Nivolumab/Ipilimumab and Pembrolizumab for All Cancers: Australia’s Landmark Tumor-Agnostic Immunotherapy Reimbursement. Co-authored by @VivekSubbiah and @Dr_R_Kurzrock.
Read the full article. https://t.co/zSm95XX5Xl
7 de junio | Día Mundial del Superviviente de Cáncer
Hoy reconocemos la fortaleza, resiliencia y esperanza de quienes han enfrentado el cáncer. Su historia inspira y nos recuerda el valor de cada día y la importancia de acompañar, cuidar y seguir avanzando juntos. 🎗️✨
⚡️ Phase 3 KEYNOTE-B15/EV-304 at #ASCO26: perioperative EV + pembrolizumab vs gemcitabine/cisplatin in cisplatin-eligible MIBC.
EFS HR 0.53. pCR 55.8% vs 32.5%. OS HR 0.65.
First regimen in 25 years to surpass cisplatin-based neoadjuvant chemotherapy in MIBC.
@mattgalsky@ASCO #BladderCancer
https://t.co/7zGdhVKvdD
#ASCO26 abstr 3510
Onvansertib + Chemo + Bev in 1L RAS-mutated mCRC (rPh2 CRDF-004 trial)
💡Onvansertib: PLK1 inhibitor
◾️ORR: 72.2% vs 43.2%
◾️PFS: NR vs 10.97 mo (HR 0.37, p = 0.048)
👉Promising results! A Ph3 is warranted.
@ASCO@OncoAlert
June is National Cancer Survivor Month. Did you know that there are 18 million cancer survivors in the U.S., and that more than 20 percent of those survivors are living with, through, or beyond a breast cancer diagnosis? Learn more: https://t.co/IQnfRKvBWN #CelebrateSurvivorship
Positive lumpectomy margins imply incomplete tumor removal and predict local breast cancer recurrence. This trial assessed margin status +/- pegulicianine fluorescence guided surgery for stages 0–III breast cancers. https://t.co/5cgVyWEAEB
#OncoAlert
In women with previous breast cancer who temporarily discontinued adjuvant endocrine therapy to attempt pregnancy, the frequency of breast cancer events was below the prespecified safety threshold and similar to that in controls (POSITIVE trial). https://t.co/zM3f4SbgjE
RTOG 0815 disponible en JCO.
RT de dosis escalada para el Ca de próstata de riesgo intermedio con ADT a corto plazo.
Seguimiento medio 6,3 años.
ADT redujo la falla de PSA, DM, PCSM, uso de terapia de rescate.
Supervivencia global ❌? Diría peendiente
https://t.co/oArvHgmrIv
💫RENOTORCH: COMBO Toripalimab Axitinib cumple con el objetivo principal en pacientes con RCC💫
@AACR@ASCO@NIH@pfizer@OncoReporte@OncoAlert
💫RENOTORCH: COMBO Toripalimab Axitinib Meets Primary Endpoint in RCC Patients💫 https://t.co/fhgFTRyRxK
Toxicidad de tiempo por tratamiento: Porque no es lo mismo vida que calidad de vida y el tiempo que pasas en el hospital buscándola
https://t.co/cBRCmhalLn
The combination therapy of PD-1 inhibitors plus lenvatinib has promising survival benefits in the management of patients with advanced hepatocellular carcinoma refractory to hepatic arterial infusion chemotherapy.
🔗 https://t.co/RKUX5BYL5I
@OncoAlert
Happy to contribute, finally out: Osimertinib and selpercatinib efficacy, safety, and resistance in a multicenter, prospectively treated cohort of EGFR-mutant and RET fusion-positive lung cancers https://t.co/PoPkMVi39V #LCSM@EGFRResisters
🔥Risk & location of distant metastases in patients with advanced rectal cancer after total neoadjuvant treatment in the RAPIDO trial
https://t.co/LSSBpvqa7t
👉TNT decreases occurrence of (liver-) metastases, but this is counterbalanced by shorter post-recurrence OS
@myESMO@OncoAlert