This UMAP plot was generated from data simulated without inherent clusters, meaning the observed clusters are artifacts.
It highlights how default Seurat clustering and UMAP settings can sometimes produce misleading patterns in data visualization.
🧬 We’re excited to introduce D&D-seq, a single-cell technology that maps DNA:Protein interactions through molecular footprinting.. Check it out here: https://t.co/mfsDO3kKa0 #Genomics#Epigenetics
Fantastic thread here from @Jess_Osterhout on building a brand as a scientist! If helpful, I wrote some of my thoughts on this important topic a few years back. 😊
https://t.co/jp1hfQKE2M
Out work about "Single Cortical Neurons as Deep Artificial Neural Networks" was finally published in Neuron
With @mikilon and @Segev_Lab@NeuroCellPress paper: https://t.co/XOrRxVVEjO
code: https://t.co/IGH8DmCucr
data: https://t.co/QswJsD5zfV
All new results in thread below
Do you do RNA seq quantification with long reads? Well, the COMBINE-lab has something cooking that you might be interested in trying out!
#RNAseq#quantification#transcriptomics
https://t.co/Eg8ZoOT6RL
Our latest out today in @Nature. We profiled 12 million single cells from mouse embryos spanning gastrulation to birth, defined cell type tree from zygote to birth, and unexpectedly found crazy fast changes within first hour of extrauterine life. OA PDF: https://t.co/7PsCcqaQS8
Ever analyze a scRNAseq dataset and wonder if a specific cell state has been seen before? And if so, where in the human body? Under what conditions? Well, now you can use our lightning fast SCimilarity search and foundational model for that! ⚡️🔎🧬 https://t.co/t8L1xFOffd (1/11)
1/6 A little thread to celebrate this milestone! Our SIMBA manuscript has finally seen the light of day, after a journey of more than 2 years. It's been an intense ride, but we're thrilled with the result.
Want to use deep learning for image analysis but lack the coding skills? We introduce DELiVR, a game-changer in brain-wide cell analysis. No coding required, our Fiji Plug-in does the magic. Hats off to @Dorie00, @Rami96614090, @moritz_negwer! 🧵👇🏼 1/n https://t.co/pl7Hwvo2sp
It was a tour de force just generating a draft human pan-genome @HumanPangenome, but some suspected and some utterly bizarre things about the human genome have been revealed using these 47 different human reference quality genomes.
My favorite T2T/Pangenome discovery so far: a multi-megabase inverted segmental duplication on the short arm of chr14 that explains the mechanism of Robertsonian translocations. Great writeup by @ScienceStowers "Answering a 50-year-old mystery" https://t.co/u90TGUwnYt
We’re excited to announce 20 new Data Insights grantees addressing challenges in #SingleCell biology by:
🔹Integrating data sets to understand cell functions that regulate health + disease
🔹Applying #ML methods to the analysis of complex data sets
https://t.co/kXZMQ5jB2T