Pingsheng Liu

Lipid droplet biology, focus on evolution of LD using isolation/proteomics, conserved protein study, plus informatics analysis, from bacteria to humans

[Pingsheng Liu @PLIU74726252]

Another student, Bin Pan obtained his PhD, congratulation!

[Biophysics Reports @BiophysRep]

📢 Congratulations to Weibo Cai on their study "Nanobody PET tracer enables GPA33 expression profiling for precision diagnosis of colorectal cancer" published in Biophysics Reports (Online First).
🔗 https://t.co/x5YJH1sfnq
#GPA33 #Colorectalcancer #Nuclearmedicine #Nanobody #Molecularimaging

[Biophysics Reports @BiophysRep]

📢 Congratulations to Yalan Zhu on their review "Molecular mechanisms of CBASS-mediated bacteriophage defense" published in Biophysics Reports (Online First).
🔗 https://t.co/hFROKecuoD
#CBASS #Programmedcelldeath #AntiCBASS #CDNTase #Immuneevasion9

[Biophysics Reports @BiophysRep]

📢 Congratulations to Lei Kang on their study "[64Cu]Cu-NOTA-Ivonescimab: a novel PET tracer for imaging VEGF expression in colorectal carcinoma" published in Biophysics Reports (Online First).
🔗 https://t.co/nJird02GdU
#ImmunoPET #Cu64 #VEGF #Radioactivetracer #Positronemissiontomography #Colorectalcancer

[Biophysics Reports @BiophysRep]

📢 Congratulations to Zufar Gabbasov on their study "Increased impact of GPIb receptors on platelet adhesion under flow in severe COVID-19" published in Biophysics Reports (Online First).
🔗 https://t.co/fUQg8YLtbC
#COVID19 #Thrombosis #Platelet #GPIb

[Protein & Cell @Protein_Cell]

Issue 9 of Protein&Cell here! https://t.co/ChrHD43BHJ

[Biophysics Reports @BiophysRep]

📢 Congratulations to Kai Huang on their review "Cyclic stretch and oxidative stress induced miRNAs in vascular remodeling" published in Biophysics Reports (Online First).
🔗 https://t.co/lK8nJlK4Bl
#smiRNAs #Cyclicstretch #Mechanotransduction #Oxidativestress #ROS

[Biophysics Reports @BiophysRep]

📢Congrats to Haiyan Xu on their study "Construction of genetically encoded biosensors for monitoring cytosolic and mitochondrial H2O2 in response to nanozymes in THP-1 cells" published in Biophysics Reports (Online First).
🔗https://t.co/SJaGfS0a98
#Nanozymes #Oxidoreductase

[Mirian Krystel De Siqueira @DeSiqueiraMK]

Fat Cells in Full Bloom!
Check out our cover on @CellReports @CellPress @ClaudioVillanu @uclaibp
1/5 In a vibrant homage to Van Gogh's iconic Sunflowers, we introduce the Rosiflowers - a wonder born from the fertile depths of the adipose stromal vascular fraction.

[Pingsheng Liu @PLIU74726252]

We isolated and omics analyzed lipid droplets from human carotid artery plaques. Enrichment (16.5%) of arachidonic acid in cholesteryl ester indicates that the plaque is an inflammatory core. https://t.co/7twe7t2Rtk

[Biophysics Reports @BiophysRep]

📢Congrats to Jiangtao Guo on their study "Structural basis for the ion selectivity of potassium-chloride cotransporter KCC4 revealed by cryo-EM titration" published in Biophysics Reports (Online First).
🔗https://t.co/qSSp5co2KE
#KCC4 #CryoEMTitration #MDsimulation

[Biophysics Reports @BiophysRep]

📢Congratulations to Shuguang Tan on their study "Rapid identification of antigen-specific TCRs for cancer immunotherapy" published in Biophysics Reports (Online First).
🔗https://t.co/paqj23XIr8
#Immunopeptide #SingleCellSequencing #TCR

[Biophysics Reports @BiophysRep]

📢Congratulations to Fan Yu on their review "The dual function of mitophagy in ferroptosis" published in Biophysics Reports (Online First).
🔗https://t.co/DXQLmGhZiT
#Mitophagy #Ferroptosis #ROS #Iron

[Biophysics Reports @BiophysRep]

📢Congratulations to Weiqian Cao on their review "Recent advancements in sample pretreatment methods for glycoproteomics" published in Biophysics Reports (Online First).
🔗https://t.co/pXRXU8y5oE
#Glycoproteomics #SamplePretreatment #EnrichmentStrategies #HighThroughputAnalysis

[Biophysics Reports @BiophysRep]

📢Congratulations to Yusong R. Guo on their review "Interactions between membrane proteins and lipid membrane revealed by cryoEM" published in Biophysics Reports (Online First).
🔗https://t.co/le6mSdYptW
#MembraneProtein #ProteinLipidInteraction #CryoEM

[Pingsheng Liu @PLIU74726252]

We identified a novel mitochondrial protein MNP33 from the dark proteome. MNP33 shifts cellular lipid metabolism, favoring cholesteryl ester storage over triacylglycerol via stabilization of ACAT1, and is associated with closer ER-mitochondria contacts. https://t.co/bJNOjVNBfi

[Pingsheng Liu @PLIU74726252]

We isolated skeletal muscle lipid droplets from athletes and T2DM. Comparative proteomics resolves Athlete’s Paradox by three determinative factors for Athlete’s Good LDs and T2DM's Bad LDs: LD-associated ATGL, LD-anchored mitochondria LDAM, cytoskeleton. https://t.co/48A7ejPu5i

[Qiang Guo @QiangGuo_EM]

The work was done together with Prof. Xueliang Zhu and Prof. Miao Gui. Like always, we prepared a Cover proposal, however @NatureComms does not have a cover 😅

[Bei Liu @dr_beiliu]

Live-cell biosensors based on the fluorescence lifetime of environment-sensing dyes: Cell Reports Methods https://t.co/KjgOaYkTTn

[Xiaolei Liu @erin_liuxiaolei]

Big thanks to Prof. Peter Tontonoz and Lauren F. Uchiyama @UCLA for their insightful highlight on a recent Nature paper: DIESL fuels a DGAT-independent triglyceride synthesis pathway. @life_metabolism @JohnSpeakman4 Learn more: https://t.co/99yjRtgUxH