Nicolas De Neuter

Scientific Leaders Programme Associate - Data Science & Digital Innovation @GSK. Opinions expressed are my own.

[Paul G Thomas @PGTimmune]

We all agree sequencing TCR repertoires is great, but figuring out what epitopes your TCRs are targeting is so much better. Here we present the reverse epitope discovery pipeline: (https://t.co/Dr73I5huCJ). Led by @pogorely, @elisarosix, @Minervina_Asya in @CellRepMed (1/8)

[GreiffLab 💻🔬💊 @victorgreiff]

Types of AIRR Papers in two chapters – because we had too many good ones 😂. A team effort of the Greiff and @SandveGeir lab members. @airr_community

[Peter de Greef @pcdegreef]

Check out in @FrontAging: we studied how antigen-specific T-cell repertoires change during aging and CMV-infection. Really enjoyed the team effort with great people from @rivm and @CTI_UMCUtrecht @BinfUtrecht

[GreiffLab 💻🔬💊 @victorgreiff]

My @airr_community/@TheAbSociety webinar on immune receptor (BCR, TCR) data analysis is now available on-demand for free (including the slides and written answers to all webinar questions; also those we did not have time to answer during the webinar): https://t.co/fymtso04EA

[Andreas Tiffeau-Mayer @andimscience]

What determines the hierarchy of T cell clone sizes? Check out our new study to see what large scale repertoire sequencing combined with mathematical modeling can tell us about this important question. https://t.co/iGBJ7Itqdq

[Mikhail Pogorelyy @pogorely]

Just 10000 TCRbetas are enough to distinguish you from any other person on Earth, including your potential evil twin (first author: @ThomasDupic)
https://t.co/7uR4Kttgs6

[Paul G Thomas @PGTimmune]

New preprint from a collab. with Phil Bradley @fredhutch! Linking T cell receptor sequence to transcriptional profiles with clonotype neighbor graph analysis (CoNGA). We apply CoNGA to several TCR and GEX datasets (1/5) 1st author @sschattgen https://t.co/gVqvUa6BLe

[TCRex tool @TcrexTool]

Building further on the great work by the groups of @antigenomics and @grigory_efimov , we created a TCR-epitope prediction model for the #SARS-CoV-2 epitope YLQPRTFLL for use in #AIRRseq data and #COVID19 studies. Check it out at https://t.co/ANSGKHtikL! @biominaBE @uantwerpen

[Mikhail Shugay @antigenomics]

1/5 Was a great pleasure to collaborate with Grigory Efimov's @grigory_efimov lab on the analysis of T-cell repertoires in #COVID-19 patients, identifying public T-cell responses to #SARS-CoV-2 antigens in #COVID-19-exposed donors. Main findings of [https://t.co/3mQrP3XfQc] are:

[Mikhail Pogorelyy @pogorely]

Happy to share our preprint (https://t.co/jX61XwRuoo) about longitudinal deep TCRseq after mild #COVID19 (first author: @Minervina_Asya).
Two donors, both were sampled before and on day 15, 30, 37, 45 timepoints post-infection. (1/10)

[Anastasia (Asya) Minervina @Asya_Minervina]

Our collaborative project (@pogorely, @elisarosix, @BensoudaMeriem, @an_franke, @ChudakovM and others) about longitudinal #TCR repertoire sequencing after #SARSCoV2 infection is now also on biorxiv. https://t.co/LtcOmFJPth

[Kris Laukens @KrisLaukens]

A big day for @ndeneuter, defending his PhD on machine learning for immunology decision support. PhD nr 9 in my @biominaBE team @UAntwerpen !

[B-T.CR @bcr_tcr]

Open postdoc position in the Matsen group at Fred Hutch https://t.co/abCBTMa3ov

[Tony Wyss-Coray @wysscoray]

We find granzyme positive CD8 T cells next to degenerating neurons in hippocampi of Alzheimer’s patients. A smoking gun and a dead body but more work will be needed to prove that that gun killed the neuron. More here https://t.co/IsrUEy9bGQ and here https://t.co/VUomVHIop0

[TCRex tool @TcrexTool]

The @TCRexTool paper demonstrating the identification of the epitope specificity of TCR repertoires using our prediction models and enrichment analysis approach has been published in @FrontImmunol! https://t.co/p019Q1gdGM.

[Kris Laukens @KrisLaukens]

We have a new job opening @UAntwerpen @biominaBE for a postdoc in the area of artificial intelligence for small molecule structure elucidation. Please spread the vacancy. #vacancy #AI #mass #spectrometry https://t.co/RiqBkqv0o9

[Aridaman Pandit | अरिदमन पण्डित @PanditAridaman]

Our tool "RTCR surpassed all other tools in both recall and accuracy"
"RTCR is the best choice"
has been benchmarked to be best again!
@BinfUtrecht @UMCURRCI #TCR
Tools for fundamental analysis functions of TCR repertoires: a systematic comparison https://t.co/oLj1OXZA8W

[Nicolas De Neuter @ndeneuter]

Extremely proud of my PI @KrisLaukens for making it to the top 3 promising AHA! award nominees of @AntwerpSrl 's Innovation Night.

[Pieter Meysman @chevaliersf]

Talk by Ayse Bassez from the KUL on single cell RNA and TCR seq of biopsies of breast cancers treated with pembrolizumab. #ATCR19