

[Nick Banovich @NeBanovich]

Incredibly excited to share out latest work using single cell RNA sequencing to identify eQTLs across 38 cell types in primary human lung tissue. https://t.co/6SMFGZtDvZ 1/n

[Rong Fan @RongFan8]

Spatial epigenome–transcriptome co-sequencing🤩🤩🤩Beyond excited to see it out today @Nature! Enjoyable collaboration between my lab @YaleBME @YaleSEAS @YaleMed and @GoCasteloBranco of @karolinskainst. The most informative tool for spatial multi-omics!!
https://t.co/hRTtfGVbno

[Darrell Kotton @Kottond]

Hot off the @biorxivpreprint press: check out our latest work, making the world's flattest cells: "Generation of human alveolar epithelial type I cells from pluripotent stem cells" @CReM_Boston @BUPulmonary https://t.co/IadhINhinH

[Bravo-Cordero Lab @BravoCorderoLab]

Big day in the lab! Always wanted to study how dormant cancer cells interact with #brain cells. Thanks to the support of @TheMarkFdn we'll do it! We are recruiting! Neuroscientist, computational scientist interested in vivo #imaging, #spatialtranscriptomic, #dormancy DM/email me!

[Herbert B Schiller @SchillerLab]

[1/20] Modeling disease directly in human tissue slice cultures transforms mechanistic studies as well as drug development and translation. A thread on our new work @biorxivpreprint.

https://t.co/7P2FfVRgLo

Two amazing first authors: @niklasjlang @schniering_j
@HelmholtzMunich

[Marko Nikolić @drmarkonikolic]

Delighted to share our pre-print on "Early human lung immune cell development and its role in epithelial cell fate" https://t.co/IDuavYvWWa in collaboration with Sarah Teichmann & Kerstin Meyer @teichlab @sangerinstitute. Thanks especially to the amazing co-first authors...(1/2)

[Rawlins Lab @LabRawlins]

Brilliant to see this come out. Especially congratulations to the co first authors @KyungtaeL @PengHeCam @sundakao

[Arvind Konkimalla MD/PhD @arvikonk]

Excited to share my first 1st-author pub from @Tatalab_Duke!
A quick 🧵:
Have you ever seen an epithelial cell with more than one apical domain? Here, we present evidence for multi-apical polarity of alveolar stem cells (AT2s) @iScience_CP
https://t.co/wc2QOtZOz1 (1/6)

[Preetish Murthy @klpreetish]

@regenknol @UICPharmacology @UICEngineering Congratulations!!

[Supriya Vartak @VartakSupriya]

Ever wonder how Transcription Factors work as a team?
Thrilled to share our latest work on TF cooperativity now online @MolecularCell
“Stripe” TFs provide accessibility to regulatory DNA in mammalian genomes
https://t.co/xjoY5CBblc
What are stripe TFs, you ask?
🧵👇

1/13

[Jason Spence @TheSpenceLab]

New preprint by @UMichCMB #UMichMSTP student Ansley Conchola, with lab mates @tristanfrum @PeggyPHsu and others. In collab with @klpreetish @Tatalab_Duke.

Distinct airway progenitor cells drive epithelial heterogeneity in the developing human lung.

https://t.co/aXzrdAN4lD

[Sweet-Cordero Lab @ UCSF @SweetCorderoLab]

🚨📣💥 the @SweetCorderoLab is hiring a #postdoc interested in studying sarcoma metastasis with single cell omics and lineage tracing in unique patient-derived models and GEMs. Highly collaborative environment @ UCSF… join us!

[James Briscoe @briscoejames]

New from the lab: @robertblassberg & co on how the levels of SOX2 influence where WNT signaling effectors bind to chromatin

This determines the WNT response & explains how one signal elicits different responses in different cell types #OA

https://t.co/bNyoXtN3PR

[Young Embryologist Network @YEN_community]

During our second session, Ying Zhang, @EManiou @_Bethan_Clark and @klpreetish will take the stage to talk about brain sparing, lung progenitors, pigmentation patterns and biomechanics 🧠🫁🐠👩‍🔧