Lucas Farina

Escrevo logo existo.

[Lucas Farina @lucasfarinalima]

@vitorborin_ A velha tentativa de reduzir uma intervenção em mágica. Ignora o quão complexo é o sistema biológica. Post genial. Parabéns pela clareza!!

[MathMatize Memes @MathMatize]

My LaTeX document when I try to insert an image

[Folha de S.Paulo @folha]

#OPINIÃO
📝 Camila Rocha | Privatização da Sabesp é tragédia anunciada. Processo que vem sendo conduzido sob a batuta de Tarcísio de Freitas é o pior possível

https://t.co/onvZGSReGB

[nature @Nature]

A molecular-editing tool that’s small enough to be delivered to the brain shuts down the production of proteins that cause prion diseases, a rare but deadly group of neurodegenerative disorders https://t.co/M1SrrP9SVi

[Brain @Brain1878]

Ahmed et al. review putative mechanisms linking neuronal cholesterol to Alzheimer’s disease, and discuss current strategies for developing a brain cholesterol-modulating pharmacotherapy. https://t.co/cDkV8QkqkI

[Masud Husain @MasudHusain]

Why small mindedness is having big consequences @Brain1878
I live under its shadow. I suspect most of you do too. It is the great mountain of small things. The higher it gets, the bigger the shadow it casts: a malignant darkness that pervades our lives.
https://t.co/tgA8uCdrtH

[Lucas Farina @lucasfarinalima]

@a_pleiade Só coisa fina e maravilhosa de se estudar 😁😁😁

[NEJM @NEJM]

Dengue outbreaks can affect 390 million persons yearly. In a trial involving 16,235 persons in Brazil, the live, attenuated, tetravalent Butantan vaccine was efficacious in all age groups at 2 years. Read the full trial results: https://t.co/YY0iRP2Xqb

[AFRICAN & BLACK HISTORY @AfricanArchives]

On this day in 1942, rock guitarist Jimi Hendrix was born.

James Marshall "Jimi" Hendrix ,was a musician, singer, and songwriter. Despite a relatively brief mainstream career spanning four years, he is widely regarded as one of the greatest and most influential electric guitarists in the history of popular music, and one of the most celebrated musicians of the 20th century.

The Rock and Roll Hall of Fame describes him as "arguably the greatest instrumentalist in the history of rock music."

Born in Seattle, Washington, Hendrix began playing guitar at the age of 15. In 1961, he enlisted in the US Army; he was granted an honorable discharge the following year. Soon afterward, he moved to Clarksville, Tennessee, and began playing gigs on the chitlin' circuit, eventually earning a place in the Isley Brothers' backing band and later finding work with Little Richard, with whom he continued to play through mid-1965. He then joined Curtis Knight and the Squires before moving to England in late 1966 after having been discovered by bassist Chas Chandler of the Animals.

Within months, Hendrix had earned three UK top ten hits with the Jimi Hendrix Experience", "Purple Haze", and "The Wind Cries Mary". He achieved fame in the US after his performance at the Monterey Pop Festival in 1967, and in 1968 his third and final studio album, Electric Ladyland, reached number one in the US. The double LP was Hendrix's most commercially successful release and his first and only number one album. He headlined the Woodstock Festival in 1969 and the Isle of Wight Festival in 1970 as the world's highest-paid performer before dying from barbiturate-related asphyxia on September 18, 1970, at the age of 27.

Hendrix was inspired musically by American rock and roll and electric blues. He favored over driven amplifiers with high volume and gain, and was instrumental in developing the previously undesirable technique of guitar amplifier feedback. He helped to popularize the use of a wah-wah pedal in mainstream rock, and was the first artist to use stereophonic phasing effects in music recordings. Holly George-Warren of Rolling Stone commented: "Hendrix pioneered the use of the instrument as an electronic sound source. Players before him had experimented with feedback and distortion, but Hendrix turned those effects and others into a controlled, fluid vocabulary every bit as personal as the blues with which he began."

Hendrix was the recipient of several music awards during his lifetime and posthumously.

In 1967, readers of Melody Maker voted him the Pop Musician of the Year and in 1968, Billboard named him the Artist of the Year and Rolling Stone declared him the Performer of the Year. Disc and Music Echo honored him with the World Top Musician of 1969 and in 1970, Guitar Player named him the Rock Guitarist of the Year.

The Jimi Hendrix Experience was inducted into the Rock and Roll Hall of Fame in 1992 and the UK Music Hall of Fame in 2005.

Rolling Stone ranked their three studio albums, Are You Experienced, Axis: Bold as Love, and Electric Ladyland, among the 100 greatest albums of all time and they ranked Hendrix as the greatest guitarist and the sixth greatest artist of all time.

🖋️you can support (donate) or follow our ko-fi page on https://t.co/MkzBtV9AwG (follow the page too for weekly posts roundup)

[revista piauí @revistapiaui]

Há 60 anos, 300 pessoas foram alfabetizadas em 40 horas na primeira experiência em larga escala do método Paulo Freire. Na edição de dezembro da piauí, André Gravatá resgata essa história.
https://t.co/60k6RefSo6

[Pedro Ronchi @PedroRonchi2]

A Vale soterrou Brumadinho. A Braskem afundou Maceió. A Enel apagou São Paulo. A Americanas deu golpe na praça. Mas empresas públicas que são maus exemplos, né?

[Physics In History @PhysInHistory]

Claude Shannon, renowned as the "father of information theory," significantly impacted electrical engineering and computer science. His pioneering work, encapsulated in his 1948 paper "A Mathematical Theory of Communication," established the foundations of information theory, offering a quantitative framework for information transmission and compression.

His 1937 master's thesis demonstrated that electrical circuits could execute logical operations, laying the groundwork for digital circuit design. Shannon also contributed to cryptography during World War II, developed efficient data encoding methods like Shannon-Fano coding, and formulated principles for problem-solving known as Shannon's Maxims. The Shannon-Hartley Theorem and the concept of Shannon Entropy were central to his work. Shannon's contributions are pivotal in modern technologies like the internet, cellular communications, and digital media, and they continue to influence fields like artificial intelligence and data science.

[Brain @Brain1878]

Why do female patients with Alzheimer's disease have more pronounced tau pathology than males? Wang et al. report that amyloid modulates tau phosphorylation in a sex-specific manner, contributing to faster neurofibrillary tangle accumulation in females. https://t.co/6tG01AdHXY

[Michael Okun @MichaelOkun]

What if you looked in a registry of drugs administered from an entire country for hits that may reveal reduced Parkinson's risk? Well they did this is Norway recently.
Key points:
- 31 therapeutic drug classes that were associated with the risk of later being diagnosed with Parkinson.
- Associations with a reduced risk included drugs acting on the renin-angiotensin system, vaccines, antibiotics, and corticosteroids for systemic use.
- Why the renin angiotensin system?
- Explantations could include something about the pathway itself, the induction of hypotension or an unknown factor(s). I favor the later as some other anti-BP drugs did not have the same effect.
- The authors suggest thinking about the general risk factors for hypertension that may be related to a reduced PD risk, such as smoking.
- There were 600 million individual prescriptions in this analysis. WOW!
My take: This type of large data analysis is very interesting although a closer look at the data suggests the hazard ratios were only mildly decreased below 1: Drugs acting on the renin-angiotensin system (HR 0.92, 95% CI 0.89–0.95), corticosteroids for systemic use (0.88, 95% CI 0.84–0.93), and vaccines (0.89, 95% CI 0.82–0.96). Interesting was also the drug classes treating prodromal Parkinson (constipation, urological issues, and depression) associated with an increased risk of subsequent diagnosis of Parkinson's. Those HRs were above 1; 1.6, 1.48 and 1.94. These data sets are great to help us generate hypotheses for future research. I say Alt for Norge; All for Norway. https://t.co/qFXW8pyNel @PdAvengers @ParkinsonDotOrg

[PesquisaFapesp @PesquisaFapesp]

Queda no número de formados em licenciaturas ameaça a #educação básica brasileira. Pesquisadores defendem a urgência da criação de políticas de valorização da carreira #docente e a adoção de reformulaç��es curriculares. https://t.co/nmEVatkQCL

[Dr. María D. Mayán @MariaDMayan]

👉 I didn’t get the funding for projects on mRNA-research for most of my career. Now that the subject is considered more important, there was even a study done in the Harvard Business Review that tried to find out why I never got money in the past👇🏼🧶 https://t.co/Z0Awqs4yDJ

[Lucas Farina @lucasfarinalima]

@DEletheria Eu só queria ser R1 😭