New paper out!
We developed localizable chemigenetic fluorescent sensors for key metal ions (K⁺, Na⁺, Ca²⁺, Mg²⁺, Zn²⁺, etc.). Our K⁺ indicators work beautifully in live cells and neurons. Samples available on request.
Huge thanks to @DeenSun3 and Kai @mpi_mr_hd!
Link 👇
Had the pleasure of hosting my former colleague
@Nieves_P_R who comes to visit me from Saarbrücken! It was a wonderful (@LcsoLab alumni) reunion filled with great conversations, tasty Spanish food, and a very challenging hiking.😉 Looking forward to more such visits!
Our synthesis of the bisnortriterpenoid rubriflordilactone B, which features a [2,3]-Wittig−Still rearrangement, a Friedel−Crafts cyclization and an E1cB reaction/transesterification/oxa-Michael addition cascade, is now out in @J_A_C_S : https://t.co/2sLCKUnTtV
Have a look @ChemRxiv on a new class of peptide-cyanobenzene dye photocatalysts developed by @Xingyuu_Liu in collaboration with Dr. Anne Sophie Chauvin and Wei Cai/ @Beatfierz@LCBM_EPFL
- https://t.co/wljBQhGnvF
Bicyclopropenyls are among the least investigated constitutional isomers of benzene, as difficult to access: This changes now with the work of Xiangdong @Xiangdong__Li combining CpBX reagents wit gold and silver catalysis just published @J_A_C_S
https://t.co/pDJ9ICYKG3
A big thank you to everyone involved: Lennart Nickel,
@hsi_yin, @JulienHiblot and Kai Johnsson.
For more background on the split-HaloTag system, check out our original paper here:
https://t.co/3ZvCEDbrrG
Check out our perspective article discussing the renaissance of gem-carbodications C2+ in Chem @Chem_CP#OpenAccess Congratulations to Yiwei and Jan!
https://t.co/c0ZDCi9dUP
Finally online. Another report on radical homopolymerization of 1 olefin monomers, which are typically regarded as non-homopolymerizable substrates in textbook.
Excited to present the first paper from the Park group, published today in @ScienceMagazine! We found a user-friendly, mild reaction conditions for exchanging an oxygen in heterocycles with nitrogen groups. Congrats Donghyeon, Jaehyun, and the team!
https://t.co/N905d40wxk
We are finally online! 🎉🎉Check out our new website!! https://t.co/gNI375DXV3
Have a look and if you are interested in joining our group, simply reach out!
Come be our colleague 👇. Two positions (synthetic organic and (bio)analytical) open at our institute (LOC). Amazing students and staff, colleagues, facilities, location, and long-term funding perspectives. What are you waiting for? Apply today 😀. @ETH_DCHAB#chemjobs
Our Gentle Rhodamines is finally published @ACSCentSci.
See the healthy cytoskeleton free from photodamage even after 800 frames! 🦾💪
https://t.co/aN7gNl1iaV
Great collaboration with Julian Kompa, the Johnsson group, and Spirochrome! @JulianKompa@spirochrome@TianyanL
WHaloCaMP is a chemigenetic calcium indicator based on HaloTag that can be combined with different rhodamine dyes for multiplexed or FLIM imaging in vivo, as demonstrated in neuronal cultures, brain slices, Drosophila, zebrafish larvae and mouse brain.
https://t.co/bL751a2Mg7
Preprint alert🚨Did you ever experience issues in labeling kinetics and fluorescence brightness, when working with SNAP-tag in live cells?
Our newly developed SNAP-tag2 system might be the solution!
🚀Check out our latest preprint on #bioRxiv: 🔗https://t.co/e5lTpVCuya
(1/4)
🚨Excited to share my latest postdoc work in this #biorxiv preprint on developing split-HaloTag recorders for capturing cellular transient kinase activity, Kinprola (kinase activity dependent protein labeling).
https://t.co/iAUx1XG8gj 🧵 (1/7)
Job Offer: Assistant Professor (tenure track) in Inorganic Chemistry at University of Geneva @UNIGEnews
Starting date: July 1, 2025 or upon mutual agreement
More info: https://t.co/CmOU3TiFbA
#scs#unige#job#inorganic#professor#Switzerland
📢We are hiring!
I am looking for a PhD student to join our young research team which is currently based at @ETH_DCHAB!
#PhDposition in Protein Chemistry and Biocatalysis, funded by @snsf_ch
Interested? Apply here: https://t.co/dURUZVVrhU
RT appreciated!