Lisa

Post-doctoral researcher @SwantonLab at the Francis Crick Institute, UK

[Waggoner Lab @LabWaggoner]

Pan-cancer spatial atlas of tertiary lymphoid structures
https://t.co/VCjsaqtX4T
@ScienceMagazine @IamLinghua
@UTMDAnderson @kyungserkcho

[David Sancho @SanchoLab]

How does oxygen sensing shape alveolar #macrophage (AM) identity?
In our new @CellReports HIF-1α and HIF-2α play distinct, non-redundant roles in AM maturation & function
A #metabolic split that defines macrophage biology in the lung.
OPEN: https://t.co/1pxnHMUWgZ
@CNIC_CARDIO

[Waggoner Lab @LabWaggoner]

In vivo single-cell ribosome profiling reveals cell-type-specific translational programs during aging
https://t.co/XZ3LTO9FfX

[Marcus Goncalves @MarcusDGon]

Tumor-immune-neural circuit disrupts energy homeostasis in cancer cachexia https://t.co/wcUi6ZF6Jr

[Adrian Liston @LabListon]

I'm officially an expert in failing! I was asked to give the opening keynote today for a @CRUKCamCentre conference, speaking on the topic "Failing in Science"

[Roychoudhuri Lab @RoychoudhuriLab]

Incredible new paper from Max Krummel's group showing that macrophages sample cellular content from living cells to present to T cells! https://t.co/fcZBiyw41D

[nature @Nature]

Nature research paper: Early fibrotic niches establish tumour-permissive microenvironments

https://t.co/59lRB5bioq

[Waggoner Lab @LabWaggoner]

CAR-neutrophils produced in vivo to treat glioma @natBME @PurdueResearch @penn_state
https://t.co/uFwVeB8n1a

[ISCaM -International Society for Cancer Metabolism @ISCaM_Society]

Do not miss the opportunity to join a great community and catch up on the latest developments in Cancer Metabolism. Terrific lineup + many many slots for selected speakers. Sponsored Travel Grants available. REGISTRATIONS ARE OPEN.

[Lung Cancer Europe @LungCancerEu]

New research in Nature suggests cancer cells can learn to resist therapy, not by mutating, but by reprogramming themselves.

In #lungcancer, resistance to targeted treatments is a significant challenge. Understanding how this happens is an important step in the search for better treatment

🔗 https://t.co/RvSA6FljUj #LCSM

[Adrian Liston @LabListon]

We have an exciting new story out at @ScienceMagazine's Science Immunology! It is about using #AAV cytokine delivery to change the lung environment. We can boost #lung #Tregs or delivery anti-inflammatory #cytokines, preventing fatal respiratory collapse

https://t.co/Duj2MXx6VX

[Kivanc Birsoy @KivancBirsoy]

Our new work by @shanshanliu1218 and @gadmark addresses a fundamental question: how does ER maintain its unique oxidizing environment, while rest of the cell is reducing? Here, we identify SLC33A1 as the major ER GSSG exporter in mammalian cells. https://t.co/cmbOm2u3t7

[Eric Topol @EricTopol]

Towards Spatial Medicine for individualized cancer immunotherapy @SciImmunology
"The convergence of spatial biology platforms, single-cell immune profiling, and machine learning is positioning the community to decode how T cell immunity is spatially organized in human tissues and to
exploit that organization therapeutically"
https://t.co/tYaEyusANy
https://t.co/AHvBzGQE2e

[Roberto Vendramin @RobertVendramin]

🚨Paper alert🚨 Very excited to share our manuscript, published today in @ImmunityCP, where we describe how ‘Nonsense-mediated mRNA decay inhibition reshapes the cancer immunopeptidome’. (1/16) https://t.co/S58jZLKZ7G

[Waggoner Lab @LabWaggoner]

Exposed phosphatidylserine is an inhibitory molecule in T cell exhaustion @Nature @EmoryUniversity @rafiahmed_lab
https://t.co/fUvGgSJhaq

[Science Immunology @SciImmunology]

#Macrophages can restrict immune infiltration of #tumors by inhibiting the formation of collagen III-rich networks that permit T cell and neutrophil entry. @heleneDmoreau @LennonLab

Learn more in Science #Immunology: https://t.co/gHEPYlM3P7

[Malcolm Sim @mjwsim]

The Sim lab has been hard at work and we’re proud to present our first paper.

We developed new methods to study peptide:KIR interactions.

Congratulations to star postdoc Tanusya Murali who led the project.

https://t.co/hN0fbGOSRx

[Waggoner Lab @LabWaggoner]

@biorxivpreprint CRY-NLRP3 complexes are a circadian checkpoint that modulates inflammasome activity and drug response, revealing time of day as a critical dimension of NLRP3-driven inflammation
https://t.co/qvKIh365jK @AnneLaureHuber1 @Inserm 🇫🇷

[Will Hill @DrWilliamHill]

We're changing our environment faster than our biology can adapt. Papers like this make clear that understanding the immunological consequences of environmental exposures is central to human health.

[Nature Metabolism @NatMetabolism]

Adipocyte NADH dehydrogenase reverses circadian and diet-induced metabolic syndrome https://t.co/p77B1i2Ufv