Pia Lavriha

Researcher in the @KorkhovLab at ETH Zurich and Paul Scherrer Institute. Avid reader and an overly passionate F1 fan.

[Korkhov Lab @KorkhovLab]

Our study on the lipid dependence of Cx32 gap junction channel conformations is now out in @NatureComms. Amazing work by @PLavriha, @FluriCarina, and Jorge Hernández González!
https://t.co/n8u7dRdmr6

[Korkhov Lab @KorkhovLab]

Our investigation of lipid dependence of Cx32 gap junction channel conformations is now online on @biorxivpreprint. Great work by @PLavriha, @FluriCarina and Jorge Hernández González!
https://t.co/qY1wddLPcs

[Korkhov Lab @KorkhovLab]

Our joint study led by @BasurajSK and Oneda Leka, on the interactions between botulinum neurotoxin BoNT/A1 and its receptor SV2B, is now out in @NatureComms. This was a great collaboration with the group of Richard Kammerer (@psich_en)!
https://t.co/VQzCf0BZ0F

[Korkhov Lab @KorkhovLab]

Our study led by @xinyue_ding, joint with Simone Aureli, @gervasiolab, and @Picotti_Lab, describing the structural basis of Cx36 gap junction channel inhibition by small molecule drugs, is out in @CellDiscovery 👇
https://t.co/wAhqmPHQqH

[Pia Lavriha @PLavriha]

@BenHale95 this is iconic! congrats on the paper 🤩🎉

[Snijder Lab @snijderlab]

And here is our first ever #TikTorial (?🤨) of our newest @ScienceMagazine paper! Tweetorial coming soon 🧵

[Pia Lavriha @PLavriha]

guys check this out!

[Korkhov Lab @KorkhovLab]

Our paper on integrative structural biology analysis of adenylyl cyclase AC8 and its interactions with regulators is now out in @emboreports 👇
https://t.co/lVgOo2nxxw

[Ved Mehta @vedmeht89]

A beautiful summary of our recent findings from the @KorkhovLab on the structure and function of membrane bound adenylyl cylases is out. A very cool class of proteins often over shadowed by GPCRs (also cool). Great colleague=great science. Good job team!
https://t.co/N6QyMqQjpc

[Korkhov Lab @KorkhovLab]

Last Thursday we went to test how well our lab skills translate to other activities. ✨ We tested our problem solving skills in boda borg and made cocktails, which is almost like preparing buffers (but a bit tastier 🤫). Here are some impressions from our group activity!

[Basavraj khanppnavar @BasurajSK]

Another wonderful study from our colleagues @PLavriha & @yufei_han who further characterised the interactions of 2-APB and #antimalarial drugs with two other isoforms #connexin Cx32 & Cx43 #channels using cryo-EM and cellular assays.

[Pia Lavriha @PLavriha]

I am very happy our study on Connexin interaction with drugs and their influence on gap junction channel permeability is out on biorxiv. 🥳 many thanks to @yufei_han_ , @KorkhovLab and everyone who helped with the project ✨

[Korkhov Lab @KorkhovLab]

We are excited to share our manuscript on connexin gap junction channel interactions with drugs, led by @PLavriha and @yufei_han_, together with @xinyue_ding, @qichao8886 and @anandvaithia. Now on bioRxiv 👇
https://t.co/hkvpP7ey2a

[Korkhov Lab @KorkhovLab]

Our study, led by Xinyue Ding in collaboration with @gervasiolab, exploring the molecular mechanisms of Cx36 gap junction channel inhibition by antimalarial drugs is now online👇
https://t.co/v25MjVEu56

[Korkhov Lab @KorkhovLab]

Amazing seminar on 7TM receptors today at @psich_en by @arshukla !

[Pia Lavriha @PLavriha]

@vedmeht89 @KorkhovLab thank you Ved ☺️

[Pia Lavriha @PLavriha]

A bit of an update! On Thursday I successfully defended my PhD. 🥳 I am extremely grateful to all who helped me on the way and made my PhD journey in the @KorkhovLab an amazing experience. 🎉🎊

[Pia Lavriha @PLavriha]

@vedmeht89 Congratulations Ved! Amazing work :)

[Ved Mehta @vedmeht89]

https://t.co/manUvPfJgb
My first paper as a postdoc in the lab David Drew is out
Check-out the.first structure of a unique transporter which is regulated by a voltage sensing domain.
Great team work!!

[Mike Hudema @MikeHudema]

"Please make no mistake. Climate change is the biggest threat to global security that modern humans have ever faced." Sir David Attenborough.

No time to wait. #ActOnClimate

#climate #energy #wildfires

[eLife - the journal @eLife]

The #CryoEM structure of the connexin-43 gap junction channel in a putative closed state helps researchers develop a mechanistic model for connexin activation. https://t.co/wGSvS7MgXC

[Ved Mehta @vedmeht89]

Our paper on the structural and functional studies on AC8 is on bioarxiv.
Great effort by the team! It is great to see implementation of complimentary techniques such as LiP-MS that add to Cryo-EM in order to probe structural and functional questions
https://t.co/htxm3v3SSa

[D-BIOL @ ETH Zurich @ETH_DBIOL]

The paper by @KorkhovLab, joint with @Picotti_Lab and Mario Bortolozzi group (@UniPadova), out in @ScienceAdvances, describes the cryo-EM structures of Cx32 channels and reveals a molecular defect in hemichannels of CMT1X-associated Cx32 mutants. More: https://t.co/SCjFoNfs0S