After our previous studies of convalescent
#COVID donors, a new chapter analyzing the acute phase of disease @ljiresearch@profshanecrotty
Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity https://t.co/VOHGCNf4xo
Calling Eco/evol students: Interested in learning how to code in R? Sign up for our program! We did a shorter session this summer & it was amazing to see how much students can learn with just a few hours a week!
1/n Our Collaborative "Single-Cell Omics Reveals Dyssynchrony of the Innate & Adaptive Immune System in Progressive #COVID19" paper is now on @medrxivpreprint. We provide @10xGenomics#scRNAseq, #Cite, #TCRseq & #BCRseq: my nonimmunologist's tweets follow https://t.co/zMKBoC18vH
Excited to share our preprint on using machine learning to predict preterm birth risk from ~40,000 electronic health records from Vanderbilt and UCSF. Great collaboration lead by @abin_abe with: @msirota84, @RokasLab, @CosminABejan, @Velez_Edwards, others. https://t.co/EunlR9vajK
Interesting way to efficiently parallelize all pairwise comparisons. I still remember the days I had to parallelize on just running IBD analysis among 15,000 individuals...
https://t.co/2NZdA2Eenl
Excited to share our preprint, describing the (surprisingly many) routes an antiviral protein can take to evolve and maintain potency against viruses. Shout out to fantastic trainee coauthors @candiceleilani & @afeez_sodeinde, + @memerman@HarmitMalik.
https://t.co/O0SoxwG8Ve
Our latest paper describes paratyping - a new way to analyse immune repertoires. Read about it here!
https://t.co/922WuJgoBl
#antibody#immunology#bioinformatics
@nataliexdean Importance cannot be overstated: "At the end of April, health authorities also plan to roll out a large-scale antibody study, testing random samples of 100,000 people across Germany every week to gauge where immunity is building up." That's the only way forward.
Our new structural analysis of Ab repertoires supports substantial levels of Ab baseline rep functional commonality, and identifies structural responses to vaccination. If you can share COVID-19 Rep-seq data, we will build convergent response libraries!
https://t.co/n0JTmYMERq
Together, I believe these (and other case-based) strategies can bring down the epidemic. This is the Apollo program of our times. Let's get to it. 19/19
A serological assay to detect SARS-CoV-2 seroconversion in humans | medRxiv| Much needed breakthrough from @florian_krammer lab https://t.co/tnaW09i7L4