MET-FIT Lab

Molecular Ecology of Tumor FITness lab led by @shruthy_suresh at @IGIBSocial

Managed by lab members and occasionally SSA

[nature @Nature]

How does gravity affect mitochondrial biology - and what are the implications for space travel?

https://t.co/FPPZ34Ji4Q

[CSIR-IGIB @IGIBSocial]

Registrations are OPEN for the 6th Indian Zebrafish Investigators’ Meeting 2026 (IZIM2026)! If you use zebrafish as a model for your studies, come join the community, meet your peers, build new friendships and listen to some fabulous talks on latest research happening in the field in India and abroad.

Visit https://t.co/2gBTCLYaNt for more details. Last date to register: 15 August, 2026

@SouvikM29933298 @ChetanaX @IGIBSocial @CSIR_IND @CSIR_NIScPR

[MET-FIT Lab @metfitlab]

Paper Cuts #4 | Ironing Out Sex Determination presented by @Dubeylisation
Okashita et al., Nature (2025): https://t.co/XfChieAAx7

[MET-FIT Lab @metfitlab]

✨ Since January, our lab has begun an alternate‑weekly Journal Club series — presenting impactful papers and sharing short write‑ups in our own words.

We’ll be posting every other week — snapshots of our discussions + reflections to follow!

[CSIR-IGIB @IGIBSocial]

In the second episode of the #MeetThePI series, @Debojyoti_C shares his personal journey in science so far and reflects on the people and experiences that have shaped his path. He also talks about his team at @IGIBSocial and offers insights into his research.

@SouvikM29933298 @CSIR_IND @CSIR_HRDG
Watch here:https://t.co/bCIztE65ww

[MET-FIT Lab @metfitlab]

Paper Cuts #3 | JC by Poorva
Featuring Patel et al., Nature (2026): Ageing promotes metastasis via activation of the integrated stress response.

Ageing suppresses primary tumour growth but promotes metastasis.
https://t.co/OWDg7zRAHV

[Waggoner Lab @LabWaggoner]

Cuproptosis-immunity crosstalk informs strategy to overcome immunotherapy resistance @CellCellPress
https://t.co/eia1DAd34T @BoyiGan @MDAndersonNews

[MET-FIT Lab @metfitlab]

First approved CAR-T against solid tumor.
Claudin-18 isoform 2-specific CAR T-cell therapy (satri-cel) versus treatment of physician's choice for previously treated advanced gastric or gastro-oesophageal junction cancer.
https://t.co/BLMpCp3KiK

[Cancer Discovery @CD_AACR]

Now online: Blockade of Tumor-Intrinsic TGFβ Signaling Drives Hyperprogression in Small Cell Lung Cancer https://t.co/5gBeRnZdqv

[Waggoner Lab @LabWaggoner]

CD4+ T cells impair tumor growth through IL-3 and TNF-dependent vascular damage @ScienceMagazine @NIH
https://t.co/bvIxkNLDOs

[MET-FIT Lab @metfitlab]

✨ Continuing our alternate-weekly Paper Cuts series
✨ 2nd Paper Cut of the year - JC by @amishaaab —featuring Cassandras et al., Nature (2026): “Glucocorticoid–FAS axis drives immune evasion in metastatic seeding.”
🔗 https://t.co/V9DPhJUYzn

[MET-FIT Lab @metfitlab]

First JC of the year was presented by @VermaPalavi99 on : "Critical role for a high-plasticity cell state in lung cancer''

and here is the link of the paper : https://t.co/nr2fJLgp85

[Science Immunology @SciImmunology]

A new Science #Immunology study highlights an approach called Effero-seq, which shows that #efferocytosis of tumor cells in mouse models of melanoma can induce protumoral functions in #macrophages. @meravcohen8 https://t.co/AD8rXbbvbZ

[Cancer Cell @Cancer_Cell]

A conserved re-epithelialization program underlies malignancy in pancreatic ductal adenocarcinoma https://t.co/QVCF5YFwqL

[Molecular Cell @MolecularCell]

In vivo single-cell ribosome profiling reveals cell-type-specific translational programs during aging https://t.co/y1UlM1mE1m

[Cell Press @CellPressNews]

"Mitochondria-lysosome coupling contributes to lysosome acidification and aging"

Read more in MOlecular Cell: https://t.co/6xwrPezn3t

Chuankai Zhou & colleagues
@molecularcell

[MET-FIT Lab @metfitlab]

Welcoming our first dissertation student @Akhil_3600 to the lab!
Wishing you a journey filled with curiosity, growth, and discovery — and hoping to see your valuable contributions ahead.

[Nature Reviews Cancer @NatureRevCancer]

#Review 🚨
Cancer cells dynamically rewire immune checkpoint expression across multiple layers. Understanding these mechanisms could unlock new biomarkers and improve immunotherapy outcomes.
📖👇
https://t.co/VQtz7osPFt

[Journal of Experimental Medicine @JExpMed]

Yuki Honda Keith, Tri Giang Phan et al. @garvaninstitute show that tissue-resident CSF1R-dependent CD169⁺ #macrophages localize deep in the skin. They surround growing tumors and directly suppress #melanoma growth independent of T and B cells. https://t.co/lFm7aG6SdX

[MET-FIT Lab @metfitlab]

🎥✨ Our PI shares her journey in Life of a PI — a story of science, leadership, and inspiration. Watch now on YouTube! https://t.co/Lx7b9pVIL8

[Shruthy Suresh (Aggarwal) @shruthy_suresh]

Delighted to share my research journey, dreams & about our lab at @IGIBSocial in the first episode of the #MeetThePI series. Hopeful for awesome science with my awesome team. I plan to take a talented & passionate PhD student in December, please apply to IGIB if interested.